{"EMPIAR-12044":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of inhibitor 172 bound human cystic fibrosis transmembrane conductance regulator E1371Q mutant","directory":"data/Movies","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":10700,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Single particle cryo-EM analysis of inhibitor 172 bound cystic fibrosis transmembrane conductance regulator E1371Q mutant","principal_investigator":[{"author_orcid":"0000-0001-8933-9286","middle_name":null,"organization":"University of Missouri-Columbia","street":null,"town_or_city":"Columbia","state_or_province":"Missouri","post_or_zip":"65211","telephone":null,"fax":null,"first_name":"Xiaolong","last_name":"Gao","email":"xgdz2 [at] umsystem.edu","country":"United States","entry":"EMPIAR-12044"},{"author_orcid":null,"middle_name":null,"organization":"University of Missouri-Columbia","street":null,"town_or_city":"Columbia","state_or_province":"Missouri","post_or_zip":"65211","telephone":null,"fax":null,"first_name":"Tzyh-Chang","last_name":"Hwang","email":"thwang [at] health.missouri.edu","country":"United States","entry":"EMPIAR-12044"}],"status":"REL","deposition_date":"2024-04-17","release_date":"2024-08-26","obsolete_date":null,"update_date":"2024-08-27","corresponding_author":{"author":{"author_orcid":"0000-0001-8933-9286","middle_name":null,"organization":"University of Missouri-Columbia","street":null,"town_or_city":"Columbia","state_or_province":"Missouri","post_or_zip":"65211","first_name":"Xiaolong","last_name":"Gao","country":"United States"}},"authors":[{"author":{"name":"Gao X","author_orcid":"0000-0001-8933-9286"}},{"author":{"name":"Hwang T","author_orcid":null}}],"cross_references":["EMD-43014"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Gao X","author_orcid":"0000-0001-8933-9286"},{"name":"Yeh HI","author_orcid":"0000-0001-5123-6185"},{"name":"Yang Z","author_orcid":null},{"name":"Fan C","author_orcid":"0000-0003-1211-3427"},{"name":"Jiang F","author_orcid":null},{"name":"Howard RJ","author_orcid":"0000-0003-2049-3378"},{"name":"Lindahl E","author_orcid":"0000-0002-2734-2794"},{"name":"Kappes JC","author_orcid":null},{"name":"Hwang TC","author_orcid":"0000-0002-1967-8167"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore","volume":"15","country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1038/s41467-024-50641-1","pubmedid":"39107303","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"6.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8v81"],"entry_doi":"10.6019/EMPIAR-12044"}}