{"EMPIAR-11954":{"imagesets":[{"segmentations":[],"name":"clone 7-scFv2:IgE-Fc2–4(G335C):FcεRIα(W156C) complex","directory":"data","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":592,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.8521,"pixel_height":0.8521,"micrographs_file_pattern":"data","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"AI120510","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"AI115469","country":"United States"},{"funding_body":"National Institutes of Health (NIH)","code":"HL141493","country":"United States"}],"version_history":[],"title":"Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex","principal_investigator":[{"author_orcid":"0000-0002-3664-0072","middle_name":null,"organization":"Department of Structural Biology, Stanford University School of Medicine","street":null,"town_or_city":"Stanford","state_or_province":null,"post_or_zip":"94305","telephone":null,"fax":null,"first_name":"Theodore","last_name":"Jardetzky","email":"tjardetz [at] stanford.edu","country":"United States","entry":"EMPIAR-11954"},{"author_orcid":"0000-0003-0238-7846","middle_name":null,"organization":"Department of Molecular and Cellular Physiology, Stanford University School of Medicine","street":null,"town_or_city":"Stanford","state_or_province":null,"post_or_zip":"94305","telephone":null,"fax":null,"first_name":"Georgios","last_name":"Skiniotis","email":"yiorgo [at] stanford.edu","country":"United States","entry":"EMPIAR-11954"},{"author_orcid":"0000-0001-8746-3339","middle_name":null,"organization":"Department of Rheumatology and Immunology, University Hospital Bern","street":null,"town_or_city":"Bern","state_or_province":null,"post_or_zip":"3012","telephone":null,"fax":null,"first_name":"Alexander","last_name":"Eggel","email":"alexander.eggel [at] unibe.ch","country":"Switzerland","entry":"EMPIAR-11954"}],"status":"REL","deposition_date":"2024-03-08","release_date":"2024-03-20","obsolete_date":null,"update_date":"2024-03-20","corresponding_author":{"author":{"author_orcid":"0000-0002-3664-0072","middle_name":null,"organization":"Department of Structural Biology, Stanford University School of Medicine","street":null,"town_or_city":"Stanford","state_or_province":null,"post_or_zip":"94305","first_name":"Theodore","last_name":"Jardetzky","country":"United States"}},"authors":[{"author":{"name":"Pennington LF","author_orcid":"0000-0002-7947-8714"}},{"author":{"name":"Gasser P","author_orcid":"0000-0003-3708-1660"}},{"author":{"name":"Kleinboelting S","author_orcid":null}},{"author":{"name":"Zhang C","author_orcid":"0000-0003-1210-9161"}},{"author":{"name":"Skiniotis G","author_orcid":"0000-0003-0238-7846"}},{"author":{"name":"Eggel A","author_orcid":"0000-0001-8746-3339"}},{"author":{"name":"Jardetzky TS","author_orcid":"0000-0002-3664-0072"}}],"cross_references":["EMD-25136"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Pennington LF","author_orcid":"0000-0002-7947-8714"},{"name":"Gasser P","author_orcid":"0000-0003-3708-1660"},{"name":"Kleinboelting S","author_orcid":null},{"name":"Zhang C","author_orcid":"0000-0003-1210-9161"},{"name":"Skiniotis G","author_orcid":"0000-0003-0238-7846"},{"name":"Eggel A","author_orcid":"0000-0001-8746-3339"},{"name":"Jardetzky TS","author_orcid":"0000-0002-3664-0072"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex","volume":"12","country":"","first_page":null,"last_page":null,"year":"2021","language":"English","doi":"10.1038/s41467-021-27397-z","pubmedid":"34862384","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"52.0 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7sht"],"entry_doi":"10.6019/EMPIAR-11954"}}