{"EMPIAR-11951":{"imagesets":[{"segmentations":[],"name":"Aligned multi-frame micrographs of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent","directory":"data","category":"micrographs - multiframe","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":16017,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.844,"pixel_height":0.844,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The micrographs are motion corrected images of 50 raw movie frames (accumulating 70.2 electron per squared Angstrom in 2.5 second exposure).","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R35GM141871","country":"United States"}],"version_history":[],"title":"Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent","principal_investigator":[{"author_orcid":"0000-0002-9330-0963","middle_name":"R","organization":"Department of Molecular Pharmacology and Therapeutics, Department of Pathology and Cell Biology, Columbia University","street":"630 West 168th Street","town_or_city":"New York","state_or_province":"New York","post_or_zip":"10032","telephone":null,"fax":null,"first_name":"Qing","last_name":"Fan","email":"qf13 [at] cumc.columbia.edu","country":"United States","entry":"EMPIAR-11951"}],"status":"REL","deposition_date":"2024-03-06","release_date":"2024-05-01","obsolete_date":null,"update_date":"2024-05-10","corresponding_author":{"author":{"author_orcid":"0000-0002-9330-0963","middle_name":"R","organization":"Department of Molecular Pharmacology and Therapeutics, Department of Pathology and Cell Biology, Columbia University","street":"630 West 168th Street","town_or_city":"New York","state_or_province":"New York","post_or_zip":"10032","first_name":"Qing","last_name":"Fan","country":"United States"}},"authors":[{"author":{"name":"Zuo H","author_orcid":null}},{"author":{"name":"Park J","author_orcid":null}},{"author":{"name":"Frangaj A","author_orcid":null}},{"author":{"name":"Ye J","author_orcid":null}},{"author":{"name":"Lu G","author_orcid":null}},{"author":{"name":"Manning JJ","author_orcid":null}},{"author":{"name":"Asher WB","author_orcid":null}},{"author":{"name":"Lu Z","author_orcid":null}},{"author":{"name":"Hu G","author_orcid":null}},{"author":{"name":"Wang L","author_orcid":null}},{"author":{"name":"Mendez J","author_orcid":null}},{"author":{"name":"Eng E","author_orcid":null}},{"author":{"name":"Zhang Z","author_orcid":null}},{"author":{"name":"Lin X","author_orcid":null}},{"author":{"name":"Grasucci R","author_orcid":null}},{"author":{"name":"Hendrickson WA","author_orcid":null}},{"author":{"name":"Clarke OB","author_orcid":null}},{"author":{"name":"Javitch JA","author_orcid":null}},{"author":{"name":"Conigrave AD","author_orcid":null}},{"author":{"name":"Fan QR","author_orcid":"0000-0002-9330-0963"}}],"cross_references":["EMD-43966"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Zuo H","author_orcid":"0000-0002-8812-7385"},{"name":"Park J","author_orcid":null},{"name":"Frangaj A","author_orcid":"0000-0002-4990-513X"},{"name":"Ye J","author_orcid":"0009-0004-2353-2162"},{"name":"Lu G","author_orcid":null},{"name":"Manning JJ","author_orcid":"0000-0002-6945-2254"},{"name":"Asher WB","author_orcid":"0000-0001-7437-218X"},{"name":"Lu Z","author_orcid":"0000-0002-4262-1193"},{"name":"Hu GB","author_orcid":null},{"name":"Wang L","author_orcid":null},{"name":"Mendez J","author_orcid":"0000-0002-3317-5654"},{"name":"Eng E","author_orcid":"0000-0002-8014-7269"},{"name":"Zhang Z","author_orcid":null},{"name":"Lin X","author_orcid":null},{"name":"Grassucci R","author_orcid":null},{"name":"Hendrickson WA","author_orcid":"0000-0003-1412-5747"},{"name":"Clarke OB","author_orcid":null},{"name":"Javitch JA","author_orcid":"0000-0001-7395-2967"},{"name":"Conigrave AD","author_orcid":"0000-0002-7232-3891"},{"name":"Fan QR","author_orcid":"0000-0002-9330-0963"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Promiscuous G-protein activation by the calcium-sensing receptor","volume":null,"country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1038/s41586-024-07331-1","pubmedid":"38632411","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":null,"preprint":false}],"dataset_size":"1.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9axf"],"entry_doi":"10.6019/EMPIAR-11951"}}