{"EMPIAR-11875":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif","directory":"data/raw","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":1.058,"pixel_height":1.058,"micrographs_file_pattern":"data/raw/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"FEI Titan Krios microscope operated at 300 kV and equipped with a Gatan K2 Summit detector and a Gatan Quantum GIF LS energy filter. Micrographs were collected in super-resolution mode and fourier-cropped on-the-fly with FOCUS software, consisted of 50 frames for a total exposure time of 10 s and a total dose of 80 e-/Å2. The defocus ranged between –2.2 and –1 μm. Data collected with Serial EM.","image_width":"7676","image_height":"7420"},{"segmentations":[],"name":"Gain reference","directory":"data/gainref","category":"micrographs - single frame","header_format":"DM4","data_format":"DM4","num_images_or_tilt_series":1,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.058,"pixel_height":1.058,"micrographs_file_pattern":"data/gainref/SuperRef_MC6-6_24_Oct18_18.35.07.dm4","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Gain reference","image_width":"7676","image_height":"7420"}],"workflow_file":null,"grant_references":[{"funding_body":"European Research Council (ERC)","code":"ERC-StG-337284","country":"Switzerland"},{"funding_body":"European Molecular Biology Organization (EMBO)","code":"EMBO ALTF-343-2013","country":"Switzerland"},{"funding_body":"European Union (EU)","code":"PROSPECTS, HEALTH-F4-2008-201648","country":"Switzerland"},{"funding_body":"European Research Council (ERC)","code":"ERC-StG-233226","country":"Switzerland"},{"funding_body":"European Research Council (ERC)","code":"ERC-StG-670821","country":"Switzerland"}],"version_history":[],"title":"Human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif","principal_investigator":[{"author_orcid":"0000-0002-7601-210X","middle_name":null,"organization":"Department of Biochemistry, University of Zurich","street":"Winterthurerstrasse 190","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8057","telephone":"41446355572","fax":null,"first_name":"Martin","last_name":"Jinek","email":"jinek [at] bioc.uzh.ch","country":"Switzerland","entry":"EMPIAR-11875"},{"author_orcid":"0000-0002-9576-3267","middle_name":null,"organization":"Department of Biology, Institute of Molecular Systems Biology, ETH Zurich","street":null,"town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8093","telephone":null,"fax":null,"first_name":"Ruedi","last_name":"Aebersold","email":"aebersold [at] imsb.biol.ethz.ch","country":"Switzerland","entry":"EMPIAR-11875"}],"status":"REL","deposition_date":"2024-01-24","release_date":"2024-02-06","obsolete_date":null,"update_date":"2024-02-06","corresponding_author":{"author":{"author_orcid":"0000-0002-7601-210X","middle_name":null,"organization":"Department of Biochemistry, University of Zurich","street":"Winterthurerstrasse 190","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8057","first_name":"Martin","last_name":"Jinek","country":"Switzerland"}},"authors":[{"author":{"name":"Muckenfuss LM","author_orcid":"0000-0003-3558-7211"}},{"author":{"name":"Jinek M","author_orcid":"0000-0002-7601-210X"}}],"cross_references":["EMD-4225"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Clerici M","author_orcid":"0000-0003-2906-0982"},{"name":"Faini M","author_orcid":"0000-0001-8131-7648"},{"name":"Muckenfuss LM","author_orcid":"0000-0003-3558-7211"},{"name":"Aebersold R","author_orcid":"0000-0002-9576-3267"},{"name":"Jinek M","author_orcid":"0000-0002-7601-210X"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex","volume":"25","country":"","first_page":"135","last_page":"138","year":"2018","language":"English","doi":"10.1038/s41594-017-0020-6","pubmedid":"29358758","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature structural & molecular biology","journal_abbreviation":"Nat Struct Mol Biol","issue":"2","preprint":false}],"dataset_size":"1.2 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["6fbs","6fuw"],"entry_doi":"10.6019/EMPIAR-11875"}}