{"EMPIAR-11840":{"imagesets":[{"segmentations":[],"name":"Unaligned multiframe movies in the EER format of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes","directory":"data/24092021_RawData","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":16009,"frames_per_image":1204,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":0.86,"pixel_height":0.86,"micrographs_file_pattern":"data/24092021_RawData/Images-Disc1/GridSquare_*/Data/*.eer","picked_particles_file_pattern":"","picked_particles_directory":"","details":"A dose per physical pixel/s of 5.38 was used, resulting in a total electron dose of 36.4 e-/Å2, fractionated across 172 EPU frames. These were then grouped into 26 frames, resulting in an electron dose of 0.8 e-/Å2 per frame.","image_width":null,"image_height":null},{"segmentations":[],"name":"Aligned micrographs of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes","directory":"data/Raw_data","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":16009,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.86,"pixel_height":0.86,"micrographs_file_pattern":"data/Raw_data/*.mrc","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Raw movie frames are aligned with RELION's own implementation of the MotionCor2 algorithm using an EER fractionation of 45.","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[{"funding_body":"Medical Research Council (MRC, United Kingdom)","code":"MR/T029471/1","country":"United Kingdom"},{"funding_body":"Wellcome Trust","code":"222531/Z/21/Z","country":"United Kingdom"},{"funding_body":"Wellcome Trust","code":"108466/Z/15/Z","country":"United Kingdom"},{"funding_body":"Wellcome Trust","code":"221524/Z/20/Z","country":"United Kingdom"}],"version_history":[],"title":"Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes","principal_investigator":[{"author_orcid":"0000-0001-9551-5514","middle_name":"D","organization":"Wellcome Centre for Cell Biology, University of Edinburgh","street":null,"town_or_city":"Edinburgh","state_or_province":null,"post_or_zip":"EH9 3JR","telephone":"+44 1316507005","fax":null,"first_name":"Marcus","last_name":"Wilson","email":"marcus.wilson [at] ed.ac.uk","country":"United Kingdom","entry":"EMPIAR-11840"},{"author_orcid":"0000-0003-0239-5926","middle_name":null,"organization":"Astbury Centre for Structural Molecular Biology, University of Leeds","street":null,"town_or_city":"Leeds","state_or_province":null,"post_or_zip":"LS2 9JT","telephone":"+44 113 3433079","fax":null,"first_name":"Elton","last_name":"Zeqiraj","email":"e.zeqiraj [at] leeds.ac.uk","country":"United Kingdom","entry":"EMPIAR-11840"}],"status":"REL","deposition_date":"2023-08-25","release_date":"2024-02-01","obsolete_date":null,"update_date":"2024-02-01","corresponding_author":{"author":{"author_orcid":"0000-0001-9132-4737","middle_name":null,"organization":"Astbury Centre for Structural Molecular Biology, University of Leeds","street":null,"town_or_city":"Leeds","state_or_province":"West Yorkshire","post_or_zip":"LS2 9JT","first_name":"Martina","last_name":"Foglizzo","country":"United Kingdom"}},"authors":[{"author":{"name":"Foglizzo M","author_orcid":"0000-0001-9132-4737"}},{"author":{"name":"Burdett H","author_orcid":"0000-0003-4803-9660"}},{"author":{"name":"Wilson MD","author_orcid":"0000-0001-9551-5514"}},{"author":{"name":"Zeqiraj E","author_orcid":"0000-0003-0239-5926"}}],"cross_references":["EMD-17928","EMD-16859"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Burdett H","author_orcid":"0000-0003-4803-9660"},{"name":"Foglizzo M","author_orcid":"0000-0001-9132-4737"},{"name":"Musgrove LJ","author_orcid":null},{"name":"Kumar D","author_orcid":null},{"name":"Clifford G","author_orcid":null},{"name":"Campbell LJ","author_orcid":null},{"name":"Heath GR","author_orcid":"0000-0001-6431-2191"},{"name":"Zeqiraj E","author_orcid":"0000-0003-0239-5926"},{"name":"Wilson MD","author_orcid":"0000-0001-9551-5514"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes","volume":"51","country":"United Kingdom","first_page":"11080","last_page":"11103","year":"2023","language":"English","doi":"10.1093/nar/gkad793","pubmedid":"37823591","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nucleic acids research","journal_abbreviation":"Nucleic Acids Res","issue":"20","preprint":false}],"dataset_size":"10.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8off"],"entry_doi":"10.6019/EMPIAR-11840"}}