{"EMPIAR-11818":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame movies of tilt-series of cryo-FIB milled Mouse Embryonic Fibroblasts with OPA1 overexpression","directory":"data/EMPIAR","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":258,"frames_per_image":4,"frame_range_min":1,"frame_range_max":4,"voxel_type":"UNSIGNED BYTE","pixel_width":1.28,"pixel_height":1.28,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned multi-frame micrographs (EMD-430*/frames/*.tiff) corresponding to 5 tilt series with corresponding gain reference (gain/*dm4) and metadata (mdoc/*.mdoc). Data acquired on a K3 BioQuantum detector with no Volta phase plate. \n\nAcquisition parameters differ for each dataset (named after the corresponding EMDB accession code) and are specified below. \n\nEMD-43067:\n67 tilts in the series.\n\nEMD-43068:\n63 tilts in the series\n\nEMD-43069:\n64 tilts in the series\n\nEMD-43070:\n64 tilts in the series","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)","code":"R35GM142553","country":"United States"},{"funding_body":"National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)","code":"R01DK125263","country":"United States"},{"funding_body":"National Institutes of Health/National Cancer Institute (NIH/NCI)","code":"R37CA248565","country":"United States"},{"funding_body":"Jane Coffin Childs (JCC) Fund","code":"243493","country":"United States"},{"funding_body":"Swiss National Science Foundation","code":"P2BSP3_188112","country":"Switzerland"}],"version_history":[],"title":"Cryo-electron tomogram of mitochondria in cryo-FIB milled mouse embryonic fibroblasts with OPA1 overexpression","principal_investigator":[{"author_orcid":"0000-0002-4849-4148","middle_name":null,"organization":"Department of Molecular Biology, Massachusetts General Hospital","street":"185 Cambridge Street","town_or_city":"Boston","state_or_province":"Massachusetts","post_or_zip":"02114","telephone":null,"fax":null,"first_name":"Luke","last_name":"Chao","email":"chao [at] molbio.mgh.harvard.edu","country":"United States","entry":"EMPIAR-11818"}],"status":"REL","deposition_date":"2023-12-07","release_date":"2024-06-04","obsolete_date":null,"update_date":"2024-06-04","corresponding_author":{"author":{"author_orcid":"0000-0002-4849-4148","middle_name":null,"organization":"Department of Molecular Biology, Massachusetts General Hospital","street":"185 Cambridge Street","town_or_city":"Boston","state_or_province":"Massachusetts","post_or_zip":"02114","first_name":"Luke","last_name":"Chao","country":"United States"}},"authors":[{"author":{"name":"Fry MY","author_orcid":"0000-0002-3209-5492"}},{"author":{"name":"Navarro PP","author_orcid":"0000-0002-9123-1132"}},{"author":{"name":"Ananda VY","author_orcid":"0000-0001-5590-1170"}},{"author":{"name":"Ge Y","author_orcid":"0000-0001-9135-9569"}},{"author":{"name":"McDonald JL","author_orcid":"0000-0002-3715-9619"}},{"author":{"name":"Hakim P","author_orcid":"0000-0002-9018-8179"}},{"author":{"name":"Luce BE","author_orcid":"0000-0002-0107-5181"}},{"author":{"name":"Lugo CM","author_orcid":"0000-0003-4655-8096"}},{"author":{"name":"Chao LH","author_orcid":"0000-0002-4849-4148"}}],"cross_references":["EMD-43067","EMD-43069","EMD-43068","EMD-43070"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Fry MY","author_orcid":"0000-0002-3209-5492"},{"name":"Navarro PP","author_orcid":"0000-0002-9123-1132"},{"name":"Hakim P","author_orcid":"0000-0002-9018-8179"},{"name":"Ananda VY","author_orcid":"0000-0001-5590-1170"},{"name":"Qin X","author_orcid":"0000-0003-3263-0843"},{"name":"Landoni JC","author_orcid":"0000-0002-0318-6707"},{"name":"Rath S","author_orcid":"0000-0001-8839-1285"},{"name":"Inde Z","author_orcid":"0000-0001-5564-1698"},{"name":"Lugo CM","author_orcid":"0000-0003-4655-8096"},{"name":"Luce BE","author_orcid":"0000-0002-0107-5181"},{"name":"Ge Y","author_orcid":"0000-0001-9135-9569"},{"name":"McDonald JL","author_orcid":"0000-0002-3715-9619"},{"name":"Ali I","author_orcid":"0000-0003-2019-5645"},{"name":"Ha LL","author_orcid":"0000-0003-4478-660X"},{"name":"Kleinstiver BP","author_orcid":"0000-0002-5469-0655"},{"name":"Chan DC","author_orcid":"0000-0002-0191-2154"},{"name":"Sarosiek KA","author_orcid":"0000-0002-4618-5085"},{"name":"Chao LH","author_orcid":"0000-0002-4849-4148"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"In situ architecture of Opa1-dependent mitochondrial cristae remodeling","volume":"43","country":"","first_page":"391","last_page":"413","year":"2024","language":"English","doi":"10.1038/s44318-024-00027-2","pubmedid":"38225406","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"The EMBO journal","journal_abbreviation":"EMBO J","issue":"3","preprint":false}],"dataset_size":"8.8 GB","experiment_type":"EMDB","scale":"cell","entry_doi":"10.6019/EMPIAR-11818"}}