{"EMPIAR-11802":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of FOR010 amyloid fibrils","directory":"data/eer","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":4008,"frames_per_image":963,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.934,"pixel_height":0.934,"micrographs_file_pattern":"data/eer/*.eer","picked_particles_file_pattern":"data/Manual_Pick/*.star","picked_particles_directory":"data/Manual_Pick","details":"IC-Krios1 G4 300kV C-FEG\nSelectrisX 10eV slit width, Falcon4i\nCs=2.7mm, C2aperture=50um, ObjAperture=100um\nEFTEM 130kx, nanoprobe spot 5, beam=630nm\nCounting mode, 1pix=0.934 A\n~3 s exposure, EER files save (963 fractions, not gain corrected)\n~40 e/A^2 total dose\n\nThe gain reference (/data/micrographs/20220808_133943_EER_GainReference.gain) is not applied to the micrographs. The NOTES.txt file contains EM information. Thumbnails and power spectra (data/thumbnails) as well as coordinates (/data/Manual_Pick) are provided.","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"German Research Foundation (DFG)","code":"FA 456/23","country":"Germany"}],"version_history":[],"title":"AL amyloid fibril from the FOR010 light chain","principal_investigator":[{"author_orcid":"0000-0003-2123-6816","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Marcus","last_name":"Fändrich","email":"marcus.faendrich [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-11802"}],"status":"REL","deposition_date":"2023-11-27","release_date":"2025-02-21","obsolete_date":null,"update_date":"2025-02-21","corresponding_author":{"author":{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","first_name":"Matthias","last_name":"Schmidt","country":"Germany"}},"authors":[{"author":{"name":"Pfeiffer PB","author_orcid":"0009-0004-3946-3579"}},{"author":{"name":"Banerjee S","author_orcid":null}},{"author":{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}},{"author":{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}}],"cross_references":["EMD-18881"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Karimi-Farsijani S","author_orcid":"0000-0003-2513-1499"},{"name":"Pfeiffer PB","author_orcid":"0009-0004-3946-3579"},{"name":"Banerjee S","author_orcid":null},{"name":"Baur J","author_orcid":null},{"name":"Kuhn L","author_orcid":null},{"name":"Kupfer N","author_orcid":null},{"name":"Hegenbart U","author_orcid":null},{"name":"Schönland SO","author_orcid":null},{"name":"Wiese S","author_orcid":null},{"name":"Haupt C","author_orcid":null},{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"},{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"1.8 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8r47"],"entry_doi":"10.6019/EMPIAR-11802"}}