{"EMPIAR-11801":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of FOR103 amyloid fibrils","directory":"data/micrographs","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2788,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":1.04,"pixel_height":1.04,"micrographs_file_pattern":"data/micrographs/*.tif","picked_particles_file_pattern":"data/Manual_Pick/*.star","picked_particles_directory":"data/Manual_Pick","details":"Krios1 Quantum-K2\nCs 2.7\n300kV EFTEM nanpprobe\nx130k spot 8 beam size 650nm\nc2=50  objective_aperture=100\n\nGIF-K2 counting\n10s exposure 40 frames\ntotal dose at the sample 53.70e/A2\n1 pixel = 1.04A\ndose rate ~3-4 e/pix/s\n\ndefocus range -1.2 to -2.5\n\nThe gain reference (/data/micrographs/CountRef_map_0076_001.dm4) is not applied to the micrographs. The NOTES.txt file contains EM information. Thumbnails and power spectra (data/thumbs) as well as coordinates (/data/Manual_Pick) are provided.","image_width":"3838","image_height":"3710"}],"workflow_file":null,"grant_references":[{"funding_body":"German Research Foundation (DFG)","code":"FA 456/23","country":"Germany"}],"version_history":[],"title":"AL amyloid fibril from the FOR103 light chain","principal_investigator":[{"author_orcid":"0000-0003-2123-6816","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Marcus","last_name":"Fändrich","email":"marcus.faendrich [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-11801"}],"status":"REL","deposition_date":"2023-11-27","release_date":"2024-09-03","obsolete_date":null,"update_date":"2024-09-03","corresponding_author":{"author":{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","first_name":"Matthias","last_name":"Schmidt","country":"Germany"}},"authors":[{"author":{"name":"Pfeiffer PB","author_orcid":"0009-0004-3946-3579"}},{"author":{"name":"Karimi-Farsijani S","author_orcid":"0000-0003-2513-1499"}},{"author":{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}},{"author":{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}}],"cross_references":["EMD-19818"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Karimi-Farsijani S","author_orcid":"0000-0003-2513-1499"},{"name":"Pfeiffer PB","author_orcid":"0009-0004-3946-3579"},{"name":"Banerjee S","author_orcid":null},{"name":"Baur J","author_orcid":null},{"name":"Kuhn L","author_orcid":null},{"name":"Kupfer N","author_orcid":null},{"name":"Hegenbart U","author_orcid":null},{"name":"Schönland SO","author_orcid":null},{"name":"Wiese S","author_orcid":null},{"name":"Haupt C","author_orcid":null},{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"},{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"504.3 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["9eme"],"entry_doi":"10.6019/EMPIAR-11801"}}