{"EMPIAR-11762":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of human TFIIIC bound to tRNA gene","directory":"data/Dataset_1","category":"micrographs - multiframe","header_format":"MRC","data_format":"TIFF","num_images_or_tilt_series":11025,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"data/Dataset_1/211108_hTFIIIC_DNA_*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned multi-frame (40 frames) micrographs were collected in counting mode with a total electron dose of 42.8 electrons/Å2 at defocus range from 0.7 to 1.7 . Gain reference is in CountRef_211108_hTFIIIC_DNA_00001.mrc file.","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Final particles of TauA subcomplex","directory":"data/Dataset_1/TauA_final_particles","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":55079,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"","picked_particles_file_pattern":"data/Dataset_1/TauA_final_particles/211108_hTFIIIC_DNA_*.mrcs","picked_particles_directory":"data/Dataset_1/TauA_final_particles","details":"The directory \"data/Dataset_1/TauA_final_particles\" contains the \".mrcs\" files of the final 3D reconstruction of TauA. These particles were also used for the \"Cryo-EM mapping of particle pair distances at a single-molecule level\" with TauB-dimer particles. The file \"particles.star\" contains the coordinates.","image_width":"352","image_height":"352"},{"segmentations":[],"name":"Final particles of TauB-dimer subcomplex","directory":"data/Dataset_1/TauB_dimer_final_particles","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":35379,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"","picked_particles_file_pattern":"data/Dataset_1/TauB_dimer_final_particles/211108_hTFIIIC_DNA_*.mrcs","picked_particles_directory":"data/Dataset_1/TauB_dimer_final_particles","details":"The directory \"data/Dataset_1/TauB_dimer_final_particles\" contains the \".mrcs\" files of the final 3D reconstruction of TauB-dimer. The file \"particles.star\" contains the coordinates.","image_width":"480","image_height":"480"},{"segmentations":[],"name":"Intermediate particles of TauB-dimer subcomplex for mapping pair distance","directory":"data/Dataset_1/TauB_dimer_pair_distances","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":99217,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"","picked_particles_file_pattern":"data/Dataset_1/TauB_dimer_pair_distances/211108_hTFIIIC_DNA_*.mrcs","picked_particles_directory":"data/Dataset_1/TauB_dimer_pair_distances","details":"The directory \"data/Dataset_1/TauB_dimer_pair_distances\" contains the \".mrcs\" files of Non-Uniform refinement reconstruction of TauB-dimer. These particles were used for the \"Cryo-EM mapping of particle pair distances at a single-molecule level\" with TauA particles. The file \"particles.star\" contains the coordinates.","image_width":"480","image_height":"480"},{"segmentations":[],"name":"Unaligned multi-frame micrographs of human TFIIIC (No DNA sample)","directory":"data/Dataset_2","category":"micrographs - multiframe","header_format":"MRC","data_format":"TIFF","num_images_or_tilt_series":11088,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"data/Dataset_2/hTFIIIC_OG_*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned multi-frame (40 frames) micrographs were collected in counting mode with a total electron dose of 39.6 electrons/Å2 at defocus range from 0.7 to 1.7 . Gain reference is in CountRef_hTFIIIC_OG_113-1_00001.mrc file.","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Final particles of TauA subcomplex (No DNA sample)","directory":"data/Dataset_2/TauA_noDNA_final_particles","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":94103,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"","picked_particles_file_pattern":"data/Dataset_2/TauA_noDNA_final_particles/hTFIIIC_OG_*.mrcs","picked_particles_directory":"data/Dataset_2/TauA_noDNA_final_particles","details":"The directory \"data/Dataset_2/TauA_noDNA_final_particles\" contains the \".mrcs\" files of the final 3D reconstruction of TauA. The file \"particles.star\" contains the coordinates.","image_width":"300","image_height":"300"},{"segmentations":[],"name":"Final particles of TauB-dimer subcomplex (No DNA sample)","directory":"data/Dataset_2/TauB_dimer_noDNA_final_particles","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":125600,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.822,"pixel_height":0.822,"micrographs_file_pattern":"","picked_particles_file_pattern":"data/Dataset_2/TauB_dimer_noDNA_final_particles/hTFIIIC_OG_*.mrcs","picked_particles_directory":"data/Dataset_2/TauB_dimer_noDNA_final_particles","details":"The directory \"data/Dataset_2/TauB_dimer_noDNA_final_particles\" contains the \".mrcs\" files of the final 3D reconstruction of TauA. The file \"particles.star\" contains the coordinates.","image_width":"480","image_height":"480"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of human TFIIIC bound and unbound to tRNA gene","principal_investigator":[{"author_orcid":"0000-0003-2176-8337","middle_name":"W","organization":"European Molecular Biology Laboratory","street":"Meyerhofstraße 1","town_or_city":"Heidelberg","state_or_province":"Baden-Württemberg","post_or_zip":"69117","telephone":null,"fax":null,"first_name":"Christoph","last_name":"Müller","email":"christoph.mueller [at] embl.de","country":"Germany","entry":"EMPIAR-11762"}],"status":"REL","deposition_date":"2023-11-02","release_date":"2024-02-28","obsolete_date":null,"update_date":"2024-02-28","corresponding_author":{"author":{"author_orcid":"0000-0003-2176-8337","middle_name":"W","organization":"European Molecular Biology Laboratory","street":"Meyerhofstraße 1","town_or_city":"Heidelberg","state_or_province":"Baden-Württemberg","post_or_zip":"69117","first_name":"Christoph","last_name":"Müller","country":"Germany"}},"authors":[{"author":{"name":"Seifert-Davila W","author_orcid":"0000-0002-5366-624X"}},{"author":{"name":"Girbig M","author_orcid":"0000-0003-3442-5448"}},{"author":{"name":"Hauptmann L","author_orcid":"0000-0003-3561-4523"}},{"author":{"name":"Hoffmann T","author_orcid":"0000-0002-2980-8324"}},{"author":{"name":"Eustermann S","author_orcid":"0000-0002-4439-7770"}},{"author":{"name":"Müller CW","author_orcid":"0000-0003-2176-8337"}}],"cross_references":["EMD-16715","EMD-16714","EMD-16713","EMD-17447","EMD-17446","EMD-16716","EMD-16717"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Seifert-Davila W","author_orcid":"0000-0002-5366-624X"},{"name":"Girbig M","author_orcid":"0000-0003-3442-5448"},{"name":"Hauptmann L","author_orcid":"0000-0003-3561-4523"},{"name":"Hoffmann T","author_orcid":"0000-0002-2980-8324"},{"name":"Eustermann S","author_orcid":"0000-0002-4439-7770"},{"name":"Müller CW","author_orcid":"0000-0003-2176-8337"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural insights into human TFIIIC promoter recognition","volume":"9","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1126/sciadv.adh2019","pubmedid":"37418517","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science advances","journal_abbreviation":"Sci Adv","issue":"27","preprint":false}],"dataset_size":"3.8 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8clk","8clj","8cli","8cll"],"entry_doi":"10.6019/EMPIAR-11762"}}