{"EMPIAR-11745":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of TDP-43 amyloid fibrils","directory":"data/EM_data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1641,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":1.04,"pixel_height":1.04,"micrographs_file_pattern":"data/EM_data/*.tif","picked_particles_file_pattern":"data/Coordinatesfiles_Morphology*/*_manualpick.star","picked_particles_directory":"data/Coordinatesfiles_Morphology*","details":"The gain reference (/data/EM_data/CountRef_0001.dm4) is not applied to the raw micrographs. The NOTES.txt file contains EM information (copied below). The coordinates are divided into Morphology-1 (/data/Coordinatesfiles_Morphology1) and Morphology-2 (/data/Coordinatesfiles_Morphology2).\n\n---------------------------------------------------------------------------------------------------------------------------------------------------------------------------\nNOTES.txt \n\nEMBL Heidelberg\nKrios1 Quantum-K2\nCs 2.7\n300kV EFTEM nanpprobe\nx130k spot 8 beam size 650nm\nc2=50  objective_aperture=100\n\nGIF-K2 counting\n10s exposure 40 frames\ntotal dose at the sample 52.08e/A2\n1 pixel = 1.04A\ndose rate ~3-4 e/pix/s\n\ndefocus range -1.2 to -2.5","image_width":"3838","image_height":"3710"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"In vitro TDP-43 amyloid fibrils","principal_investigator":[{"author_orcid":"0000-0003-2123-6816","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"Helmholtzstrasse 8/1","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Marcus","last_name":"Fändrich","email":"marcus.faendrich [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-11745"}],"status":"REL","deposition_date":"2023-08-03","release_date":"2024-06-04","obsolete_date":null,"update_date":"2024-06-04","corresponding_author":{"author":{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"Helmholtzstrasse 8/1","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","first_name":"Matthias","last_name":"Schmidt","country":"Germany"}},"authors":[{"author":{"name":"Sharma K","author_orcid":"0000-0003-3375-7168"}},{"author":{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}},{"author":{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}}],"cross_references":["EMD-18715","EMD-18717","EMD-18716"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Sharma K","author_orcid":"0000-0003-3375-7168"},{"name":"Stockert F","author_orcid":"0009-0009-2685-4390"},{"name":"Shenoy J","author_orcid":"0000-0002-0360-645X"},{"name":"Berbon M","author_orcid":null},{"name":"Abdul-Shukkoor MB","author_orcid":null},{"name":"Habenstein B","author_orcid":"0000-0003-3723-9552"},{"name":"Loquet A","author_orcid":"0000-0001-7176-7813"},{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"},{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils","volume":"15","country":"","first_page":null,"last_page":null,"year":"2024","language":"English","doi":"10.1038/s41467-023-44489-0","pubmedid":"38212334","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"280.1 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8qx9","8qxb","8qxa"],"entry_doi":"10.6019/EMPIAR-11745"}}