{"EMPIAR-11708":{"imagesets":[{"segmentations":[],"name":"Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex","directory":"data/H4R-Gq_histamine","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6300,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":0.88,"pixel_height":0.88,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Please use 'CountCDSRef_20220210_IwataLab_96_0000_Feb10_14.54.40.mrc' as a gain reference without rotation or flipping in RELION (Y flipping is necessary for CryoSPARC).\n- Movies were recorded on a Titan Krios with a Cs-corrector.\n- The residual Cs value reported by the Cs corrector is 0.06216 mm.\n- Four digits (0000 to 0017) in the file names represent image shift directions but grouping was not applied during processing.\n- Flux at sample: ~ 1 e/A2/frame","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex","directory":"data/H4R-Gq_imetit","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6462,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"UNSIGNED BYTE","pixel_width":0.88,"pixel_height":0.88,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"- Please use 'CountCDSRef_20211202_IwataLab_99_0000_Dec02_14.17.09.mrc' as a gain reference without rotation or flipping in RELION (Y flipping is necessary for CryoSPARC).\n- Movies were recorded on a Titan Krios with a Cs-corrector.\n- The residual Cs value reported by the Cs corrector is 0.04223 mm.\n- Four digits (0000 to 0017) in the file names represent image shift directions but grouping was not applied during processing.\n- Flux at sample: ~ 1 e/A2/frame","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of the histamine-bound histamine H4 receptor and Gq complex","principal_investigator":[{"author_orcid":null,"middle_name":null,"organization":"Department of Cell Biology Graduate School of Medicine, Kyoto University","street":null,"town_or_city":"Kyoto","state_or_province":null,"post_or_zip":"6068501","telephone":null,"fax":null,"first_name":"So","last_name":"Iwata","email":"iwata.so.2z [at] kyoto-u.ac.jp","country":"Japan","entry":"EMPIAR-11708"}],"status":"REL","deposition_date":"2023-09-29","release_date":"2024-08-23","obsolete_date":null,"update_date":"2025-08-22","corresponding_author":{"author":{"author_orcid":"0000-0002-6939-7718","middle_name":null,"organization":"Department of Cell Biology Graduate School of Medicine, Kyoto University","street":null,"town_or_city":"Kyoto","state_or_province":null,"post_or_zip":"6068501","first_name":"Dohyun","last_name":"Im","country":"Japan"}},"authors":[{"author":{"name":"Im D","author_orcid":"0000-0002-6939-7718"}},{"author":{"name":"Asada H","author_orcid":null}},{"author":{"name":"Iwata S","author_orcid":null}}],"cross_references":["EMD-33785","EMD-33786"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Im D","author_orcid":"0000-0002-6939-7718"},{"name":"Kishikawa JI","author_orcid":"0000-0003-3913-7330"},{"name":"Shiimura Y","author_orcid":null},{"name":"Hisano H","author_orcid":null},{"name":"Ito A","author_orcid":null},{"name":"Fujita-Fujiharu Y","author_orcid":"0000-0002-2411-5473"},{"name":"Sugita Y","author_orcid":"0000-0001-6861-4840"},{"name":"Noda T","author_orcid":null},{"name":"Kato T","author_orcid":"0000-0002-8879-6685"},{"name":"Asada H","author_orcid":"0000-0001-6255-4728"},{"name":"Iwata S","author_orcid":"0000-0003-1735-2937"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural insights into the agonists binding and receptor selectivity of human histamine H<sub>4</sub> receptor","volume":"14","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1038/s41467-023-42260-z","pubmedid":"37863901","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"3.1 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7yfc","7yfd"],"entry_doi":"10.6019/EMPIAR-11708"}}