{"EMPIAR-11704":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of ATTRV122I amyloid fibrils","directory":"data/Micrographs_raw_V122I","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2068,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":1.04,"pixel_height":1.04,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Krios1 Quantum-K2\nCs 2.7\n300kV EFTEM nanpprobe\nx130k spot 8 beam size 650nm\nc2=50  objective_aperture=100\n\nGIF-K2 counting\n10s exposure 40 frames\ntotal dose at the sample 57.70e/A2 --> dose per frame 1.4425\n1 pixel = 1.04A\ndose rate ~3-4 e/pix/s \n\n\ndefocus range -1.2 to -2.5","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[{"funding_body":"German Research Foundation (DFG)","code":"FA 456/28","country":"Germany"}],"version_history":[],"title":"ATTRV122I amyloid fibrils from hereditary ATTR amloidosis","principal_investigator":[{"author_orcid":"0000-0003-2123-6816","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","telephone":null,"fax":null,"first_name":"Marcus","last_name":"Fändrich","email":"marcus.faendrich [at] uni-ulm.de","country":"Germany","entry":"EMPIAR-11704"}],"status":"REL","deposition_date":"2023-06-29","release_date":"2023-12-18","obsolete_date":null,"update_date":"2023-12-18","corresponding_author":{"author":{"author_orcid":"0000-0002-9442-460X","middle_name":null,"organization":"Institut für Proteinbiochemie, Universität Ulm","street":"8/1 Helmholtzstrasse","town_or_city":"Ulm","state_or_province":"Baden Württemberg","post_or_zip":"89081","first_name":"Matthias","last_name":"Schmidt","country":"Germany"}},"authors":[{"author":{"name":"Steinebrei M","author_orcid":"0000-0002-0582-3909"}},{"author":{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"}},{"author":{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}}],"cross_references":["EMD-17738"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Steinebrei M","author_orcid":"0000-0002-0582-3909"},{"name":"Baur J","author_orcid":null},{"name":"Pradhan A","author_orcid":null},{"name":"Kupfer N","author_orcid":null},{"name":"Wiese S","author_orcid":"0000-0001-5697-2608"},{"name":"Hegenbart U","author_orcid":"0000-0003-1917-6746"},{"name":"Schönland SO","author_orcid":"0000-0002-4853-5579"},{"name":"Schmidt M","author_orcid":"0000-0002-9442-460X"},{"name":"Fändrich M","author_orcid":"0000-0003-2123-6816"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis","volume":"14","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1038/s41467-023-43301-3","pubmedid":"37993462","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"644.5 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8pkg"],"entry_doi":"10.6019/EMPIAR-11704"}}