{"EMPIAR-11680":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of amyloid fibrils extracted from the tg-SwDI mouse model","directory":"data","category":"micrographs - multiframe","header_format":"EER","data_format":"EER","num_images_or_tilt_series":25662,"frames_per_image":700,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.808,"pixel_height":0.808,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The files are unaligned multi-frame movies. The data was collected in EER format with 700 camera frames (total dose of 40.1 electrons per squared Angstrom in a 2.91s exposure).","image_width":"4096","image_height":"4096"}],"workflow_file":null,"grant_references":[{"funding_body":"German Federal Ministry for Education and Research","code":"16LW028","country":"Germany"}],"version_history":[],"title":"Single particle cryo-EM dataset of sarkosyl-insoluble fraction from tg-SwDI mouse mouse brain tissue containing amyloid-beta fibrils","principal_investigator":[{"author_orcid":"0000-0003-1803-5431","middle_name":"F","organization":"Institute of Biological Information Processing, Structural Biochemistry (IBI-7), Forschungszentrum Jülich, Jülich, Germany","street":"Wilhelm-Johnen-Straße","town_or_city":"Jülich","state_or_province":"North Rhine-Westphalia","post_or_zip":"52428","telephone":null,"fax":null,"first_name":"Gunnar","last_name":"Schröder","email":"gu.schroeder [at] fz-juelich.de","country":"Germany","entry":"EMPIAR-11680"}],"status":"REL","deposition_date":"2023-08-04","release_date":"2025-07-16","obsolete_date":null,"update_date":"2025-07-16","corresponding_author":{"author":{"author_orcid":"0000-0003-1803-5431","middle_name":"F","organization":"Institute of Biological Information Processing, Structural Biochemistry (IBI-7), Forschungszentrum Jülich, Jülich, Germany","street":"Wilhelm-Johnen-Straße","town_or_city":"Jülich","state_or_province":"North Rhine-Westphalia","post_or_zip":"52428","first_name":"Gunnar","last_name":"Schröder","country":"Germany"}},"authors":[{"author":{"name":"Zielinski M","author_orcid":"0000-0001-7443-917X"}},{"author":{"name":"Peralta Reyes FS","author_orcid":"0000-0001-8379-4827"}},{"author":{"name":"Gremer L","author_orcid":"0000-0001-7065-5027"}},{"author":{"name":"Schemmert S","author_orcid":"0000-0002-7228-2700"}},{"author":{"name":"Frieg B","author_orcid":"0000-0002-7877-0262"}},{"author":{"name":"Schäfer LU","author_orcid":"0000-0002-8481-6298"}},{"author":{"name":"Willuweit A","author_orcid":"0000-0002-6725-0755"}},{"author":{"name":"Donner L","author_orcid":"0000-0002-3997-1117"}},{"author":{"name":"Elvers M","author_orcid":"0000-0002-3234-9341"}},{"author":{"name":"Nilsson LNG","author_orcid":"0000-0002-8362-1042"}},{"author":{"name":"Syvänen S","author_orcid":"0000-0002-8196-4041"}},{"author":{"name":"Sehlin D","author_orcid":"0000-0002-9430-3859"}},{"author":{"name":"Ingelsson M","author_orcid":"0000-0001-5466-8370"}},{"author":{"name":"Willbold D","author_orcid":"0000-0002-0065-7366"}},{"author":{"name":"Schröder GF","author_orcid":"0000-0003-1803-5431"}}],"cross_references":["EMD-16957","EMD-16959","EMD-16961"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Zielinski M","author_orcid":"0000-0001-7443-917X"},{"name":"Peralta Reyes FS","author_orcid":"0000-0001-8379-4827"},{"name":"Gremer L","author_orcid":"0000-0001-7065-5027"},{"name":"Schemmert S","author_orcid":null},{"name":"Frieg B","author_orcid":"0000-0002-7877-0262"},{"name":"Schäfer LU","author_orcid":null},{"name":"Willuweit A","author_orcid":"0000-0002-6725-0755"},{"name":"Donner L","author_orcid":null},{"name":"Elvers M","author_orcid":null},{"name":"Nilsson LNG","author_orcid":"0000-0002-8362-1042"},{"name":"Syvänen S","author_orcid":"0000-0002-8196-4041"},{"name":"Sehlin D","author_orcid":"0000-0002-9430-3859"},{"name":"Ingelsson M","author_orcid":null},{"name":"Willbold D","author_orcid":"0000-0002-0065-7366"},{"name":"Schröder GF","author_orcid":"0000-0003-1803-5431"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM of Aβ fibrils from mouse models find tg-APP<sub>ArcSwe</sub> fibrils resemble those found in patients with sporadic Alzheimer's disease","volume":"26","country":"United Kingdom","first_page":"2073","last_page":"2080","year":"2023","language":"English","doi":"10.1038/s41593-023-01484-4","pubmedid":"37973869","details":"The files are unaligned multi-frame movies. The data was collected in EER format with 700 camera frames (total dose of 40.1 electrons per squared Angstrom in a 2.91s exposure).","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature neuroscience","journal_abbreviation":"Nat Neurosci","issue":"12","preprint":false}],"dataset_size":"11.2 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8olg","8oln","8olq"],"entry_doi":"10.6019/EMPIAR-11680"}}