{"EMPIAR-11656":{"imagesets":[{"segmentations":[],"name":"Unaligned, gain-corrected micrographs of mitochondrial complex I from mouse heart inhibited with IACS-2858","directory":"data","category":"micrographs - multiframe","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":571,"frames_per_image":25,"frame_range_min":1,"frame_range_max":25,"voxel_type":"32 BIT FLOAT","pixel_width":1.055,"pixel_height":1.055,"micrographs_file_pattern":"data/*.mrc","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Micrographs are the average of 25 unaligned, gain-corrected frames. Images were collected on a Krios with a K2 detector and energy filter with a slit width of 20eV. Data were collected over 10 seconds with a dose rate of 5.84 e / A-2 / s with a total dose of 58.4 e/A-2.","image_width":"3838","image_height":"3710"}],"workflow_file":null,"grant_references":[{"funding_body":"Medical Research Council (MRC, United Kingdom)","code":"MC_UU_00015/2","country":"United Kingdom"},{"funding_body":"Medical Research Council (MRC, United Kingdom)","code":"MC_U105663141","country":"United Kingdom"}],"version_history":[],"title":"Single particle cryo-EM dataset of mitochondrial complex I from Mus musculus inhibited by IACS-2858 - 2","principal_investigator":[{"author_orcid":"0000-0001-8667-6797","middle_name":null,"organization":"MRC Mitochondrial Biology Unit","street":"Hills Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0XY","telephone":null,"fax":null,"first_name":"Judy","last_name":"Hirst","email":"jh480 [at] cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-11656"}],"status":"REL","deposition_date":"2023-08-04","release_date":"2023-10-03","obsolete_date":null,"update_date":"2023-10-03","corresponding_author":{"author":{"author_orcid":"0000-0001-6890-6050","middle_name":"Ruth","organization":"MRC Mitochondrial Biology Unit","street":"Hills Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0XY","first_name":"Hannah","last_name":"Bridges","country":"United Kingdom"}},"authors":[{"author":{"name":"Chung I","author_orcid":"0000-0002-2902-4677"}},{"author":{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}}],"cross_references":["EMD-12095"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Chung I","author_orcid":"0000-0002-2902-4677"},{"name":"Serreli R","author_orcid":null},{"name":"Cross JB","author_orcid":null},{"name":"Di Francesco ME","author_orcid":null},{"name":"Marszalek JR","author_orcid":null},{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.","volume":"7","country":"","first_page":null,"last_page":null,"year":"2021","language":"English","doi":"10.1126/sciadv.abg4000","pubmedid":"33990335","details":"571 gain-corrected mrc movies containing 25 frames with a total dose of 58.4 e/A^2","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science advances","journal_abbreviation":"Sci Adv","issue":"20","preprint":false}],"dataset_size":"757.2 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7b93"],"entry_doi":"10.6019/EMPIAR-11656"}}