{"EMPIAR-11647":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of human DNA polymerase alpha-primase","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7014,"frames_per_image":45,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":1.066,"pixel_height":1.066,"micrographs_file_pattern":"data/FoilHole_*_fractions.tiff","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Micrographs were imaged using Gatan K3 camera, each with 45 movie frames using the FEI EPU software with aberration-free image shift. The calibrated pixel size was 1.066 Å, and the total electron dose was 50.50 electrons Å-2 for each micrograph.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"Wellcome Trust","code":"221892/Z/20/Z","country":"United Kingdom"}],"version_history":[],"title":"Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 2 to 4 and initiation","principal_investigator":[{"author_orcid":"0000-0002-9300-497X","middle_name":null,"organization":"University of Cambridge","street":"Sanger Building, 80 Tennis Ct Rd, Cambridge CB2 1GA","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 1GA","telephone":null,"fax":null,"first_name":"Luca","last_name":"Pellegrini","email":"lp212 [at] cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-11647"}],"status":"REL","deposition_date":"2023-08-02","release_date":"2024-07-03","obsolete_date":null,"update_date":"2024-07-03","corresponding_author":{"author":{"author_orcid":"0000-0002-3846-0147","middle_name":null,"organization":"Department of Biochemistry, University of Cambridge","street":"Sanger Building, 80 Tennis Ct Rd","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 1GA","first_name":"Zhan","last_name":"Yin","country":"United Kingdom"}},"authors":[{"author":{"name":"Yin Z","author_orcid":"0000-0002-3846-0147"}}],"cross_references":["EMD-17807","EMD-17812","EMD-17810","EMD-17811"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Yin Z","author_orcid":null},{"name":"Kilkenny ML","author_orcid":null},{"name":"Ker DS","author_orcid":null},{"name":"Pellegrini L","author_orcid":null}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"CryoEM insights into RNA primer synthesis by the human primosome","volume":null,"country":"United Kingdom","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":false}],"dataset_size":"1.7 TB","experiment_type":"EMDB","scale":"molecule","entry_doi":"10.6019/EMPIAR-11647"}}