{"EMPIAR-11605":{"imagesets":[{"segmentations":[],"name":"Motion corrected, dose-weighted micgrographs","directory":"data","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":5958,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.155,"pixel_height":1.155,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"This is a dataset of the AP2 clathrin adaptor bound to a Y-cargo motif from Tgn38 in the presence of heparin. Included are motion-corrected and dose-weighted micrographs processed using cryoSPARC v3.\n\nTotal movies: 5958\nPixel Size: 1.155 Ang\nTotal dose: 55 e-/A2","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[{"funding_body":"National Institutes of Health (NIH)","code":"R01GM127548","country":"United States"}],"version_history":[],"title":"AP2 bound to Y-cargo motif of Tgn38 in the presence of heparin","principal_investigator":[{"author_orcid":"0000-0003-1136-6000","middle_name":"Wayne","organization":"University of North Carolina at Chapel Hill","street":"3049E Genetic Medicine Bldg","town_or_city":"Chapel Hill","state_or_province":"NC","post_or_zip":"27599","telephone":"9198439585","fax":null,"first_name":"Richard","last_name":"Baker","email":"baker [at] med.unc.edu","country":"United States","entry":"EMPIAR-11605"}],"status":"REL","deposition_date":"2023-06-30","release_date":"2023-08-20","obsolete_date":null,"update_date":"2023-08-20","corresponding_author":{"author":{"author_orcid":"0000-0003-1136-6000","middle_name":"Wayne","organization":"University of North Carolina at Chapel Hill","street":"3049A Genetic Medicine Bldg","town_or_city":"Chapel Hill","state_or_province":"NC","post_or_zip":"27599","first_name":"Richard","last_name":"Baker","country":"United States"}},"authors":[{"author":{"name":"Partlow EA","author_orcid":"0000-0001-5513-088X"}},{"author":{"name":"Cannon KS","author_orcid":"0000-0002-6648-3442"}},{"author":{"name":"Hollopeter G","author_orcid":"0000-0002-6409-0530"}},{"author":{"name":"Baker RW","author_orcid":"0000-0003-1136-6000"}}],"cross_references":["EMD-24712"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Partlow EA","author_orcid":"0000-0001-5513-088X"},{"name":"Cannon KS","author_orcid":"0000-0002-6648-3442"},{"name":"Hollopeter G","author_orcid":"0000-0002-6409-0530"},{"name":"Baker RW","author_orcid":"0000-0003-1136-6000"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization","volume":"29","country":"","first_page":"339","last_page":"347","year":"2022","language":"English","doi":"10.1038/s41594-022-00749-z","pubmedid":"35347313","details":"The data are motion corrected and dose-weighted micrographs from dose-fractionated stacks collected on a Talos Arctica with a K3 DED. There are 60 frames, with a pixel size of 1.155 Angstrom, and a total dose of 55 e-/A^2. These micrographs were used to determine a structure of AP2 bound to the Y-cargo motif of Tgn38 in the presence of heparin.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature structural & molecular biology","journal_abbreviation":"Nat Struct Mol Biol","issue":"4","preprint":false}],"dataset_size":"523.1 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7rwa"],"entry_doi":"10.6019/EMPIAR-11605"}}