{"EMPIAR-11527":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of wild-type mouse mitochondrial complex I from an as-prepared sample solubilised in DDM","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2674,"frames_per_image":40,"frame_range_min":1,"frame_range_max":40,"voxel_type":"UNSIGNED BYTE","pixel_width":0.5125,"pixel_height":0.5125,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The sample was frozen on PEGylated gold grids. Images were saved in super-resolution (11,520 x 8,184) at a value of 0.5125 Å but we later determined it to be 0.534 Å via calibration to previously obtained data and built models. The gain reference file (gainreference.mrc) and detector defects file (Defects.txt) are also uploaded.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[{"funding_body":"Medical Research Council (MRC, United Kingdom)","code":"MC_UU_00015/2","country":"United Kingdom"},{"funding_body":"Medical Research Council (MRC, United Kingdom)","code":"MC_UU_00028/1","country":"United Kingdom"}],"version_history":[],"title":"Single particle cryo-EM dataset of Mus musculus mitochondrial complex I","principal_investigator":[{"author_orcid":"0000-0001-8667-6797","middle_name":null,"organization":"MRC mitochondrial Biology Unit, University of Cambridge","street":"The Keith Peters Building, Cambridge Biomedical Campus, Hills Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0XY","telephone":null,"fax":null,"first_name":"Judy","last_name":"Hirst","email":"jh [at] mrc-mbu.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-11527"}],"status":"REL","deposition_date":"2023-04-24","release_date":"2023-08-18","obsolete_date":null,"update_date":"2023-08-18","corresponding_author":{"author":{"author_orcid":"0000-0001-8667-6797","middle_name":null,"organization":"MRC mitochondrial Biology Unit, University of Cambridge","street":"The Keith Peters Building, Cambridge Biomedical Campus, Hills Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0XY","first_name":"Judy","last_name":"Hirst","country":"United Kingdom"}},"authors":[{"author":{"name":"Grba DN","author_orcid":"0000-0003-2915-951X"}},{"author":{"name":"Chung I","author_orcid":"0000-0002-2902-4677"}},{"author":{"name":"Bridges HR","author_orcid":"0000-0001-6890-6050"}},{"author":{"name":"Agip AA","author_orcid":"0000-0002-3020-8262"}},{"author":{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}}],"cross_references":["EMD-16965"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Grba DN","author_orcid":"0000-0003-2915-951X"},{"name":"Chung I","author_orcid":"0000-0002-2902-4677"},{"name":"Bridges HR","author_orcid":"0000-0001-6890-6050"},{"name":"Agip AA","author_orcid":"0000-0002-3020-8262"},{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I","volume":"9","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1126/sciadv.adi1359","pubmedid":"37531432","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science advances","journal_abbreviation":"Sci Adv","issue":"31","preprint":false}],"dataset_size":"1.1 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8om1"],"entry_doi":"10.6019/EMPIAR-11527"}}