{"EMPIAR-11441":{"imagesets":[{"segmentations":[],"name":"FMC63-CD19 dataset1","directory":"data/dataset1_22feb04a","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":489,"frames_per_image":48,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.548,"pixel_height":0.548,"micrographs_file_pattern":"data/dataset1_22feb04a/*tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Arctica operated at 200 kV with a GatanK3 imaging system collected at 36,000X nominal magnification. The calibrated pixel size of 0.5480 Å was used for processing.\nMovies were collected using Leginon (Suloway et al., 2005) at a dose rate of 21.17 e-/Å2/s with a total exposure of 2.40 seconds, for an accumulated dose of 50.82 e-/Å2. Intermediate frames were recorded every 0.05 seconds for a total of 48 frames per micrograph.","image_width":"11520","image_height":"8184"},{"segmentations":[],"name":"FMC63-CD19 dataset2","directory":"data/dataset2_22mar07c","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1910,"frames_per_image":48,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.548,"pixel_height":0.548,"micrographs_file_pattern":"data/dataset2_22mar07c/*tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Arctica operated at 200 kV with a GatanK3 imaging system collected at 36,000X nominal magnification. The calibrated pixel size of 0.5480 Å was used for processing.\nMovies were collected using Leginon (Suloway et al., 2005) at a dose rate of 21.00 e-/Å2/s with a total exposure of 2.40 seconds, for an accumulated dose of 50.40 e-/Å2. Intermediate frames were recorded every 0.05 seconds for a total of 48 frames per micrograph.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"FMC63 scFv in complex with soluble CD19","principal_investigator":[{"author_orcid":"0000-0002-6127-0093","middle_name":"R","organization":"Department of Physiology and Biophysics, Weill Cornell Medical College","street":null,"town_or_city":"New York","state_or_province":"New York","post_or_zip":"10065","telephone":null,"fax":null,"first_name":"Joel","last_name":"Meyerson","email":"joel.meyerson [at] gmail.com","country":"United States","entry":"EMPIAR-11441"}],"status":"REL","deposition_date":"2023-01-16","release_date":"2023-03-17","obsolete_date":null,"update_date":"2023-03-17","corresponding_author":{"author":{"author_orcid":"0000-0002-6127-0093","middle_name":"R","organization":"Department of Physiology and Biophysics, Weill Cornell Medical College","street":null,"town_or_city":"New York","state_or_province":"New York","post_or_zip":"10065","first_name":"Joel","last_name":"Meyerson","country":"United States"}},"authors":[{"author":{"name":"Meyerson JR","author_orcid":"0000-0002-6127-0093"}},{"author":{"name":"He C","author_orcid":"0000-0001-8181-2104"}}],"cross_references":["EMD-26719"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"He C","author_orcid":"0000-0001-8181-2104"},{"name":"Mansilla-Soto J","author_orcid":"0000-0003-2889-1397"},{"name":"Khanra N","author_orcid":"0000-0003-4217-1273"},{"name":"Hamieh M","author_orcid":null},{"name":"Bustos V","author_orcid":null},{"name":"Paquette AJ","author_orcid":null},{"name":"Garcia Angus A","author_orcid":"0000-0001-6061-8513"},{"name":"Shore DM","author_orcid":"0000-0002-8845-6285"},{"name":"Rice WJ","author_orcid":"0000-0002-5187-255X"},{"name":"Khelashvili G","author_orcid":null},{"name":"Sadelain M","author_orcid":"0000-0002-9031-8025"},{"name":"Meyerson JR","author_orcid":"0000-0002-6127-0093"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"CD19 CAR antigen engagement mechanisms and affinity tuning","volume":"8","country":"","first_page":null,"last_page":null,"year":"2023","language":"English","doi":"10.1126/sciimmunol.adf1426","pubmedid":"36867678","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Science immunology","journal_abbreviation":"Sci Immunol","issue":"81","preprint":false}],"dataset_size":"1.4 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7urv"],"entry_doi":"10.6019/EMPIAR-11441"}}