{"EMPIAR-11375":{"imagesets":[{"segmentations":[],"name":"D-cycloserine and glutamate bound human GluN1a-GluN2C NMDA receptor","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":15350,"frames_per_image":30,"frame_range_min":1,"frame_range_max":30,"voxel_type":"UNSIGNED BYTE","pixel_width":0.856,"pixel_height":0.856,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"4092","image_height":"5760"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"D-cycloserine and glutamate bound human GluN1a-GluN2C NMDA receptor","principal_investigator":[{"author_orcid":"0000-0001-8296-8426","middle_name":null,"organization":"Cold Spring Harbor Laboratory","street":"1 Bungtown Rd","town_or_city":"Cold Spring Harbor","state_or_province":"NY","post_or_zip":"11724","telephone":null,"fax":null,"first_name":"Hiro","last_name":"Furukawa","email":"furukawa [at] cshl.edu","country":"United States","entry":"EMPIAR-11375"}],"status":"REL","deposition_date":"2023-01-14","release_date":"2023-02-06","obsolete_date":null,"update_date":"2023-02-06","corresponding_author":{"author":{"author_orcid":"0000-0001-6154-6283","middle_name":null,"organization":"Cold Spring Harbor Laboratory","street":"1 Bungtown Rd","town_or_city":"Cold Spring Harbor","state_or_province":"New York","post_or_zip":"11724","first_name":"Tsung Han","last_name":"Chou","country":"United States"}},"authors":[{"author":{"name":"Chou TH","author_orcid":"0000-0001-6154-6283"}}],"cross_references":["EMD-27953","EMD-27954"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Chou TH","author_orcid":"0000-0001-6154-6283"},{"name":"Kang H","author_orcid":null},{"name":"Simorowski N","author_orcid":null},{"name":"Traynelis SF","author_orcid":"0000-0002-3750-9615"},{"name":"Furukawa H","author_orcid":"0000-0001-8296-8426"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs","volume":"82","country":"United States","first_page":"4548","last_page":"4563","year":"2022","language":"English","doi":"10.1016/j.molcel.2022.10.008","pubmedid":"36309015","details":"Structural and functional analysis of human GluN2C- and GluN2D-containing N-methyl-D-aspartate receptors. The results reveal unique inter-subunit and domain arrangements of the GluN2C containing NMDARs. These features explain the mechanism of the binding of the GluN2C specific positive allosteric modulator, PYD-106.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Molecular Cell","journal_abbreviation":"Mol Cell","issue":"23","preprint":false}],"dataset_size":"2.9 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8e92","8e93"],"entry_doi":"10.6019/EMPIAR-11375"}}