{"EMPIAR-11193":{"imagesets":[{"segmentations":[],"name":"Aligned multi-frame micrographs","directory":"data","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":3577,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.88,"pixel_height":0.88,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The micrographs are dose weighted motion corrected with a total electron exposure of 47e/A2","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"CryoEM structure of hM3Dq-miniGq in complex with CNO","principal_investigator":[{"author_orcid":"0000-0002-0561-6520","middle_name":"L","organization":"UNC Department of Pharmacology","street":"4072 Genetic Medicine Building","town_or_city":"Chapel Hill","state_or_province":"NC","post_or_zip":"27514","telephone":"919-966-7535","fax":null,"first_name":"Bryan","last_name":"Roth","email":"bryan_roth [at] med.unc.edu","country":"United States","entry":"EMPIAR-11193"}],"status":"REL","deposition_date":"2022-08-31","release_date":"2022-12-09","obsolete_date":null,"update_date":"2022-12-09","corresponding_author":{"author":{"author_orcid":"0000-0003-1822-2384","middle_name":"Firoze","organization":"University of Maryland, Baltimore","street":"108 Greene St","town_or_city":"Baltimore","state_or_province":"MD","post_or_zip":"27599","first_name":"Jonathan","last_name":"Fay","country":"United States"}},"authors":[{"author":{"name":"Fay J","author_orcid":"0000-0003-1822-2384"}},{"author":{"name":"Roth B","author_orcid":"0000-0002-0561-6520"}},{"author":{"name":"Zhang S","author_orcid":"0000-0002-5245-443X"}}],"cross_references":["EMD-27968"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Zhang S","author_orcid":"0000-0002-5245-443X"},{"name":"Gumpper RH","author_orcid":null},{"name":"Huang XP","author_orcid":null},{"name":"Liu Y","author_orcid":"0000-0002-8649-7892"},{"name":"Krumm BE","author_orcid":"0000-0001-6039-4767"},{"name":"Cao C","author_orcid":"0000-0003-4017-741X"},{"name":"Fay JF","author_orcid":"0000-0003-1822-2384"},{"name":"Roth BL","author_orcid":"0000-0002-0561-6520"}],"editors":[{"name":" ","author_orcid":null}],"published":true,"j_or_nj_citation":true,"title":"Molecular basis for selective activation of DREADD-based chemogenetics","volume":"612","country":"","first_page":"354","last_page":"362","year":"2022","language":"English","doi":"10.1038/s41586-022-05489-0","pubmedid":"36450989","details":"The micrographs are dose weighted motion corrected 60 frame movies collected on a 200 kV ThermoFisher Scientific G3 Talos Arctica equipped with a Gatan K3 direct-electron detector (total exposure dose ~47 e/A^2, 0.88 raw pixel size)","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":null,"preprint":false}],"dataset_size":"314.1 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["8e9y"],"entry_doi":"10.6019/EMPIAR-11193"}}