{"EMPIAR-11095":{"imagesets":[{"segmentations":[],"name":"Aligned averages of PMCA-amplified α-synuclein fibrils, Multiple System Atrophy patient-derived seeds","directory":"data/Micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":4474,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.05,"pixel_height":1.05,"micrographs_file_pattern":"data/Micrographs/*.mrc","picked_particles_file_pattern":"data/Coordinates/*_manualpick.star","picked_particles_directory":"data/Coordinates/","details":"Provided are aligned average micrographs collected on a Titan Krios at 300kV with a K3 detector operating in non-superresolution counting mode. Applied defocus values ranged from −0.7 to −2.9 µm. MotionCor2 was used to align 40 dose fractions that were taken with a total electron dose of ~43.1e-/Ų. Coordinates provided are of start-end pairs, for helical segmentation and extraction.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"PMCA-amplified α-synuclein fibrils, Multiple System Atrophy patient-derived seeds","principal_investigator":[{"author_orcid":"0000-0003-1803-5431","middle_name":"F","organization":"Forschungszentrum Jülich","street":null,"town_or_city":"Jülich","state_or_province":null,"post_or_zip":"52425","telephone":"+49 2461 61 3259","fax":null,"first_name":"Gunnar","last_name":"Schröder","email":"gu.schroeder [at] fz-juelich.de","country":"Germany","entry":"EMPIAR-11095"}],"status":"REL","deposition_date":"2021-06-29","release_date":"2022-07-27","obsolete_date":null,"update_date":"2022-07-27","corresponding_author":{"author":{"author_orcid":"0000-0003-3378-0683","middle_name":"Alexander","organization":"Forschungszentrum Jülich","street":null,"town_or_city":"Jülich","state_or_province":null,"post_or_zip":"52425","first_name":"James","last_name":"Geraets","country":"Germany"}},"authors":[{"author":{"name":"Frieg B","author_orcid":"0000-0002-7877-0262"}},{"author":{"name":"Geraets JA","author_orcid":"0000-0003-3378-0683"}},{"author":{"name":"Schröder GF","author_orcid":"0000-0003-1803-5431"}}],"cross_references":["EMD-13124"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Frieg B","author_orcid":"0000-0002-7877-0262"},{"name":"Geraets JA","author_orcid":"0000-0003-3378-0683"},{"name":"Strohäker T","author_orcid":null},{"name":"Dienemann C","author_orcid":null},{"name":"Mavroeidi P","author_orcid":"0000-0002-5460-2336"},{"name":"Jung BC","author_orcid":null},{"name":"Kim WS","author_orcid":null},{"name":"Lee SJ","author_orcid":null},{"name":"Xilouri M","author_orcid":"0000-0001-7038-0780"},{"name":"Zweckstetter M","author_orcid":"0000-0002-2536-6581"},{"name":"Schröder GF","author_orcid":"0000-0003-1803-5431"}],"editors":[],"published":false,"j_or_nj_citation":true,"title":"Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein","volume":null,"country":"","first_page":null,"last_page":null,"year":null,"language":null,"doi":null,"pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"","journal_abbreviation":"","issue":null,"preprint":true}],"dataset_size":"392.8 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7ozh"],"entry_doi":"10.6019/EMPIAR-11095"}}