{"EMPIAR-10980":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame cryo-EM micrographs of human somatic angiotensin I-converting enzyme in the apo state","directory":"data/micrographs","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":7689,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.53,"pixel_height":0.53,"micrographs_file_pattern":"data/micrographs/*st_384*/FoilHole_*_Data_*_*_2019*_*_fractions.tiff","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The 7689 raw unaligned micrograph movies are found in two subdirectories and each movie is composed of 40 movie frames (accumulating 43 electron per squared Angstrom in a 3 seconds exposure). Data was collected in super-resolution mode at 0.53 Angstrom per pixel (Cs: 2.7mm; Acceleration voltage: 300kV; Magnification: 81000x; Defocus: -1.8 to -3 micrometer). The gain.mrc file is included and should be applied (flip the gain image upside down).","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structures of monomeric and dimeric human somatic angiotensin I-converting enzyme (apo form)","principal_investigator":[{"author_orcid":"0000-0003-2032-7636","middle_name":null,"organization":"Department of Integrative Biomedical Sciences, University of Cape Town","street":null,"town_or_city":"Cape Town","state_or_province":null,"post_or_zip":"7925","telephone":null,"fax":null,"first_name":"Edward","last_name":"Sturrock","email":"edward.sturrock [at] uct.ac.za","country":"South Africa","entry":"EMPIAR-10980"}],"status":"REL","deposition_date":"2022-03-08","release_date":"2022-07-18","obsolete_date":null,"update_date":"2022-07-18","corresponding_author":{"author":{"author_orcid":"0000-0001-9905-1438","middle_name":null,"organization":"Department of Integrative Biomedical Sciences, University of Cape Town","street":null,"town_or_city":"Cape Town","state_or_province":null,"post_or_zip":"7925","first_name":"Lizelle","last_name":"Lubbe","country":"South Africa"}},"authors":[{"author":{"name":"Lubbe L","author_orcid":"0000-0001-9905-1438"}},{"author":{"name":"Sewell BT","author_orcid":"0000-0002-6701-2394"}},{"author":{"name":"Sturrock ED","author_orcid":"0000-0003-2032-7636"}}],"cross_references":["EMD-13801","EMD-13797","EMD-13804","EMD-13799","EMD-13803","EMD-13802"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Lubbe L","author_orcid":"0000-0001-9905-1438"},{"name":"Sewell BT","author_orcid":"0000-0002-6701-2394"},{"name":"Woodward JD","author_orcid":"0000-0002-7350-8302"},{"name":"Sturrock ED","author_orcid":"0000-0003-2032-7636"}],"editors":[{"name":" ","author_orcid":null}],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization","volume":null,"country":"","first_page":null,"last_page":null,"year":"2022","language":"English","doi":"10.15252/embj.2021110550","pubmedid":"35818993","details":"The publication has been peer-reviewed and is currently undergoing minor revision.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"The EMBO journal","journal_abbreviation":"EMBO J","issue":null,"preprint":false}],"dataset_size":"3.8 TB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7q4c","7q3y","7q4e","7q49","7q4d"],"entry_doi":"10.6019/EMPIAR-10980"}}