{"EMPIAR-10975":{"imagesets":[{"segmentations":[],"name":"Unaligned movies for E1-ATP state","directory":"data/Movies/Dataset0","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3114,"frames_per_image":48,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.83,"pixel_height":0.83,"micrographs_file_pattern":"data/Movies/Dataset0/tomita6_AMPPCP_*.tif","picked_particles_file_pattern":"data/Particles/dataset0_shiny.star","picked_particles_directory":"data/Particles/Dataset0","details":"","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Unaligned movies for E1P-ADP state","directory":"data/Movies/Dataset1","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3303,"frames_per_image":48,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.83,"pixel_height":0.83,"micrographs_file_pattern":"data/Movies/Dataset1/tomita2_Sp-AlFADP_*.tif","picked_particles_file_pattern":"data/Particles/dataset1_shiny.star","picked_particles_directory":"data/Particles/Dataset1","details":"","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Unaligned movies for SPM-bound E2P state","directory":"data/Movies/Dataset2","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3987,"frames_per_image":64,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.83,"pixel_height":0.83,"micrographs_file_pattern":"data/Movies/Dataset2/tomita0730_2-3_BeF-SP_1*.tif","picked_particles_file_pattern":"data/Particles/dataset2_shiny.star","picked_particles_directory":"data/Particles/Dataset2","details":"","image_width":"5760","image_height":"4092"},{"segmentations":[],"name":"Unaligned movies for SPM-bound E2Pi state","directory":"data/Movies/Dataset3","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3834,"frames_per_image":64,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.83,"pixel_height":0.83,"micrographs_file_pattern":"data/Movies/Dataset3/tomita0730_1-4_*.tif","picked_particles_file_pattern":"data/Particles/dataset3_shiny.star","picked_particles_directory":"data/Particles/Dataset3","details":"","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of the human ATP13A2","principal_investigator":[{"author_orcid":"0000-0003-1813-7008","middle_name":null,"organization":"Department of Biol. Sci., Univ. Tokyo","street":"7-3-1 Hongo,","town_or_city":"Bunkyo-ku","state_or_province":"Tokyo","post_or_zip":"113-0033","telephone":"+81 03 5841 4391","fax":null,"first_name":"Osamu","last_name":"Nureki","email":"nureki [at] bs.s.u-tokyo.ac.jp","country":"Japan","entry":"EMPIAR-10975"}],"status":"REL","deposition_date":"2022-02-16","release_date":"2022-05-17","obsolete_date":null,"update_date":"2022-05-17","corresponding_author":{"author":{"author_orcid":"0000-0003-1813-7008","middle_name":null,"organization":"Department of Biol. Sci., Univ. Tokyo","street":"7-3-1 Hongo,","town_or_city":"Bunkyo-ku","state_or_province":"Tokyo","post_or_zip":"113-0033","first_name":"Osamu","last_name":"Nureki","country":"Japan"}},"authors":[{"author":{"name":"Tomita A","author_orcid":"0000-0003-3887-1429"}},{"author":{"name":"Daiho T","author_orcid":"0000-0001-5707-6776"}},{"author":{"name":"Kusakizako T","author_orcid":"0000-0002-6186-6647"}},{"author":{"name":"Yamashita K","author_orcid":"0000-0002-5442-7582"}},{"author":{"name":"Ogasawara S","author_orcid":"0000-0001-6908-9953"}},{"author":{"name":"Murata T","author_orcid":"0000-0002-5748-4670"}},{"author":{"name":"Nishizawa T","author_orcid":"0000-0001-7463-8398"}},{"author":{"name":"Nureki O","author_orcid":"0000-0003-1813-7008"}}],"cross_references":["EMD-32069","EMD-32067","EMD-32068","EMD-32066"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Tomita A","author_orcid":"0000-0003-3887-1429"},{"name":"Daiho T","author_orcid":"0000-0001-5707-6776"},{"name":"Kusakizako T","author_orcid":"0000-0002-6186-6647"},{"name":"Yamashita K","author_orcid":"0000-0002-5442-7582"},{"name":"Ogasawara S","author_orcid":"0000-0001-6908-9953"},{"name":"Murata T","author_orcid":"0000-0002-5748-4670"},{"name":"Nishizawa T","author_orcid":"0000-0001-7463-8398"},{"name":"Nureki O","author_orcid":"0000-0003-1813-7008"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM reveals mechanistic insights into lipid-facilitated polyamine export by human ATP13A2","volume":"81","country":"United States","first_page":"4799","last_page":"4809.e5","year":"2021","language":"English","doi":"10.1016/j.molcel.2021.11.001","pubmedid":"34798056","details":"Movies were collected on Titan Krios G3i with Gatan K3. The calibrated pixel size for all datasets is 0.83 A. Four datasets were used to yield the structures.\n\nDataset 0: EMD-32066 (E1-ATP state)\nDataset 1: EMD-32067 (E1P-ADP state)\nDataset 2: EMD-32068 (SPM-bound E2P state)\nDataset 3: EMD-32069 (SPM-bound E2Pi state)\n\nDose rate (shown on SerialEM) is ~1 e/A2/frame.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Molecular cell","journal_abbreviation":"Mol Cell","issue":"23","preprint":false}],"dataset_size":"3.8 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["7vpl","7vpj","7vpk","7vpi"],"entry_doi":"10.6019/EMPIAR-10975"}}