{"EMPIAR-10972":{"imagesets":[{"segmentations":[],"name":"Representative cryoSXT datasets for studying changes to cellular compartments during HSV-1 infection of U2OS cells","directory":"data","category":"reconstructed volumes","header_format":"TIFF","data_format":"MRC","num_images_or_tilt_series":14,"frames_per_image":601,"frame_range_min":1,"frame_range_max":601,"voxel_type":"UNSIGNED BYTE","pixel_width":100.0,"pixel_height":100.0,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Representative tomograms from the manuscript \"Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of cytoplasmic vesicles and mitochondria during HSV-1 infection\" can be found in the hsv_remodelling directory (5 GB).\n\nDOI: 10.1101/2021.10.11.463900\n\nhsv_perinuclear_viral_particle_hff-htert/\nKLN_Dec2018_Box14_Grid2_D3F.SXT.FOV1.rec\n\nearly_stage_hsv_u2os/SXT/\nKLN_July2020_Box1G2_B1F.SXT.FOV3.rec\t\nKLN_July2020_Box1G2_D3A.SXT.FOV1.rec\n\nhsv_cell_surface_viral_particles_hff-htert/SXT/\nKLN_Feb2019_Feb2_Grid3_E3C.SXT.FOV1.rec\n\nhsv_cytoplasmic_viral_particles_hff-htert/SXT/\nKLN_Dec2018_Box12_Grid2_E4D.SXT.FOV2.rec\n\nhsv_nuclear_capsids_hff-htert/SXT/\nKLN_Feb2019_Feb2G1_D4F.SXT.FOV1.rec\n\nlate_stage_hsv_u2os/SXT/\nBoxK1p3_Grid4_E5D.SXT.FOV2.rec\nKLN_July2020_Box8G1_E2E.SXT.FOV2.rec\n\nuninfected_u2os/SXT/\nBoxK1p1_Grid2_A4B.SXT.FOV5.rec\nKLN_July2020_Box2_G2_F5A.SXT.FOV1.rec\n\nTomograms from Supplementary figure 1 of the manuscript \"Contour, a semi-automated segmentation and quantitation tool for cryo-soft-X-ray tomography\" can be found in the contour_supplementary_figure directory (4.9GB).\n\nDOI: 10.1101/2021.12.03.470962\n\nHFF-hTERT/SXT/\nKLN_Oct2020_Box8G2_E1C.SXT.FOV1.rec\n\nHaCaT/SXT/\nKLN_Jun2018_Box8G2_E5A.SXT.FOV1.rec\n\nU2OS/SXT/\nKLN_July2020_Box9G3_D5C.SXT.FOV1.rec\n\nVero/SXT/\nNV_Box3G3_B3D.SXT.FOV1.rec","image_width":"946","image_height":"946"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Representative data from Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of cytoplasmic vesicles and mitochondria during HSV-1 infection","principal_investigator":[{"author_orcid":"0000-0003-4547-4034","middle_name":"C","organization":"Department of Pathology, University of Cambridge","street":"Tennis Court Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 1QP","telephone":null,"fax":null,"first_name":"Stephen","last_name":"Graham","email":"scg34 [at] cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10972"},{"author_orcid":"0000-0001-9918-9998","middle_name":"M","organization":"Department of Pathology, University of Cambridge","street":"Tennis Court Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 1QP","telephone":null,"fax":null,"first_name":"Colin","last_name":"Crump","email":"cmc56 [at] cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10972"},{"author_orcid":"0000-0001-8091-9057","middle_name":null,"organization":"B24, Diamond Light Source","street":"Fermi Avenue","town_or_city":"Didcot","state_or_province":"Oxfordshire","post_or_zip":"OX11 0DE","telephone":null,"fax":null,"first_name":"Maria","last_name":"Harkiolaki","email":"maria.harkiolaki [at] diamond.ac.uk","country":"United Kingdom","entry":"EMPIAR-10972"}],"status":"REL","deposition_date":"2021-11-17","release_date":"2022-03-28","obsolete_date":null,"update_date":"2022-03-28","corresponding_author":{"author":{"author_orcid":"0000-0003-4547-4034","middle_name":"C","organization":"Department of Pathology, University of Cambridge","street":"Tennis Court Road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 1QP","first_name":"Stephen","last_name":"Graham","country":"United Kingdom"}},"authors":[{"author":{"name":"Nahas KLN","author_orcid":"0000-0003-3501-8473"}},{"author":{"name":"Connor VC","author_orcid":null}},{"author":{"name":"Scherer KM","author_orcid":"0000-0002-2042-5407"}},{"author":{"name":"Kaminski CF","author_orcid":"0000-0002-5194-0962"}},{"author":{"name":"Harkiolaki M","author_orcid":"0000-0001-8091-9057"}},{"author":{"name":"Crump CM","author_orcid":"0000-0001-9918-9998"}},{"author":{"name":"Graham SC","author_orcid":"0000-0003-4547-4034"}}],"cross_references":[],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Nahas KLN","author_orcid":"0000-0003-3501-8473"},{"name":"Connor VC","author_orcid":null},{"name":"Harkiolaki M","author_orcid":"0000-0001-8091-9057"},{"name":"Crump CM","author_orcid":"0000-0001-9918-9998"},{"name":"Graham SC","author_orcid":"0000-0003-4547-4034"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of cytoplasmic vesicles and mitochondria during HSV-1 infection","volume":null,"country":"United Kingdom","first_page":null,"last_page":null,"year":"2021","language":null,"doi":"10.1101/2021.10.11.463900","pubmedid":null,"details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"bioRxiv","journal_abbreviation":"","issue":null,"preprint":true}],"dataset_size":"9.9 GB","experiment_type":"SXT","scale":null,"entry_doi":"10.6019/EMPIAR-10972"}}