{"EMPIAR-10924":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of apo microtubule bound C-terminus of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T)","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2379,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":1.16,"pixel_height":1.16,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Contains data collected from 2 grids (19dec14f and 20aug12b). Each folder contains its own gain reference with the \"_norm.mrc\" suffix found in the references folder. Blank dark references are also included but are not needed for correction. Gain correction in cryosparc should work with default settings, while for motioncor2, please flip the image and apply no rotation.\nTotal dose is 55 e/A-2","image_width":"3710","image_height":"3838"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Apo C-terminal half of LRRK2 (I2020T) bound to microtubule","principal_investigator":[{"author_orcid":"0000-0002-7732-7023","middle_name":null,"organization":"CMM, UCSD","street":"9500 Gilman Dr, MC 0694","town_or_city":"La Jolla","state_or_province":"California","post_or_zip":"92093","telephone":null,"fax":null,"first_name":"Andres","last_name":"Leschziner","email":"aleschziner [at] ucsd.edu","country":"United States","entry":"EMPIAR-10924"}],"status":"REL","deposition_date":"2022-01-08","release_date":"2023-01-03","obsolete_date":null,"update_date":"2023-01-03","corresponding_author":{"author":{"author_orcid":"0000-0003-1033-9270","middle_name":null,"organization":"CMM, UCSD","street":"9500 Gilman Dr, MC 0694","town_or_city":"La Jolla","state_or_province":"California","post_or_zip":"92093","first_name":"Mariusz","last_name":"Matyszewski","country":"United States"}},"authors":[{"author":{"name":"Matyszewski M","author_orcid":"0000-0003-1033-9270"}},{"author":{"name":"Leschziner AE","author_orcid":"0000-0002-7732-7023"}}],"cross_references":["EMD-25674"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Snead DM","author_orcid":"0000-0001-7839-452X"},{"name":"Matyszewski M","author_orcid":"0000-0003-1033-9270"},{"name":"Dickey AM","author_orcid":"0000-0001-8725-0982"},{"name":"Lin YX","author_orcid":"0000-0002-1016-4776"},{"name":"Leschziner AE","author_orcid":"0000-0002-7732-7023"},{"name":"Reck-Peterson SL","author_orcid":"0000-0002-1553-465X"}],"editors":[{"name":" ","author_orcid":null}],"published":true,"j_or_nj_citation":true,"title":"Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules","volume":"29","country":"","first_page":"1196","last_page":"1207","year":"2022","language":"English","doi":"10.1038/s41594-022-00863-y","pubmedid":"36510024","details":"Publication includes structures of the C-terminal half of LRRK2 (I2020T) bound to microtubules as filaments, as well a structure of the C-terminal half of LRRK1.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature structural & molecular biology","journal_abbreviation":"Nat Struct Mol Biol","issue":"12","preprint":false}],"dataset_size":"643.9 GB","experiment_type":"EMDB","scale":"molecule","entry_doi":"10.6019/EMPIAR-10924"}}