{"EMPIAR-10877":{"imagesets":[{"segmentations":[],"name":"unaligned multiframe micrographs of Ste2 in the antagonist-bound state","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":15751,"frames_per_image":59,"frame_range_min":1,"frame_range_max":59,"voxel_type":"UNSIGNED BYTE","pixel_width":0.86,"pixel_height":0.86,"micrographs_file_pattern":"data/All_movies/FoilHole_18713372_Data_18711474_18711476_20201219_063202_fractions.tiff","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Contains unaligned movies. Please use binned_gain.mrc as gain reference with 180 degrees rotation and flip left to right in RELION 3.1.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Structure of the GPCR dimer Ste2 bound to an antagonist","principal_investigator":[{"author_orcid":"0000-0001-8028-8486","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","telephone":"07733323307","fax":null,"first_name":"Vaithish","last_name":"Velazhahan","email":"vaithish [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10877"}],"status":"REL","deposition_date":"2021-11-22","release_date":"2022-03-21","obsolete_date":null,"update_date":"2022-03-21","corresponding_author":{"author":{"author_orcid":"0000-0002-2008-9183","middle_name":"Gordon","organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","first_name":"Christopher","last_name":"Tate","country":"United Kingdom"}},"authors":[{"author":{"name":"Velazhahan V","author_orcid":"0000-0001-8028-8486"}},{"author":{"name":"Tate CG","author_orcid":"0000-0002-2008-9183"}}],"cross_references":["EMD-13880"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Velazhahan V","author_orcid":"0000-0001-8028-8486"},{"name":"Ma N","author_orcid":null},{"name":"Vaidehi N","author_orcid":"0000-0001-8100-8132"},{"name":"Tate CG","author_orcid":"0000-0002-2008-9183"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Activation mechanism of the class D fungal GPCR dimer Ste2","volume":null,"country":"","first_page":null,"last_page":null,"year":"2022","language":"English","doi":"10.1038/s41586-022-04498-3","pubmedid":"35296853","details":"The micrographs are raw movies of the GPCR dimer Ste2 bound to an antagonist","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":null,"preprint":false}],"dataset_size":"4.1 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["7qa8"],"entry_doi":"10.6019/EMPIAR-10877"}}