{"EMPIAR-10872":{"imagesets":[{"segmentations":[],"name":"Native-SCR-tetramer-frames","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3854,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.837,"pixel_height":0.837,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Oligomeric interactions maintain active-site structure in a non-cooperative enzyme family","principal_investigator":[{"author_orcid":"0000-0003-0034-5167","middle_name":"Francis","organization":"Department of Biological Sciences, Columbia University","street":"702A Sherman Fairchild Center, MC2434","town_or_city":"New York","state_or_province":"NY","post_or_zip":"10027","telephone":"16462705012","fax":null,"first_name":"John","last_name":"Hunt","email":"jfh21 [at] columbia.edu","country":"United States","entry":"EMPIAR-10872"}],"status":"REL","deposition_date":"2021-11-14","release_date":"2022-09-06","obsolete_date":null,"update_date":"2022-09-06","corresponding_author":{"author":{"author_orcid":"0000-0003-0034-5167","middle_name":"Francis","organization":"Department of Biological Sciences, Columbia University","street":"702A Sherman Fairchild Center, MC2434","town_or_city":"New York","state_or_province":"NY","post_or_zip":"10027","first_name":"John","last_name":"Hunt","country":"United States"}},"authors":[{"author":{"name":"Li YH","author_orcid":"0000-0002-9742-2829"}},{"author":{"name":"Zhang RZ","author_orcid":"0000-0001-6078-0174"}},{"author":{"name":"Chi W","author_orcid":"0000-0002-3081-3294"}},{"author":{"name":"Forouhar F","author_orcid":"0000-0002-5571-7397"}},{"author":{"name":"Clarke OB","author_orcid":"0000-0003-1876-196X"}},{"author":{"name":"Vorobiev S","author_orcid":"0000-0001-8537-3671"}},{"author":{"name":"Singh S","author_orcid":"0000-0003-0266-4241"}},{"author":{"name":"Montelione GT","author_orcid":"0000-0002-9440-3059"}},{"author":{"name":"Szyperski T","author_orcid":"0000-0003-0272-1373"}},{"author":{"name":"Xu Y","author_orcid":"0000-0002-7919-4762"}},{"author":{"name":"Hunt JF","author_orcid":"0000-0003-0034-5167"}}],"cross_references":["EMD-32211","EMD-32212","EMD-32213"],"biostudies_references":[],"idr_references":[],"empiar_references":[{"name":"EMPIAR-10872"}],"citation":[{"authors":[{"name":"Li Y","author_orcid":"0000-0002-9742-2829"},{"name":"Zhang R","author_orcid":"0000-0001-6078-0174"},{"name":"Wang C","author_orcid":"0000-0002-3081-3294"},{"name":"Forouhar F","author_orcid":"0000-0002-5571-7397"},{"name":"Clarke OB","author_orcid":"0000-0003-1876-196X"},{"name":"Vorobiev S","author_orcid":"0000-0001-8537-3671"},{"name":"Singh S","author_orcid":"0000-0003-0266-4241"},{"name":"Montelione GT","author_orcid":"0000-0002-9440-3059"},{"name":"Szyperski T","author_orcid":"0000-0003-0272-1373"},{"name":"Xu Y","author_orcid":"0000-0002-7919-4762"},{"name":"Hunt JF","author_orcid":"0000-0003-0034-5167"}],"editors":[{"name":" ","author_orcid":null}],"published":true,"j_or_nj_citation":true,"title":"Oligomeric interactions maintain active-site structure in a noncooperative enzyme family","volume":"41","country":"","first_page":null,"last_page":null,"year":"2022","language":"English","doi":"10.15252/embj.2021108368","pubmedid":"35801308","details":"Exposures of 2.5 s were dose-fractionated into 50 frames (50 ms/frame), with an exposure rate of 16 electrons/pixel/sec, resulting in a total exposure of 56.15 electrons/A2. The images were recorded using a K3 camera and imaging filter (Gatan Inc., USA) in counting mode at a nominal magnification of 105,000× (nominal pixel size of 0.844 #A/pixel, which was refined to 0.837 #A/pixel based on calibration of the final ST map against the crystal structure of the SCR/NADPH complex) with a defocus range from -1.34 to -2.17 μm.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"The EMBO journal","journal_abbreviation":"EMBO J","issue":"17","preprint":false}],"dataset_size":"902.0 GB","experiment_type":"EMDB","scale":"molecule","related_pdb_entries":["7vyq"],"entry_doi":"10.6019/EMPIAR-10872"}}