{"EMPIAR-10831":{"imagesets":[{"segmentations":[],"name":"Unaligned multiframe movies","directory":"data/Individual_1_MCx/Movies","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":12245,"frames_per_image":40,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.93,"pixel_height":0.93,"micrographs_file_pattern":"data/Individual_1_MCx/Movies/GridSquare_*/Data/*_fractions.tiff","picked_particles_file_pattern":"data/Individual_1_MCx/Start_end_coordinates/GridSquare_*/Data/*_manualpick.star","picked_particles_directory":"data/Individual_1_MCx/Start_end_coordinates","details":"The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.93 Å/px. The dose rate is 0.99 e/Å2/frame. Please use the gain.tiff file a gain reference without any rotation or flipping.","image_width":"5760","image_height":"4092"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Structure of pathological TDP-43 filaments from ALS with FTLD (Individual 1, motor cortex)","principal_investigator":[{"author_orcid":"0000-0002-8176-2618","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"CB2 0QH","telephone":null,"fax":null,"first_name":"Benjamin","last_name":"Falcon","email":"bfalcon [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10831"}],"status":"REL","deposition_date":"2021-10-09","release_date":"2022-01-21","obsolete_date":null,"update_date":"2022-01-21","corresponding_author":{"author":{"author_orcid":"0000-0002-8176-2618","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"CB2 0QH","first_name":"Benjamin","last_name":"Falcon","country":"United Kingdom"}},"authors":[{"author":{"name":"Arseni D","author_orcid":"0000-0001-7585-288X"}},{"author":{"name":"Hasegawa M","author_orcid":"0000-0001-7415-8159"}},{"author":{"name":"Murzin AG","author_orcid":null}},{"author":{"name":"Kametani F","author_orcid":"0000-0001-9125-7001"}},{"author":{"name":"Arai M","author_orcid":"0000-0003-3400-9815"}},{"author":{"name":"Yoshida M","author_orcid":null}},{"author":{"name":"Ryskeldi-Falcon B","author_orcid":"0000-0002-8176-2618"}}],"cross_references":["EMD-13710"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Arseni D","author_orcid":"0000-0001-7585-288X"},{"name":"Hasegawa M","author_orcid":"0000-0001-7415-8159"},{"name":"Murzin AG","author_orcid":null},{"name":"Kametani F","author_orcid":"0000-0001-9125-7001"},{"name":"Arai M","author_orcid":"0000-0003-3400-9815"},{"name":"Yoshida M","author_orcid":null},{"name":"Ryskeldi-Falcon B","author_orcid":"0000-0002-8176-2618"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structure of pathological TDP-43 filaments from ALS with FTLD","volume":"601","country":"","first_page":"139","last_page":"143","year":"2021","language":"English","doi":"10.1038/s41586-021-04199-3","pubmedid":"34880495","details":"The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.93 Å/px. The dose rate is 0.99 e/Å2/frame. Please use the gain.tiff file a gain reference without any rotation or flipping.\n\nStart_end_coordinates contains start-end coordinates of the manually picked filaments.\n\nData.star is a STAR file with the metadata of the final refined segments.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":"7891","preprint":false}],"dataset_size":"2.0 TB","experiment_type":"EMDB","scale":null,"entry_doi":"10.6019/EMPIAR-10831"}}