{"EMPIAR-10604":{"imagesets":[{"segmentations":[],"name":"Single particle cryo-EM dataset of Mus musculus mitochondrial complex I in the deactive state","directory":"data","category":"micrographs - multiframe","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":1768,"frames_per_image":30,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.35,"pixel_height":1.35,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Micrographs were imaged using a Gatan K2 summit camera in counting mode and GIF Quantum energy filter (20 eV slit width) on an FEI 300 keV Titan Krios microscope with a 100 μm objective aperture. 15 s exposures captured in 30 frames and a total dose of 50 electrons Å-2","image_width":"3838","image_height":"3710"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Single particle cryo-EM dataset of Mus musculus mitochondrial complex I in the deactive state","principal_investigator":[{"author_orcid":"0000-0001-8667-6797","middle_name":null,"organization":"MRC Mitochondrial Biology Unit, University of Cambridge","street":"Hills road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"Cb2 0xy","telephone":null,"fax":null,"first_name":"Judy","last_name":"Hirst","email":"jh [at] mrc-mbu.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10604"}],"status":"REL","deposition_date":"2020-12-07","release_date":"2021-02-12","obsolete_date":null,"update_date":"2021-02-12","corresponding_author":{"author":{"author_orcid":"0000-0001-6890-6050","middle_name":"Ruth","organization":"MRC Mitochondrial Biology Unit, University of Cambridge","street":"Hills road","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"Cb2 0xy","first_name":"Hannah","last_name":"Bridges","country":"United Kingdom"}},"authors":[{"author":{"name":"Yin Z","author_orcid":"0000-0002-3846-0147"}},{"author":{"name":"Bridges HR","author_orcid":"0000-0001-6890-6050"}},{"author":{"name":"Grba D","author_orcid":"0000-0003-2915-951X"}},{"author":{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}},{"author":{"name":"Blaza JN","author_orcid":"0000-0001-5420-2116"}},{"author":{"name":"Agip ANA","author_orcid":null}}],"cross_references":["EMD-11810","EMD-4356"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Yin Z","author_orcid":"0000-0002-3846-0147"},{"name":"Burger N","author_orcid":null},{"name":"Kula-Alwar D","author_orcid":null},{"name":"Aksentijević D","author_orcid":"0000-0002-8480-6727"},{"name":"Bridges HR","author_orcid":"0000-0001-6890-6050"},{"name":"Prag H","author_orcid":"0000-0002-4753-8567"},{"name":"Grba D","author_orcid":"0000-0003-2915-951X"},{"name":"Viscomi C","author_orcid":"0000-0001-6050-0566"},{"name":"James AJ","author_orcid":"0000-0002-0515-9649"},{"name":"Mottahedin A","author_orcid":"0000-0002-3677-2198"},{"name":"Kreig T","author_orcid":"0000-0002-5192-580X"},{"name":"Murphy MP","author_orcid":"0000-0003-1115-9618"},{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis for a complex I mutation that blocks pathological ROS production","volume":"12","country":"United States","first_page":null,"last_page":null,"year":"2021","language":"English","doi":"10.1038/s41467-021-20942-w","pubmedid":"33514727","details":"1768 multi-frame micrographs composed of 30 frames each in MRC format","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false},{"authors":[{"name":"Agip AA","author_orcid":null},{"name":"Blaza JN","author_orcid":"0000-0001-5420-2116"},{"name":"Bridges HR","author_orcid":"0000-0001-6890-6050"},{"name":"Viscomi C","author_orcid":"0000-0001-6050-0566"},{"name":"Rawson S","author_orcid":"0000-0002-2973-2630"},{"name":"Muench SP","author_orcid":"0000-0001-6869-4414"},{"name":"Hirst J","author_orcid":"0000-0001-8667-6797"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states","volume":"25","country":"","first_page":"548","last_page":"556","year":"2018","language":"English","doi":"10.1038/s41594-018-0073-1","pubmedid":"29915388","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature structural & molecular biology","journal_abbreviation":"Nat Struct Mol Biol","issue":"7","preprint":false}],"dataset_size":"2.7 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["7ak5","6g72"],"entry_doi":"10.6019/EMPIAR-10604"}}