{"EMPIAR-10596":{"imagesets":[{"segmentations":[],"name":"Unaligned multi frame micographs of CARD8-DPP9-VbP-noTILT","directory":"data/CARD_DPP9_VbP_Raw_Movies_noTILT","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1811,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.82,"pixel_height":0.82,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"For CARD8-DPP9-VbP 1,811 movies were collected at varying defocus levels ranging between −1.1 to −3.4 μm. One shot was recorded for each of the four holes per stage movement through image shift. All movies were exposed with a total dose of 67.06 e-/Å2 for 1.5 s fractionated over 50 frames. \"references\" folder contains the references.","image_width":null,"image_height":null},{"segmentations":[],"name":"Unaligned multi frame micographs of CARD8-DPP9-VbP-TILT","directory":"data/CARD_DPP9_VbP_Raw_Movies_TILT","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":6642,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.82,"pixel_height":0.82,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"For CARD8-DPP9-VbP tilt data, 6,642 movies at a stage tilt of 37° were collected at varying defocus levels ranging between −1.1 to −3.4 μm. One shot was recorded for each of the four holes per stage movement through image shift. All movies were exposed with a total dose of 67.06 e-/Å2 for 1.5 s fractionated over 50 frames. \"references\" folder contains the references.","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Human DPP9-CARD8 complex-VbP","principal_investigator":[{"author_orcid":"0000-0002-7281-8579","middle_name":null,"organization":"Harvard Medical School","street":null,"town_or_city":"Boston","state_or_province":"MA","post_or_zip":"02115","telephone":null,"fax":null,"first_name":"Hao","last_name":"Wu","email":"wu [at] crystal.harvard.edu","country":"United States","entry":"EMPIAR-10596"}],"status":"REL","deposition_date":"2020-12-13","release_date":"2021-05-25","obsolete_date":null,"update_date":"2022-02-15","corresponding_author":{"author":{"author_orcid":"0000-0002-7281-8579","middle_name":null,"organization":"HARVARD MEDICAL SCHOOL","street":null,"town_or_city":"Boston","state_or_province":"MA","post_or_zip":"02115","first_name":"Hao","last_name":"Wu","country":"United States"}},"authors":[{"author":{"name":"Sharif H","author_orcid":"0000-0003-1308-3442"}},{"author":{"name":"Hollingsworth LR","author_orcid":"0000-0002-4130-3580"}},{"author":{"name":"Griswold AR","author_orcid":null}},{"author":{"name":"Hsiao JC","author_orcid":null}},{"author":{"name":"Wang Q","author_orcid":null}},{"author":{"name":"Bachovchin DA","author_orcid":null}},{"author":{"name":"Wu H","author_orcid":"0000-0002-7281-8579"}}],"cross_references":["EMD-22402"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Sharif H","author_orcid":"0000-0003-1308-3442"},{"name":"Hollingsworth LR","author_orcid":"0000-0002-4130-3580"},{"name":"Griswold AR","author_orcid":null},{"name":"Hsiao JC","author_orcid":null},{"name":"Wang Q","author_orcid":null},{"name":"Bachovchin DA","author_orcid":null},{"name":"Wu H","author_orcid":"0000-0002-7281-8579"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment","volume":"54","country":"","first_page":"1392","last_page":"1404.e10","year":"2021","language":"English","doi":"10.1016/j.immuni.2021.04.024","pubmedid":"34019797","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Immunity","journal_abbreviation":"Immunity","issue":"7","preprint":false}],"dataset_size":"2.1 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["7jn7"],"entry_doi":"10.6019/EMPIAR-10596"}}