{"EMPIAR-10595":{"imagesets":[{"segmentations":[],"name":"Unaligned multi frame micographs of NLRP1-DPP9-VbP-noTILT","directory":"data/NLRP1_DPP9_VbP_Raw_Movies_noTILT","category":"micrographs - focal pairs - unprocessed","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3553,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.825,"pixel_height":0.825,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"The defocus range between −0.8 to −2.2 μm and to record two shots for each of the four holes per stage movement through image shift. All movies were exposed with a total dose of 52.0 e-/Å2 for 2.0 s fractionated over 50 frames.","image_width":null,"image_height":null},{"segmentations":[],"name":"Unaligned multi frame micographs of NLRP1-DPP9-VbP-TILT","directory":"data/NLRP1_DPP9_VbP_Raw_Movies_TILT","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1954,"frames_per_image":43,"frame_range_min":null,"frame_range_max":null,"voxel_type":"BIT","pixel_width":0.825,"pixel_height":0.825,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"An ideal tilt angle of 37° was calculated from this processed dataset using cryoEF. The defocus range between −1.5 to −3.0 μm with two shots recorded for each hole per stage movement through image shift. All movies were\nexposed with a total dose of 65.0 e-/Å2 for 2.4 s fractionated over 43 frames","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Human NLRP1-DPP9-VbP complex","principal_investigator":[{"author_orcid":"0000-0002-7281-8579","middle_name":null,"organization":"HARVARD MEDICAL SCHOOL","street":null,"town_or_city":"Boston","state_or_province":"MA","post_or_zip":"02115","telephone":null,"fax":null,"first_name":"Hao","last_name":"Wu","email":"wu [at] crystal.harvard.edu","country":"United States","entry":"EMPIAR-10595"}],"status":"REL","deposition_date":"2020-12-15","release_date":"2021-04-14","obsolete_date":null,"update_date":"2021-04-14","corresponding_author":{"author":{"author_orcid":"0000-0002-7281-8579","middle_name":null,"organization":"HARVARD MEDICAL SCHOOL","street":null,"town_or_city":"Boston","state_or_province":"MA","post_or_zip":"02115","first_name":"Hao","last_name":"Wu","country":"United States"}},"authors":[{"author":{"name":"Hollingsworth LR","author_orcid":"0000-0002-4130-3580"}},{"author":{"name":"Sharif H","author_orcid":"0000-0003-1308-3442"}},{"author":{"name":"Wu H","author_orcid":"0000-0002-7281-8579"}}],"cross_references":["EMD-22075"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Hollingsworth LR","author_orcid":"0000-0002-4130-3580"},{"name":"Sharif H","author_orcid":"0000-0003-1308-3442"},{"name":"Griswold AR","author_orcid":"0000-0003-2957-2355"},{"name":"Fontana P","author_orcid":null},{"name":"Mintseris J","author_orcid":null},{"name":"Dagbay KB","author_orcid":"0000-0001-7002-7207"},{"name":"Paulo JA","author_orcid":"0000-0002-4291-413X"},{"name":"Gygi SP","author_orcid":"0000-0001-7626-0034"},{"name":"Bachovchin DA","author_orcid":"0000-0001-8210-1662"},{"name":"Wu H","author_orcid":"0000-0002-7281-8579"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation","volume":null,"country":"United States","first_page":null,"last_page":null,"year":"2021","language":"English","doi":"10.1038/s41586-021-03350-4","pubmedid":"33731932","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":null,"preprint":false}],"dataset_size":"1.2 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["6x6c"],"entry_doi":"10.6019/EMPIAR-10595"}}