{"EMPIAR-10590":{"imagesets":[{"segmentations":[],"name":"Motion-corrected micrographs of the endogenous human BAF complex on thin-layer carbon grids","directory":"data/micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":4865,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.5,"pixel_height":1.5,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Motion-corrected averages of movies collected at an accumulated dose of 66.7 e-/A^2 across 50 frames over a 15 s exposure, recorded on Talos Arctica (FEI) with a K2 Summit direct detector (Gatan) in super-resolution counting mode. Motion correction was performed using MotionCor2 with dose weighting, 2x binning, and 5x5 patches.","image_width":"3710","image_height":"3838"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Single-particle Cryo-EM of the endogenous human BAF complex alone","principal_investigator":[{"author_orcid":"0000-0002-4058-5985","middle_name":null,"organization":"Department of Pediatric Oncology, Dana-Faber Cancer Institute","street":null,"town_or_city":"Boston","state_or_province":"Massachusetts","post_or_zip":"02215","telephone":null,"fax":null,"first_name":"Cigall","last_name":"Kadoch","email":"Cigall_Kadoch [at] dfci.harvard.edu","country":"United States","entry":"EMPIAR-10590"}],"status":"REL","deposition_date":"2020-10-15","release_date":"2020-12-22","obsolete_date":null,"update_date":"2020-12-22","corresponding_author":{"author":{"author_orcid":"0000-0003-2606-2835","middle_name":null,"organization":"Laboratory of Molecular Electron Microscopy, The Rockefeller University","street":null,"town_or_city":"New York","state_or_province":"New York","post_or_zip":"10065","first_name":"Thomas","last_name":"Walz","country":"United States"}},"authors":[{"author":{"name":"Suzuki H","author_orcid":"0000-0001-5371-6385"}},{"author":{"name":"Mashtalir N","author_orcid":"0000-0002-6624-4839"}},{"author":{"name":"Kadoch C","author_orcid":"0000-0002-4058-5985"}},{"author":{"name":"Walz T","author_orcid":"0000-0003-2606-2835"}}],"cross_references":["EMD-22476"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Mashtalir N","author_orcid":"0000-0002-6624-4839"},{"name":"Suzuki H","author_orcid":"0000-0001-5371-6385"},{"name":"Farrell DP","author_orcid":null},{"name":"Sankar A","author_orcid":null},{"name":"Luo J","author_orcid":null},{"name":"Filipovski M","author_orcid":null},{"name":"D'Avino AR","author_orcid":null},{"name":"St Pierre R","author_orcid":null},{"name":"Valencia AM","author_orcid":null},{"name":"Onikubo T","author_orcid":null},{"name":"Roeder RG","author_orcid":null},{"name":"Han Y","author_orcid":null},{"name":"He Y","author_orcid":null},{"name":"Ranish JA","author_orcid":null},{"name":"DiMaio F","author_orcid":null},{"name":"Walz T","author_orcid":"0000-0003-2606-2835"},{"name":"Kadoch C","author_orcid":"0000-0002-4058-5985"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms","volume":"183","country":"","first_page":"802","last_page":"817","year":"2020","language":"English","doi":"10.1016/j.cell.2020.09.051","pubmedid":"33053319","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Cell","journal_abbreviation":"Cell","issue":"3","preprint":false}],"dataset_size":"258.1 GB","experiment_type":"EMDB","scale":null,"entry_doi":"10.6019/EMPIAR-10590"}}