{"EMPIAR-10561":{"imagesets":[{"segmentations":[],"name":"Unaligned movies of human CAK-ICEC0942, dataset 1","directory":"data/movies/dataset1_20Jun27","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2466,"frames_per_image":70,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.343,"pixel_height":0.343,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned super-resolution electron micrograph movies. 70 frames per movie with an accumulated exposure of 69 electrons per Angstrom squared. Movies are not gain corrected (gain reference is provided). Movies with numbers below 279 and those with numbers above that should be treated as separate optics groups (in addition to the groups for acquisition spots 1-9).","image_width":"11520","image_height":"8184"},{"segmentations":[],"name":"Unaligned movies of human CAK-ICEC0942, dataset 3","directory":"data/movies/dataset3_20Jul28","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":1179,"frames_per_image":70,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.343,"pixel_height":0.343,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned super-resolution electron micrograph movies without gain correction (gain reference is provided). 70 frames per movie with an accumulated exposure of 69 electrons per Angstrom squared. Acquisition spots 1-9 should be treated as separate optics groups.","image_width":"11520","image_height":"8184"},{"segmentations":[],"name":"Unaligned movies of human CAK-ICEC0942, dataset 2","directory":"data/movies/dataset2_20Jul27","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3340,"frames_per_image":69,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":0.343,"pixel_height":0.343,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned super-resolution electron micrograph movies without gain correction (gain reference is provided). 69 frames per movie with an accumulated exposure of 69 electrons per Angstrom squared. Acquisition spots 1-9 should be treated as separate optics groups.","image_width":"11520","image_height":"8184"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo-EM structure of the human CDK-activating kinase bound to the clinical inhibitor ICEC0942","principal_investigator":[{"author_orcid":"0000-0001-9379-7159","middle_name":"J","organization":"The Institute of Cancer Research","street":null,"town_or_city":"London","state_or_province":null,"post_or_zip":"SW3 6JB","telephone":null,"fax":null,"first_name":"Basil","last_name":"Greber","email":"basilgreber [at] gmx.net","country":"United Kingdom","entry":"EMPIAR-10561"},{"author_orcid":"0000-0001-9816-3681","middle_name":null,"organization":"QB3, University of California, Berkeley and HHMI","street":null,"town_or_city":"Berkeley","state_or_province":"California","post_or_zip":"94720","telephone":null,"fax":null,"first_name":"Eva","last_name":"Nogales","email":"enogales [at] lbl.gov","country":"United States","entry":"EMPIAR-10561"}],"status":"REL","deposition_date":"2020-10-30","release_date":"2021-01-29","obsolete_date":null,"update_date":"2021-06-04","corresponding_author":{"author":{"author_orcid":"0000-0001-9379-7159","middle_name":"J","organization":"The Institute of Cancer Research","street":null,"town_or_city":"London","state_or_province":null,"post_or_zip":"SW3 6JB","first_name":"Basil","last_name":"Greber","country":"United Kingdom"}},"authors":[{"author":{"name":"Greber BJ","author_orcid":"0000-0001-9379-7159"}},{"author":{"name":"Remis J","author_orcid":null}},{"author":{"name":"Ali S","author_orcid":"0000-0002-1320-0816"}},{"author":{"name":"Nogales E","author_orcid":"0000-0001-9816-3681"}}],"cross_references":["EMD-12042","EMD-11823"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Greber BJ","author_orcid":"0000-0001-9379-7159"},{"name":"Remis J","author_orcid":null},{"name":"Ali S","author_orcid":"0000-0002-1320-0816"},{"name":"Nogales E","author_orcid":"0000-0001-9816-3681"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"2.5 Å-resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942","volume":"120","country":"","first_page":"677","last_page":"686","year":"2021","language":"English","doi":"10.1016/j.bpj.2020.12.030","pubmedid":"33476598","details":"The deposited files are unaligned movies in TIFF format.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Biophysical journal","journal_abbreviation":"Biophys J","issue":"4","preprint":false}],"dataset_size":"3.8 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["7b5o"],"entry_doi":"10.6019/EMPIAR-10561"}}