{"EMPIAR-10490":{"imagesets":[{"segmentations":[],"name":"MOI0.5-24h-Dual axis tilt series","directory":"data/Tomography/Calu3_MOI0.5_24h_H2/raw_tilt","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":202,"frames_per_image":121,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 0.5, 24h post infection;\nDual axis tilt series, both axes as individual *.st MRC files","image_width":"2024","image_height":"2024"},{"segmentations":[],"name":"MOI5-12h-Dual axis tilt series","directory":"data/Tomography/Calu3_MOI5_12h_E3/raw_tilt","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":178,"frames_per_image":121,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 12h post infection;\nDual axis tilt series, both axes as individual *.st MRC files","image_width":"2024","image_height":"2024"},{"segmentations":[],"name":"MOI5-24h-Dual axis tilt series","directory":"data/Tomography/Calu3_MOI5_24h_C2/raw_tilt","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":152,"frames_per_image":121,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 24h post infection;\nDual axis tilt series, both axes as individual *.st MRC files","image_width":"2024","image_height":"2024"},{"segmentations":[],"name":"MOI5-6h-Dual axis tilt series","directory":"data/Tomography/Calu_MOI5_6h_K2/raw_tilt","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":14,"frames_per_image":121,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 6h post infection;\nDual axis tilt series, both axes as individual *.st MRC files","image_width":"2024","image_height":"2024"},{"segmentations":[],"name":"MOI0.5-24h-Reconstructed tomograms","directory":"data/Tomography/Calu3_MOI0.5_24h_H2/tomos","category":"reconstructed volumes","header_format":"XML","data_format":"BIG DATA VIEWER HDF5","num_images_or_tilt_series":97,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 0.5, 24h post infection;\nReconstructed volume from dual axis tilt series, BDV HDF5 format, positioned according to physical location on specimen. Corresponding map files for targeting in adjacent \"maps\" directory.","image_width":null,"image_height":null},{"segmentations":[],"name":"MOI5-12h-Reconstructed tomograms","directory":"data/Tomography/Calu3_MOI5_12h_E3/tomos","category":"reconstructed volumes","header_format":"XML","data_format":"BIG DATA VIEWER HDF5","num_images_or_tilt_series":85,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 12h post infection;\nReconstructed volume from dual axis tilt series, BDV HDF5 format, positioned according to physical location on specimen. Corresponding map files for targeting in adjacent \"maps\" directory.","image_width":null,"image_height":null},{"segmentations":[],"name":"MOI5-24h-Reconstructed tomograms","directory":"data/Tomography/Calu3_MOI5_24h_C2/tomos","category":"reconstructed volumes","header_format":"XML","data_format":"BIG DATA VIEWER HDF5","num_images_or_tilt_series":56,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 24h post infection;\nReconstructed volume from dual axis tilt series, BDV HDF5 format, positioned according to physical location on specimen. Corresponding map files for targeting in adjacent \"maps\" directory.","image_width":null,"image_height":null},{"segmentations":[],"name":"MOI5-6h-Reconstructed tomograms","directory":"data/Tomography/Calu_MOI5_6h_K2/tomos","category":"reconstructed volumes","header_format":"XML","data_format":"BIG DATA VIEWER HDF5","num_images_or_tilt_series":7,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: MOI = 5, 6h post infection;\nReconstructed volume from dual axis tilt series, BDV HDF5 format, positioned according to physical location on specimen. Corresponding map files for targeting in adjacent \"maps\" directory.","image_width":null,"image_height":null},{"segmentations":[],"name":"S4 Area 2 FIB-SEM Volume 8nm isotropic","directory":"data/FIB-SEM/S4_area2","category":"micrographs - single frame","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4824,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":80.0,"pixel_height":80.0,"micrographs_file_pattern":"data/FIB-SEM/S4_area2/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"S4 Area 2 FIB-SEM Volume 8nm isotropic voxel size, aligned","image_width":"3864","image_height":"3144"},{"segmentations":[],"name":"S4 Area 3 FIB-SEM Volume 8nm isotropic","directory":"data/FIB-SEM/S4_area3","category":"micrographs - single frame","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":4413,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":80.0,"pixel_height":80.0,"micrographs_file_pattern":"data/FIB-SEM/S4_area3/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"S4 Area 3 FIB-SEM Volume 8nm isotropic voxel size, aligned","image_width":"5632","image_height":"3648"},{"segmentations":[],"name":"S4 Cell 1 FIB-SEM Volume 5nm isotropic","directory":"data/FIB-SEM/S4_cell1_5nm","category":"micrographs - single frame","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":11199,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":50.0,"pixel_height":50.0,"micrographs_file_pattern":"data/FIB-SEM/S4_cell1_5nm/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"S4 Cell 1 FIB-SEM Volume 5nm isotropic voxel size, aligned","image_width":"7512","image_height":"3864"},{"segmentations":[],"name":"S5 Mock Cell 1 FIB-SEM Volume 8nm isotropic","directory":"data/FIB-SEM/S5_mock_cell1_2","category":"micrographs - single frame","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":2574,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":80.0,"pixel_height":80.0,"micrographs_file_pattern":"data/FIB-SEM/S5_mock_cell1_2/*.tif","picked_particles_file_pattern":"","picked_particles_directory":"","details":"S5 Mock/Control Cell 1 FIB-SEM Volume 8nm isotropic voxel size, aligned","image_width":"6624","image_height":"4236"},{"segmentations":[],"name":"Mock cells - Dual axis tilt series","directory":"data/Tomography/Mock/raw_tilts","category":"tilt series","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":26,"frames_per_image":121,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: Mock;\nDual axis tilt series, both axes as individual *.st MRC files","image_width":"2024","image_height":"2024"},{"segmentations":[],"name":"Mock cells-Reconstructed tomograms","directory":"data/Tomography/Mock/tomos","category":"reconstructed volumes","header_format":"XML","data_format":"BIG DATA VIEWER HDF5","num_images_or_tilt_series":13,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED BYTE","pixel_width":15.578,"pixel_height":15.578,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Condition: Mock;\nReconstructed volume from dual axis tilt series, BDV HDF5 format, positioned according to physical location on specimen. Corresponding map files for targeting in adjacent \"maps\" directory.","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Integrative imaging reveals SARS-CoV-2 induced reshaping of subcellular morphology","principal_investigator":[{"author_orcid":"0000-0001-5601-9307","middle_name":null,"organization":"Department of Infectious Diseases, Molecular Virology, Heidelberg University","street":null,"town_or_city":"Heidelberg","state_or_province":null,"post_or_zip":"69120","telephone":null,"fax":null,"first_name":"Ralf","last_name":"Bartenschlager","email":"Ralf.Bartenschlager [at] med.uni-heidelberg.de","country":"Germany","entry":"EMPIAR-10490"},{"author_orcid":null,"middle_name":null,"organization":"Cell Biology and Biophysics Unit, EMBL","street":null,"town_or_city":"Heidelberg","state_or_province":null,"post_or_zip":"69117","telephone":null,"fax":null,"first_name":"Yannick","last_name":"Schwab","email":"schwab [at] embl.de","country":"Germany","entry":"EMPIAR-10490"}],"status":"REL","deposition_date":"2020-06-24","release_date":"2020-12-11","obsolete_date":null,"update_date":"2021-10-25","corresponding_author":{"author":{"author_orcid":"0000-0001-5601-9307","middle_name":null,"organization":"Department of Infectious Diseases, Molecular Virology, Heidelberg University","street":null,"town_or_city":"Heidelberg","state_or_province":null,"post_or_zip":"69120","first_name":"Ralf","last_name":"Bartenschlager","country":"Germany"}},"authors":[{"author":{"name":"Cortese M","author_orcid":null}},{"author":{"name":"Lee JY","author_orcid":null}},{"author":{"name":"Cerikan B","author_orcid":null}},{"author":{"name":"Neufeldt CJ","author_orcid":null}},{"author":{"name":"Oorschot VMJ","author_orcid":null}},{"author":{"name":"Köhrer S","author_orcid":null}},{"author":{"name":"Hennies J","author_orcid":null}},{"author":{"name":"Schieber NL","author_orcid":null}},{"author":{"name":"Ronchi P","author_orcid":null}},{"author":{"name":"Mizzon G","author_orcid":null}},{"author":{"name":"Romero-Brey I","author_orcid":null}},{"author":{"name":"Santarella-Mellwig R","author_orcid":null}},{"author":{"name":"Schorb M","author_orcid":null}},{"author":{"name":"Boermel M","author_orcid":null}},{"author":{"name":"Mocaer K","author_orcid":null}},{"author":{"name":"Beckwith MS","author_orcid":null}},{"author":{"name":"Templin RM","author_orcid":null}},{"author":{"name":"Gross V","author_orcid":null}},{"author":{"name":"Pape C","author_orcid":null}},{"author":{"name":"Tischer C","author_orcid":null}},{"author":{"name":"Frankish J","author_orcid":null}},{"author":{"name":"Horvat NK","author_orcid":null}},{"author":{"name":"Laketa V","author_orcid":null}},{"author":{"name":"Stanifer M","author_orcid":null}},{"author":{"name":"Boulant S","author_orcid":null}},{"author":{"name":"Ruggieri A","author_orcid":null}},{"author":{"name":"Chatel-Chaix L","author_orcid":null}},{"author":{"name":"Schwab Y","author_orcid":null}},{"author":{"name":"Bartenschlager R","author_orcid":null}}],"cross_references":["EMD-12940"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Cortese M","author_orcid":null},{"name":"Lee JY","author_orcid":null},{"name":"Cerikan B","author_orcid":null},{"name":"Neufeldt CJ","author_orcid":null},{"name":"Oorschot VMJ","author_orcid":null},{"name":"Köhrer S","author_orcid":null},{"name":"Hennies J","author_orcid":null},{"name":"Schieber NL","author_orcid":null},{"name":"Ronchi P","author_orcid":null},{"name":"Mizzon G","author_orcid":null},{"name":"Romero-Brey I","author_orcid":null},{"name":"Santarella-Mellwig R","author_orcid":null},{"name":"Schorb M","author_orcid":null},{"name":"Boermel M","author_orcid":null},{"name":"Mocaer K","author_orcid":null},{"name":"Beckwith MS","author_orcid":null},{"name":"Templin RM","author_orcid":null},{"name":"Gross V","author_orcid":null},{"name":"Pape C","author_orcid":null},{"name":"Tischer C","author_orcid":null},{"name":"Frankish J","author_orcid":null},{"name":"Horvat NK","author_orcid":null},{"name":"Laketa V","author_orcid":null},{"name":"Stanifer M","author_orcid":null},{"name":"Boulant S","author_orcid":null},{"name":"Ruggieri A","author_orcid":null},{"name":"Chatel-Chaix L","author_orcid":null},{"name":"Schwab Y","author_orcid":null},{"name":"Bartenschlager R","author_orcid":null}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies","volume":null,"country":"","first_page":null,"last_page":null,"year":"2020","language":"English","doi":"10.1016/j.chom.2020.11.003","pubmedid":"33245857","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Cell host & microbe","journal_abbreviation":"Cell Host Microbe","issue":null,"preprint":false}],"dataset_size":"1.1 TB","experiment_type":"IHM","scale":null,"entry_doi":"10.6019/EMPIAR-10490"}}