{"EMPIAR-10473":{"imagesets":[{"segmentations":[],"name":"Unaligned micrograph frames from 110 internal SEMC/NYSBC test datasets","directory":"data/frames","category":"micrographs - single frame","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":1000000,"frames_per_image":50,"frame_range_min":null,"frame_range_max":null,"voxel_type":"UNSIGNED 16 BIT INTEGER","pixel_width":null,"pixel_height":null,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Here are micrograph frames for 110 internal SEMC/NYSBC datasets that we used to generate and analyze numerous different denoising models when writing the Topaz-Denoise software and manuscript. Many of these datasets were used in the pre-trained denoising models included in Topaz. Some frames are in mrcs format, some are in tiff format, and some are zipped with bzip2.\n\nIn this EMPIAR entry, you will find an Excel (.xlsx) with sample information, pixelsize, microscope information, and total dose for each dataset.","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Micrograph frames from 110 internal SEMC/NYSBC test datasets used for Topaz-Denoise model generation & analysis","principal_investigator":[{"author_orcid":null,"middle_name":null,"organization":"Massachusetts Institute of Technology","street":"77 Massachusetts Avenue","town_or_city":"Cambridge","state_or_province":"Massachusetts","post_or_zip":"02139","telephone":null,"fax":null,"first_name":"Bonnie","last_name":"Berger","email":"bab [at] mit.edu","country":"United States","entry":"EMPIAR-10473"},{"author_orcid":"0000-0001-8634-2279","middle_name":null,"organization":"New York Structural Biology Center","street":"89 Convent Avenue","town_or_city":"New York","state_or_province":"NY","post_or_zip":"10027","telephone":null,"fax":null,"first_name":"Alex","last_name":"Noble","email":"anoble [at] nysbc.org","country":"United States","entry":"EMPIAR-10473"}],"status":"REL","deposition_date":"2019-06-18","release_date":"2020-11-27","obsolete_date":null,"update_date":"2021-09-07","corresponding_author":{"author":{"author_orcid":null,"middle_name":null,"organization":"Massachusetts Institute of Technology","street":"77 Massachusetts Avenue","town_or_city":"Cambridge","state_or_province":"Massachusetts","post_or_zip":"02139","first_name":"Bonnie","last_name":"Berger","country":"United States"}},"authors":[{"author":{"name":"Bepler T","author_orcid":"0000-0001-5595-9954"}},{"author":{"name":"Kelley K","author_orcid":null}},{"author":{"name":"Noble AJ","author_orcid":"0000-0001-8634-2279"}},{"author":{"name":"Berger B","author_orcid":"0000-0002-2724-7228"}}],"cross_references":["EMD-22056","EMD-22052","EMD-22059","EMD-22053","EMD-22057","EMD-22058","EMD-22060"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Bepler T","author_orcid":"0000-0001-5595-9954"},{"name":"Kelley K","author_orcid":null},{"name":"Noble AJ","author_orcid":"0000-0001-8634-2279"},{"name":"Berger B","author_orcid":"0000-0002-2724-7228"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Topaz-Denoise: general deep denoising models for cryoEM and cryoET","volume":"11","country":"United States","first_page":null,"last_page":null,"year":"2020","language":"English","doi":"10.1038/s41467-020-18952-1","pubmedid":"33060581","details":"Includes raw frames, aligned micrographs using MotionCor2 with 5x5 patches, and naively summed micrographs.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature communications","journal_abbreviation":"Nat Commun","issue":"1","preprint":false}],"dataset_size":"33.9 TB","experiment_type":"EMDB","scale":null,"entry_doi":"10.6019/EMPIAR-10473"}}