{"EMPIAR-10383":{"imagesets":[{"segmentations":[],"name":"Unaligned movies of human LRRC8D isoform","directory":"data","category":"micrographs - multiframe","header_format":"TIFF","data_format":"TIFF","num_images_or_tilt_series":3399,"frames_per_image":40,"frame_range_min":1,"frame_range_max":40,"voxel_type":"UNSIGNED BYTE","pixel_width":1.49,"pixel_height":1.49,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Movies were collected on Talos Arctica at 0.745 A / super-resolution pixel (that is, 1.49 A / physical pixel). Gain references must be rotated and flipped. In MotionCor2, this is \"-RotGain 1 -FlipGain 2\". Seven datasets were combined to yield the structure.\nDose rate (shown on SerialEM) of Datasets 0 and 1 are 1.245 e/A2/frame","image_width":"7420","image_height":"7676"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"CryoEM structure of human LRRC8D","principal_investigator":[{"author_orcid":"0000-0003-1813-7008","middle_name":null,"organization":"Department of Biological Sciences, School of Science, The University of Tokyo","street":"7-3-1 Hongo","town_or_city":"Bunkyo-ku","state_or_province":"Tokyo","post_or_zip":"113-0033","telephone":"+81 3 5841 4392","fax":"+81 3 5841 8057","first_name":"Osamu","last_name":"Nureki","email":"nureki [at] bs.s.u-tokyo.ac.jp","country":"Japan","entry":"EMPIAR-10383"}],"status":"REL","deposition_date":"2020-03-05","release_date":"2021-11-09","obsolete_date":null,"update_date":"2023-05-02","corresponding_author":{"author":{"author_orcid":"0000-0003-1813-7008","middle_name":null,"organization":"Department of Biological Sciences, School of Science, The University of Tokyo","street":"7-3-1 Hongo","town_or_city":"Bunkyo-ku","state_or_province":"Tokyo","post_or_zip":"113-0033","first_name":"Osamu","last_name":"Nureki","country":"Japan"}},"authors":[{"author":{"name":"Nakamura R","author_orcid":null}},{"author":{"name":"Kasuya G","author_orcid":"0000-0003-1756-5764"}},{"author":{"name":"Yokoyama T","author_orcid":null}},{"author":{"name":"Shirouzu M","author_orcid":"0000-0002-7997-2149"}},{"author":{"name":"Ishitani R","author_orcid":"0000-0002-4136-5685"}},{"author":{"name":"Nureki O","author_orcid":"0000-0003-1813-7008"}}],"cross_references":["EMD-30029"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Nakamura R","author_orcid":null},{"name":"Numata T","author_orcid":"0000-0002-5719-4884"},{"name":"Kasuya G","author_orcid":"0000-0003-1756-5764"},{"name":"Yokoyama T","author_orcid":null},{"name":"Nishizawa T","author_orcid":"0000-0001-7463-8398"},{"name":"Kusakizako T","author_orcid":"0000-0002-6186-6647"},{"name":"Kato T","author_orcid":null},{"name":"Hagino T","author_orcid":null},{"name":"Dohmae N","author_orcid":null},{"name":"Inoue M","author_orcid":null},{"name":"Watanabe K","author_orcid":"0000-0002-0348-1634"},{"name":"Ichijo H","author_orcid":"0000-0002-5005-6438"},{"name":"Kikkawa M","author_orcid":"0000-0001-7656-8194"},{"name":"Shirouzu M","author_orcid":"0000-0002-7997-2149"},{"name":"Jentsch TJ","author_orcid":"0000-0002-3509-2553"},{"name":"Ishitani R","author_orcid":null},{"name":"Okada Y","author_orcid":null},{"name":"Nureki O","author_orcid":"0000-0003-1813-7008"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation","volume":"3","country":"Japan","first_page":null,"last_page":null,"year":"2020","language":"English","doi":"10.1038/s42003-020-0951-z","pubmedid":"32415200","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Communications biology","journal_abbreviation":"Commun Biol","issue":"1","preprint":false}],"dataset_size":"1.7 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["6m04"],"entry_doi":"10.6019/EMPIAR-10383"}}