{"EMPIAR-10374":{"imagesets":[{"segmentations":[],"name":"Unaligned super-resolution multi-frame micrographs of MZ-29 inhibitor bound ABCG2-Fab.","directory":"data/Movies","category":"micrographs - multiframe","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":4094,"frames_per_image":50,"frame_range_min":1,"frame_range_max":50,"voxel_type":"4 BIT INTEGER","pixel_width":0.42,"pixel_height":0.42,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"Unaligned super-resolution (K2 camera) multi-frame micrographs of MZ-29 inhibitor bound ABCG2-Fab. One movie is made of 50 frames (10sec in total/0.2s per frame, frame dose is 2.0 e/A2).","image_width":"7676","image_height":"7420"},{"segmentations":[],"name":"Extracted particles and corresponding star file","directory":"data/Extracted_particles","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":587743,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":0.84,"pixel_height":0.84,"micrographs_file_pattern":"","picked_particles_file_pattern":"","picked_particles_directory":"","details":"All particles picked up with Gautomatch and extracted from all micrographs.","image_width":"384","image_height":"384"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"CryoEM reconstruction of human ABCG2 transporter with inhibitor MZ29 and 5D3-Fab","principal_investigator":[{"author_orcid":"0000-0002-8207-2889","middle_name":"P","organization":"ETH Zurich","street":"Otto-Stern-Weg 5","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8093","telephone":"+41-​44-633-3991","fax":null,"first_name":"Kaspar","last_name":"Locher","email":"locher [at] mol.biol.ethz.ch","country":"Switzerland","entry":"EMPIAR-10374"}],"status":"REL","deposition_date":"2020-02-12","release_date":"2020-07-15","obsolete_date":null,"update_date":"2020-07-15","corresponding_author":{"author":{"author_orcid":"0000-0002-8207-2889","middle_name":"P","organization":"ETH Zurich","street":"Otto-Stern-Weg 5","town_or_city":"Zurich","state_or_province":"ZH","post_or_zip":"8093","first_name":"Kaspar","last_name":"Locher","country":"Switzerland"}},"authors":[{"author":{"name":"Jackson SM","author_orcid":"0000-0002-8309-4713"}},{"author":{"name":"Manolaridis I","author_orcid":null}},{"author":{"name":"Kowal J","author_orcid":"0000-0003-4694-1896"}},{"author":{"name":"Zechner M","author_orcid":null}},{"author":{"name":"Taylor NMI","author_orcid":null}},{"author":{"name":"Bause M","author_orcid":null}},{"author":{"name":"Bauer S","author_orcid":null}},{"author":{"name":"Bartholomaeus R","author_orcid":null}},{"author":{"name":"Bernhardt G","author_orcid":null}},{"author":{"name":"Koenig B","author_orcid":null}},{"author":{"name":"Buschauer A","author_orcid":null}},{"author":{"name":"Stahlberg H","author_orcid":null}},{"author":{"name":"Altmann KH","author_orcid":null}},{"author":{"name":"Locher KP","author_orcid":"0000-0002-8207-2889"}}],"cross_references":["EMD-3953"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Jackson SM","author_orcid":"0000-0002-8309-4713"},{"name":"Manolaridis I","author_orcid":null},{"name":"Kowal J","author_orcid":"0000-0003-4694-1896"},{"name":"Zechner M","author_orcid":null},{"name":"Taylor NMI","author_orcid":"0000-0003-0761-4921"},{"name":"Bause M","author_orcid":null},{"name":"Bauer S","author_orcid":null},{"name":"Bartholomaeus R","author_orcid":null},{"name":"Bernhardt G","author_orcid":null},{"name":"Koenig B","author_orcid":"0000-0002-6131-4850"},{"name":"Buschauer A","author_orcid":null},{"name":"Stahlberg H","author_orcid":"0000-0002-1185-4592"},{"name":"Altmann KH","author_orcid":null},{"name":"Locher KP","author_orcid":"0000-0002-8207-2889"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structural basis of small-molecule inhibition of human multidrug transporter ABCG2","volume":"25","country":"","first_page":"333","last_page":"340","year":"2018","language":"English","doi":"10.1038/s41594-018-0049-1","pubmedid":"29610494","details":"Raw movies (mrc) without alignment with provided gain references, particles and final 3D refinement files with masks","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature structural & molecular biology","journal_abbreviation":"Nat. Struct. Mol. Biol.","issue":"4","preprint":false}],"dataset_size":"5.6 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["6eti"],"entry_doi":"10.6019/EMPIAR-10374"}}