{"EMPIAR-10230":{"imagesets":[{"segmentations":[],"name":"Dose-weighted micrographs of tau filaments from sporadic Alzheimer's disease brain (case 2)","directory":"data/AD_patient2_EMPIAR/DW_Micrographs","category":"micrographs - single frame","header_format":"MRC","data_format":"MRC","num_images_or_tilt_series":507,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.15,"pixel_height":1.15,"micrographs_file_pattern":"data/*/DW_Micrographs/*.mrc","picked_particles_file_pattern":"data/*/Coordinates/*.star","picked_particles_directory":"data/AD_patient2_EMPIAR/Coordinates","details":"Start- and end-points of filaments for PHFs and SFs written out as tube coordinate .star files with the following syntax (ignore comments after //):\n\ndata_ \n\nloop_ \n_rlnCoordinateX #1 \n_rlnCoordinateY #2 \n  110.000000  1080.000000   // Tube 1 starting coordinates x, y \n 1855.000000   585.000000   // Tube 1 end coordinates x, y \n  635.000000  1325.000000   // Tube 2 \n  560.000000  2490.000000 \n...","image_width":null,"image_height":null}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Cryo electron microscopy of tau filaments from sporadic Alzheimer's disease brain","principal_investigator":[{"author_orcid":"0000-0002-8176-2618","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":null,"town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"CB2 0QH","telephone":null,"fax":null,"first_name":"Benjamin","last_name":"Falcon","email":"bfalcon [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10230"},{"author_orcid":null,"middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":null,"town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"CB2 0QH","telephone":null,"fax":null,"first_name":"Michel","last_name":"Goedert","email":"mg [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10230"}],"status":"REL","deposition_date":"2018-10-17","release_date":"2019-02-20","obsolete_date":null,"update_date":"2021-08-06","corresponding_author":{"author":{"author_orcid":"0000-0002-0462-6540","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":null,"town_or_city":"Cambridge","state_or_province":null,"post_or_zip":"CB2 0QH","first_name":"Sjors","last_name":"Scheres","country":"United Kingdom"}},"authors":[{"author":{"name":"Falcon B","author_orcid":"0000-0002-8176-2618"}},{"author":{"name":"Zhang W","author_orcid":null}},{"author":{"name":"Schweighauser M","author_orcid":"0000-0002-1848-1610"}},{"author":{"name":"Murzin AG","author_orcid":null}},{"author":{"name":"Vidal R","author_orcid":"0000-0002-5803-3871"}},{"author":{"name":"Garringer HJ","author_orcid":null}},{"author":{"name":"Ghetti B","author_orcid":"0000-0002-1842-8019"}},{"author":{"name":"Scheres SHW","author_orcid":"0000-0002-0462-6540"}},{"author":{"name":"Goedert M","author_orcid":"0000-0002-5214-7886"}}],"cross_references":["EMD-0259"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Falcon B","author_orcid":"0000-0002-8176-2618"},{"name":"Zhang W","author_orcid":null},{"name":"Schweighauser M","author_orcid":"0000-0002-1848-1610"},{"name":"Murzin AG","author_orcid":null},{"name":"Vidal R","author_orcid":"0000-0002-5803-3871"},{"name":"Garringer HJ","author_orcid":null},{"name":"Ghetti B","author_orcid":"0000-0002-1842-8019"},{"name":"Scheres SHW","author_orcid":"0000-0002-0462-6540"},{"name":"Goedert M","author_orcid":"0000-0002-5214-7886"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold","volume":"136","country":"","first_page":"699","last_page":"708","year":"2018","language":"English","doi":"10.1007/s00401-018-1914-z","pubmedid":"30276465","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Acta neuropathologica","journal_abbreviation":"Acta Neuropathol.","issue":"5","preprint":false}],"dataset_size":"27.0 GB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["6hre"],"entry_doi":"10.6019/EMPIAR-10230"}}