{"EMPIAR-10194":{"imagesets":[{"segmentations":[],"name":"Unaligned multi-frame micrographs of human gamma-secretase","directory":"data","category":"micrographs - multiframe","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":2925,"frames_per_image":20,"frame_range_min":1,"frame_range_max":20,"voxel_type":"32 BIT FLOAT","pixel_width":1.4,"pixel_height":1.4,"micrographs_file_pattern":null,"picked_particles_file_pattern":null,"picked_particles_directory":null,"details":"Coordinates for the 412,272 particles used for polishing are in shiny_412272_data.star. Coordinates for the 159,549 particles used for the final 3.4A refinement are in shiny_159549_data.star. Both star files are in RELION format and also contain other metadata necessary for refinement in RELION.","image_width":"7420","image_height":"7420"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"An atomic structure of human gamma-secretase","principal_investigator":[{"author_orcid":"0000-0002-0462-6540","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","telephone":null,"fax":null,"first_name":"Sjors","last_name":"Scheres","email":"scheres [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10194"}],"status":"REL","deposition_date":"2018-05-31","release_date":"2018-06-20","obsolete_date":null,"update_date":"2021-08-24","corresponding_author":{"author":{"author_orcid":"0000-0002-0462-6540","middle_name":null,"organization":"MRC Laboratory of Molecular Biology","street":"Francis Crick Avenue","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","first_name":"Sjors","last_name":"Scheres","country":"United Kingdom"}},"authors":[{"author":{"name":"Bai XC","author_orcid":"0000-0002-4234-5686"}},{"author":{"name":"Yan C","author_orcid":null}},{"author":{"name":"Yang G","author_orcid":null}},{"author":{"name":"Lu P","author_orcid":null}},{"author":{"name":"Ma D","author_orcid":null}},{"author":{"name":"Sun L","author_orcid":null}},{"author":{"name":"Zhou R","author_orcid":null}},{"author":{"name":"Scheres SHW","author_orcid":"0000-0002-0462-6540"}},{"author":{"name":"Shi Y","author_orcid":null}}],"cross_references":["EMD-3061"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Bai XC","author_orcid":"0000-0002-4234-5686"},{"name":"Yan C","author_orcid":null},{"name":"Yang G","author_orcid":null},{"name":"Lu P","author_orcid":null},{"name":"Ma D","author_orcid":null},{"name":"Sun L","author_orcid":null},{"name":"Zhou R","author_orcid":null},{"name":"Scheres SHW","author_orcid":"0000-0002-0462-6540"},{"name":"Shi Y","author_orcid":null}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"An atomic structure of human γ-secretase","volume":"525","country":"","first_page":"212","last_page":"217","year":"2015","language":"English","doi":"10.1038/nature14892","pubmedid":"26280335","details":"The micrographs are gain-corrected Falcon-II (integrating mode) movies. A RELION STAR file with the particles used to calculate the 3.4A structure reported in the original paper is also included.","book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":"7568","preprint":false}],"dataset_size":"11.7 TB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["5a63"],"entry_doi":"10.6019/EMPIAR-10194"}}