{"EMPIAR-10180":{"imagesets":[{"segmentations":[],"name":"Polished parcitles","directory":"data","category":"picked particles - single frame - processed","header_format":"MRCS","data_format":"MRCS","num_images_or_tilt_series":327490,"frames_per_image":1,"frame_range_min":null,"frame_range_max":null,"voxel_type":"32 BIT FLOAT","pixel_width":1.699,"pixel_height":1.699,"micrographs_file_pattern":null,"picked_particles_file_pattern":null,"picked_particles_directory":null,"details":"Shiny particles after particle polishing used for the Nature paper were further down-sampled to 1.699 Å/px and windowed to 320 px. These particles were used in the Multibody paper.\n\nThe particle STAR file after consensus refinement, masks and initial references for four bodies and a body STAR file are also included. Readers can reproduce the multibody refinement in the paper using these inputs.","image_width":"320","image_height":"320"}],"workflow_file":null,"grant_references":[],"version_history":[],"title":"Structure of a pre-catalytic spliceosome","principal_investigator":[{"author_orcid":"0000-0002-0462-6540","middle_name":"HW","organization":"MRC laboratory of Molecular Biology","street":"Francis Crick Avenue, Cambridge Biomedical Campus","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","telephone":null,"fax":null,"first_name":"Sjors","last_name":"Scheres","email":"scheres [at] mrc-lmb.cam.ac.uk","country":"United Kingdom","entry":"EMPIAR-10180"}],"status":"REL","deposition_date":"2018-03-27","release_date":"2018-05-30","obsolete_date":null,"update_date":"2018-08-30","corresponding_author":{"author":{"author_orcid":"0000-0002-0462-6540","middle_name":"HW","organization":"MRC laboratory of Molecular Biology","street":"Francis Crick Avenue, Cambridge Biomedical Campus","town_or_city":"Cambridge","state_or_province":"Cambridgeshire","post_or_zip":"CB2 0QH","first_name":"Sjors","last_name":"Scheres","country":"United Kingdom"}},"authors":[{"author":{"name":"Plaschka C","author_orcid":null}},{"author":{"name":"Lin PC","author_orcid":null}},{"author":{"name":"Nagai K","author_orcid":"0000-0003-1785-6510"}},{"author":{"name":"Nakane T","author_orcid":"0000-0003-2697-2767"}},{"author":{"name":"Kimanius D","author_orcid":"0000-0002-2662-6373"}},{"author":{"name":"Lindahl E","author_orcid":"0000-0002-2734-2794"}},{"author":{"name":"Scheres SHW","author_orcid":"0000-0002-0462-6540"}}],"cross_references":["EMD-3686","EMD-3688","EMD-3687","EMD-3682","EMD-3684","EMD-3685","EMD-3683"],"biostudies_references":[],"idr_references":[],"empiar_references":[],"citation":[{"authors":[{"name":"Plaschka C","author_orcid":null},{"name":"Lin PC","author_orcid":null},{"name":"Nagai K","author_orcid":"0000-0003-1785-6510"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Structure of a pre-catalytic spliceosome","volume":"546","country":"","first_page":"617","last_page":"621","year":"2017","language":"English","doi":"10.1038/nature22799","pubmedid":"28530653","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"Nature","journal_abbreviation":"Nature","issue":"7660","preprint":false},{"authors":[{"name":"Nakane T","author_orcid":"0000-0003-2697-2767"},{"name":"Kimanius D","author_orcid":"0000-0002-2662-6373"},{"name":"Lindahl E","author_orcid":"0000-0002-2734-2794"},{"name":"Scheres SH","author_orcid":"0000-0002-0462-6540"}],"editors":[],"published":true,"j_or_nj_citation":true,"title":"Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION","volume":"7","country":"United Kingdom","first_page":null,"last_page":null,"year":"2018","language":"English","doi":"10.7554/eLife.36861","pubmedid":"29856314","details":null,"book_chapter_title":null,"publisher":null,"publication_location":null,"journal":"eLife","journal_abbreviation":"Elife","issue":null,"preprint":false}],"dataset_size":"126.5 GB","experiment_type":"EMDB","scale":null,"related_pdb_entries":["5nrl"],"entry_doi":"10.6019/EMPIAR-10180"}}