Cryo-EM Structure of RyR1 + AMP

Human L-type voltage-gated calcium channel Cav1.2 (CABAD Map 1, Consensus Map)

H. neapolitanus carboxysomal rubisco/CsoSCA-peptide (1-50)complex

Structure of inhibitor 16d-bound SPNS2

Cryo-EM structure of U46619-bound ABCC4

CryoEM structure of Ku heterodimer bound to DNA

RNA polymerase III pre-initiation complex melting complex 2

Cryo-EM structure of Ferritin 2 from Caenorhabditis elegans, FTN-2

OCT4 and MYC-MAX co-bound to a nucleosome

Cryo-EM Structure of RyR1

Human CCC complex

SARS-CoV-2 XBB.1 spike glycoprotein (closed-1 state)

Cryo-EM structure of ATP-U46619-bound ABCC4

III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6

Toroidal Dps-DNA assembly

Cryo-EM structure of the human Sec61 complex inhibited by cotransin

Dps-DNA filament-like assembly

Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)

RNA polymerase III pre-initiation complex melting complex 3

HK97 Prohead II as part of a DNA packaging complex

CryoEM structure of the pointy tip (proteins pIII/pVI/pVIII) from the f1 filamentous bacteriophage

RNA polymerase III pre-initiation complex open complex 1

Six DNA Helix Bundle nanopore - State 3

Cryo-EM Structure of RyR1 (Local Refinement of TMD)

Cryo-electron tomogram of an extracellular vesicle containing tau filaments isolated from Alzheimer's Disease patient brain

Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class2

Human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine (Segment Map 01)

E. coli 50S assembly intermediate from bL17-depletion strain, class: rl17-B-b1

III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant

28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA

MicroED structure of Proteinase K from lamellae milled from multiple plasma sources

Structure of FFAR1-Gq complex bound to TAK-875

Phospholipase C beta 3 (PLCb3) in solution

Cryo-EM structure of the human Sec61 complex inhibited by eeyarestatin I

RNA polymerase III pre-initiation complex open complex 2

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) in a partially-open apo state (Class 1)

DNA-unbound MutSbeta-ATP complex (bent clamp form)

NuA4 Histone Acetyltransferase complex

Six DNA duplex bundle nanopore - State 2

E. coli BAM complex (BamABCDE) bound to darobactin B

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by cyclotriazadisulfonamide (CADA)

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in intermediate conformer

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (composite)

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by eeyarestatin I

CryoEM reconstruction of tri-specific 298-52-80 Multabody (no symmetry applied)

MutSbeta bound to (CAG)2 DNA (canonical form)

MutSbeta bound to 61bp homoduplex DNA

Paired helical tau filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | PHF Tau

Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein

MutSbeta bound to (CAG)2 DNA (open form)

E. coli 50S intermediate, bL17-depletion strain, class: rl17-E-b1

E. coli 50S intermediate, bL17-depletion strain, class: rl17-B-b2

Human EMC:human Cav1.2 channel complex in GDN detergent (ECAB Map 2, Consensus Map)

Human CCC complex

Cryo-EM Structure of RyR1 + ADP

Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex

Yeast cytoplasmic pre-40S ribosome biogenesis complex with deubiquitinating enzyme Otu2

Structure of FFAR1-Gq complex bound to TAK-875 in a lipid nanodisc

HK97 large terminase packaging complex

Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain

Human SLC26A3 in complex with Tenidap

E. coli 50S intermediate, bL17-depletion strain, class: rl17-E-b2

Structure of FFAR1-Gq complex bound to DHA

Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain (Individual 1)

DNA-unbound MutSbeta-ATP complex (straight clamp form)

HK97 Portal Protein In situ (prohead II)

Human EMC:human Cav1.2 channel complex in GDN detergent (Segment map 02)

E. coli 50S intermediate, deaD deletion strain, class: dead-C-a1

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (consensus)

Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640 - C2 refinement

Cannabinoid Receptor 1/G protein complex, Global Refinement

Cryo-EM structure of aspirin-bound ABCC4

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by apratoxin F

Cryo-EM structure of the human Sec61 complex inhibited by ipomoeassin F

Cryo-EM Structure of RyR1 + Adenine

Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine (CABAD Map 2)

CLOCK-BMAL1 bound to a nucleosome at SHL -6.2

Mycobacterium phage Patience

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) in a partially-open apo state (Class 2)

Atomic model of the core modifying region of human fatty acid synthase in complex with TVB-2640

Cryo-EM map 3.8 angstroms of CLOCK-BMAL1 bound to a nuclesomal E-box at position SHL-6.2

CryoEM structure of the round tip (proteins pVII/pVIII/pIX) from the f1 filamentous bacteriophage

Cryo-EM structure of dipyridamole-bound ABCC4

SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (1-up state)

Cryo-EM Structure of RyR1 + Adenosine (Local Refinement of TMD)

DNA-free open form of MutSbeta

Six DNA Helix Bundle nanopore - State 1

in vitro reconstituted yeast 40S ribosome complex with deubiquitinating enzyme Otu2 bound to ubiquitinated eS7 - body 2 (40S head)

Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex - body 1

Human mitochondrial DNA polymerase gamma ternary complex with GC basepair

Human EMC:human Cav1.2 channel complex in GDN detergent (ECAB Map 1, Consensus Map)

MutSbeta bound to homoduplex plasmid DNA

Cryo-EM Structure of RyR1 + cAMP

MAX-MAX bound to a nucleosome at SHL+5.1 and SHL-6.9.

Cryo-EM structure of apo-form ABCC4

Phospholipase C beta 3 (PLCb3) in complex with Gbg on liposomes

CryoEM structure of the central filamentous region of the f1 filamentous bacteriophage, consisting of the major capsid protein pVIII

Local refinement map of Otu2 C-terminal domain bound to ubiquitinated eS7 on yeast 40S ribosome

Cannabinoid Receptor 1/G protein complex, local refinement

RNA polymerase III pre-initiation complex closed complex 2

Six DNA Helix Bundle nanopore - State 5

Structure of the TRAP complex with the Sec translocon and a translating ribosome

CLOCK-BMAL1 bound to a nucleosome SHL+5.8 (consensus map)

CryoEM reconstruction of the tri-specific 298-52-80 Multabody (octahedral symmetry applied)

Cryo-EM structure of the human Sec61 complex in a partially-open apo state (Class 1)

E. coli 50S intermediate, bL17-depletion strain, class: rl17-B-b3

CryoET of HIV-2 Immature Particles

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (local refinement of subunit A and primer/template DNA)

Cryo-EM structure of human k-opioid receptor-Gi complex

E. coli 50S intermediate, bL17-depletion strain, class: rl17-B-b3

Cryo-EM structure of gMCM8/9 helicase

Cryo-EM Structure of biliverdin-bound mitochondrial ABC transporter ABCB10 from Biortus

CLOCK-BMAL1 bound to a nucleosome SHL+5.8 (focus refinement with CLOCK-BMAL1 PAS domains masked)

Cryo-EM structure of the human Sec61 complex inhibited by decatransin

Cryo-EM map of MYC-MAX-OCT4-LIN28 complex

Cryo-EM structure of the human Sec61 complex in a partially-open apo state (Class 2)

Six DNA Helix Bundle nanopore - State 4

CLOCK-BMAL1 bound to the native Por enhancer nucleosome at 3.8 angstrom resolution

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by ipomoeassin F (Class 1)

Coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor

Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2

Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD)

Cryo-EM Structure of RyR1 + ATP-gamma-S

Cryo-EM Structure of RyR1 + ATP-gamma-S (Local Refinement of TMD)

Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1

CLOCK-BMAL1 bound to a nucleosome SHL+5.8

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by cotransin

Cryo-EM Structure of RyR1 + cAMP (Local Refinement of TMD)

Local refinement map of Otu2 N-terminal domain bound to yeast 40S ribosome

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in replication conformer

E. coli 50S intermediate, deaD deletion strain, class: dead-B-b1

HK97 DNA packaging complex

Human SLC26A3 in complex with UK5099

Human EMC:human Cav1.2 channel complex (Segment map 01)

SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (2-up state)

Cryo-EM Structure of RyR1 + Adenosine

Human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine (Segment Map 02)

Cryo-EM structure of C3aR-Gi-scFv16 bound with E7 peptide

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by decatransin

Cannabinoid Receptor 1-G Protein Complex

Phospholipase C beta 3 (PLCb3) in complex with Gbg on lipid nanodiscs

MYC-MAX bound to a nucleosome at SHL+5.8

Structure of a human EMC:human Cav1.2 channel complex in GDN detergent (ECAB Map 3)

SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 focused on RBD-ACE2 interface

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by mycolactone

CLOCK-BMAL1 bound to the native Por nucleosome

Cryo-EM structure of the human Sec61 complex inhibited by mycolactone

E. coli BAM complex (BamABCDE) wild-type

RNA polymerase III pre-initiation complex melting complex 1

SARS-CoV-2 XBB.1 spike glycoprotein (closed-2 state)

Cryo-EM structure of the human Sec61 complex inhibited by cyclotriazadisulfonamide (CADA)

Cryo-EM structure of human TRPV6 in the open state

Cryo-EM Structure of RyR1 + ADP (Local Refinement of TMD)

E. coli 50S intermediate, bL17-depletion strain, class: rl17-C-b1

E. coli 50S intermediate, bL17-depletion strain, class: rl17-E-b10

Cryo-EM map of chimeric Sec complex (human Sec61 and yeast Sec63-71-72) inhibited by ipomoeassin F (Class 2)

Atomic model of the core modifying region of human fatty acid synthase

HK97 portal/large terminase complex

Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F

Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD)