10,000 Entries in a Year
January 23, 2026
The EMDB and wwPDB have reached a historic milestone, releasing 10,000 EMDB entries in a single year. The release data can be viewed here.
The rate of release of 3DEM data to the public continues at an extraordinary pace. For the first time the wwPDB has seen the release of 10,000 entries from the EMDB in just a single year. To put this in context, in 2019 the EMDB stood at 10,000 entries in total, after 17 years of growth. Now in 2025, due to the current volume of data release, the archive has surpassed 50,000 total entries.
This rapid growth is a testament to the hard work of the community which the wwPDB endeavors to support. It also highlights the ongoing challenge the community is facing with ever more data created requiring streamlined deposition, processing, curation, peer-review, and sustainable & scalable archiving practices. We are excited to continue to be part of structural biology history.
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KICSTOR-GATOR1 complex (SZT2 [1-1330], NPRL2, NPRL3, DEPDC5) focused refinement.
Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Primidone
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 1
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (ATPase part)
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Consensus map)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of ARP module)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of nucleosome+OCT4/SOX2 part)
Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Isosakuranetin
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Consensus map)
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Focused refinement of BAF)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2 (Consensus map)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2 (Focused refinement of BAF part)
Focused refinement map on N-terminus of mouse TRPM3 alpha 2 in complex with antagonist Ononetin
Cryo-EM composite structure of mouse TRPM3 alpha 2 in complex with antagonist Ononetin
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6
Cryo-EM structure of mouse TRPM3 alpha 2 in with agonists CIM-0216 and Pregnenolone sulfate (PregS)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focused refinement of nucleosome+OCT4/SOX2 part)
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of BAF BASE+ARM+HEAD)
Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Ononetin
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of nucleosome part)
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Focused refinement of nucleosome and ATPase lobes)
Entamoeba histolytica Gal/GalNAc lectin in presence of monoclonal antibody CP33-H/L-LA22, mode I
Entamoeba histolytica Gal/GalNAc lectin in presence of monoclonal antibody CP33-H/L-LA22, mode 2
Entamoeba histolytica Gal/GalNAc lectin bound to monoclonal antibody CP33-H/L-LA22
Entamoeba histolytica Gal/GalNAc lectin bound to galactose, mode 1
CRYO-EM STRUCTURE OF THE YEAST RESPIRATORY COMPLEX II WITH THE INHIBITOR BIXAFEN
Activated 9-subunit COP9 signalosome and neddylated SCF (SKP1-SKP2-CKS1) complex structure
Entamoeba histolytica Gal/GalNAc lectin bound to galactose, mode 3
Entamoeba histolytica Gal/GalNAc lectin in presence of monoclonal antibody CP33-H/L-LA22, mode 3
PhiC31 integrative synapse: attB x attP with an S12A integrase variant
Entamoeba histolytica Gal/GalNAc lectin bound to galactose, mode 2
PhiC31 excisive synapse; attL x attL with an integraseS12A-RDF protein fusion
PhiC31 integrase-attB-attP synaptic complex: attB-bound dimer subregion
Structure of the MAP2K MEK1 in an inactive conformation in complex with its substrate MAPK ERK2
Structure of the MAP2K MEK1 in an active conformation in complex with its substrate MAPK ERK2
PhiC31 integrase-attB-attP synaptic complex: attP-bound dimer subregion
CryoEM structure of GFP-like protein from Aequorea coerulescens with Trimbody
The structure of mCAT1 in complex with its substrate ornithine and the RBD of FrMLV.
Target DNA-bound type I-F3 TniQ-Cascade of Vibrio parahaemolyticus in partial R-loop state
Target DNA-bound type I-F3 TniQ-Cascade of Vibrio parahaemolyticus in full R-loop state 1
Target DNA-bound type I-F3 TniQ-Cascade of Vibrio parahaemolyticus in full R-loop state 2
Cryo-EM structure of the multi-component acyltransferase complex MucABC from Streptococcus macacae at a stoichiometric ratio of 4:2:2
Cryo-EM structure of the multi-component acyltransferase complex MucABC from Streptococcus macacae at a stoichiometric ratio of 4:4:4
Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of 20B8
The structure of outer peripheral region in the phage phiKZ baseplate complex
Structure of the inner peripheral region in the phage phiKZ baseplate complex
In situ structure of radial spoke 2 head in the axoneme of mouse sperm
In situ structure of radial spoke 1 head in the axoneme of mouse sperm
In situ structure of radial spoke 3 head in the axoneme of mouse sperm
In situ structure of radial spoke 3 base in the axoneme of mouse sperm
In situ structure of radial spoke 2 base in the axoneme of mouse sperm
In situ structure of radial spoke 1 base in the axoneme of mouse sperm
Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of 10G2
Structure of mammalian RNA polymerase II stalled by Actinomycin D at the N-1 position.
CryoEM structure of anti-MHC-I Fab B1.23.2 complex with HLA-B44:05
Structure of full length AMPA receptor GluA2 and auxiliary subunit TARP gamma-2 in complex with anti-miR 17 oligonucleotide RGLS4326
Structure of AMPA receptor GluA2 and auxiliary subunit TARP gamma-2 (LBD-TMD) in complex with anti-miR 17 oligonucleotide RGLS4326
Composite map of in situ structure of the 96-nm repeat DMT in the axoneme of mouse sperm
Consensus map of in situ structure of the 96-nm repeat DMT in the axoneme of mouse sperm
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H47 CD19 CAR construct
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H15 CD19 CAR construct
Ligand-binding and transmembrane domains for GluK2-2xNeto2 in the apo state
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H15 CD19 CAR construct
Ligand-binding and transmembrane domains for GluK2-1xNeto2 in the apo state
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H47 CD19 CAR construct
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H8 CD19 CAR construct, (sample2, region3).
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H8 CD19 CAR construct, (sample2, region2).
Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H8 CD19 CAR construct, (sample 1).
Cryo-EM structure of amyloid fibrils extracted from the heart of a variant ATTRv-A25S amyloidosis
Focused refinement of the prefusion F glycoprotein ectodomain of Nipah virus in complex with DS90 nanobody
Cryo-EM structure of amyloid fibril isolated from the kidney of a variant Alect2-I40V amyloidosis patient
Cryo-EM structure of amyloid fibril extracted from the heart of a variant ATTR D38A amyloidosis patient
Cryo-EM structure of amyloid fibril isolated from the kidney of a variant ALECT2-I40V amyloidosis patient
Cryo-EM structure of amyloid fibril isolated from the kidney of a variant ALECT2-I40V amyloidosis patient
Structure of Nanchung-Inactive-Calmodulin in complex with Nicotinamide
Structure of MurJ in complex with single gene lysis protein from phage M
Structure of Nanchung-Inactive-Calmodulin in complex with Afidopyropen, EDTA
Structure of Nanchung-Inactive-Calmodulin in complex with Afidopyropen and calcium
Structure of MurJ in complex with single gene lysis protein from phage PP7
Structure of MurJ in complex with single gene lysis protein from phage Changjiang3
Structure of Nanchung-Inactive-Calmodulin in complex with Nicotinamide, EDTA