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Current Database

  • EMDB [1828]
  • EMPIAR [3]

Current status

  • REL [1831]

Sample type

  • Complex [1558]
  • Protein [1412]
  • Ligand [821]
  • Virus [193]
  • RNA [152]
  • DNA [149]
  • Cellular component [67]
  • Sample [27]
  • Cell [19]
  • Other [7]
  • Tissue [6]

Organism

  • Homo sapiens [600]
  • Escherichia coli [159]
  • Human immunodeficiency virus 1 [137]
  • Mus musculus [126]
  • Synthetic construct [122]
  • Severe acute respiratory syndrome coronavirus [112]
  • Escherichia coli [65]
  • Saccharomyces cerevisiae [47]
  • Oryctolagus cuniculus [39]
  • Rattus norvegicus [37]
  • Sus scrofa [35]
  • Arabidopsis thaliana [29]
  • Polytomella sp. pringsheim 198.80 [29]
  • Rous sarcoma virus [28]
  • Enterobacteria phage t4 [27]
  • Bos taurus [25]
  • Lama glama [24]
  • Saccharomyces cerevisiae [22]
  • Severe acute respiratory syndrome coronavirus [21]
  • Influenza a virus [18]
  • Human coronavirus hku1 [18]
  • Drosophila melanogaster [17]
  • Primate t-lymphotropic virus 1 [15]
  • Foot-and-mouth disease virus [15]
  • Spinacia oleracea [15]
  • Xenopus laevis [15]
  • Mycoplasma pneumoniae [14]
  • Equine infectious anemia virus [13]
  • Caenorhabditis elegans [13]
  • Zaire ebolavirus [12]
  • Middle east respiratory syndrome-related coronavirus [12]
  • Bacillus subtilis [12]
  • Squalus acanthias [12]
  • Gallus gallus [12]
  • Chlamydomonas reinhardtii [11]
  • Chaetomium thermophilum [11]
  • Enterobacteria phage m13 [10]
  • Photorhabdus luminescens [10]
  • Aquifex aeolicus [10]
  • Yarrowia lipolytica [9]
  • Escherichia coli [9]
  • Macaca mulatta [9]
  • Human cytomegalovirus [8]
  • Brome mosaic virus [7]
  • Staphylococcus epidermidis [7]
  • Rhodobacter capsulatus [7]
  • Escherichia virus qbeta [7]
  • Plasmodium falciparum [7]
  • Shewanella oneidensis [7]
  • Adeno-associated dependoparvovirus a [6]
  • Human metapneumovirus [6]
  • Aquifex aeolicus [6]
  • Vibrio cholerae [6]
  • Danio rerio [6]
  • Synechocystis sp. pcc 6803 [5]
  • Murine leukemia virus [5]
  • Staphylococcus epidermidis [5]
  • Thermococcus gammatolerans [5]
  • Dna molecule [5]
  • Acinetobacter baylyi [5]
  • (no species) [5]
  • Synechocystis sp. (strain pcc 6714) [4]
  • Simian immunodeficiency virus [4]
  • Barley stripe mosaic virus [4]
  • Mycobacterium tuberculosis [4]
  • Geobacter sulfurreducens [4]
  • Escherichia phage lambda [4]
  • Phage m13mp18 [4]
  • Thermus thermophilus [4]
  • Dictyostelium discoideum [4]
  • Schizosaccharomyces pombe [4]
  • (no species) [4]
  • Aequorea victoria [4]
  • Branchiostoma belcheri [4]
  • Staphylococcus aureus [4]
  • Pseudomonas phage phi6 [3]
  • (no species) [3]
  • Acidaminococcus sp. (strain bv3l6) [3]
  • Mason-pfizer monkey virus [3]
  • Enterovirus c [3]
  • Hepatovirus a [3]
  • Tobacco mosaic virus [3]
  • Chaetomium thermophilum [3]
  • Aliarcobacter butzleri [3]
  • Rotavirus a [3]
  • Influenza a virus [3]
  • Streptococcus pneumoniae [3]
  • Puccinia graminis [3]
  • Klebsiella pneumoniae [3]
  • Trichoplusia ni [3]
  • Xenopus tropicalis [3]
  • Desulfovibrio vulgaris [3]
  • Salmonella enterica [3]
  • Thauera chlorobenzoica [3]
  • Epstein-barr virus (strain gd1) [2]
  • Rabies lyssavirus [2]
  • Teetrevirus t3luria [2]
  • Japanese encephalitis virus [2]
  • Synechocystis sp. pcc 6803 [2]
  • Lassa mammarenavirus [2]

EM Method

  • Single-particle [1500]
  • Subtomogram averaging [140]
  • Helical reconstruction [121]
  • Tomography [67]

Resolution

  • < 2Å [4]
  • ≥ 2Å and < 3Å [244]
  • ≥ 3Å and < 4Å [767]
  • ≥ 4Å and < 5Å [265]
  • ≥ 5Å and < 6Å [68]
  • ≥ 6Å and < 8Å [157]
  • ≥ 8Å and < 12Å [134]
  • ≥ 12Å and < 16Å [35]
  • ≥ 16Å and < 20Å [35]
  • ≥ 20Å and < 30Å [34]
  • ≥ 30Å [17]

Model molecular weight

  • 0-50 kDa [22]
  • 50-100 kDa [51]
  • 100-250 kDa [343]
  • 250-500 kDa [447]
  • 500-1000 kDa [233]
  • 1-2 MDa [62]
  • 2-5 MDa [56]
  • 5-10 MDa [13]
  • > 10 MDa [23]

Release Date

  • 2025 [185]
  • 2024 [184]
  • 2023 [283]
  • 2022 [229]
  • 2021 [252]
  • 2020 [202]
  • 2019 [121]
  • 2018 [118]
  • 2017 [139]
  • 2016 [93]
  • 2015 [9]
  • 2014 [7]
  • 2013 [7]
  • 2011 [2]

Author by name

  • Briggs JAG [95]
  • Ward AB [85]
  • Kwong PD [79]
  • Schur FKM [76]
  • Dick RA [70]
  • Gorman J [59]
  • Cottrell CA [57]
  • Obr M [56]
  • Stuart DI [54]
  • Mclellan JS [53]
  • Krausslich HG [51]
  • Zhang B [51]
  • Sobolevsky AI [50]
  • Fry EE [48]
  • Kuhlbrandt W [46]
  • Darst SA [45]
  • Dietz H [45]
  • Pallesen J [45]
  • Wrapp D [45]
  • Liu T [43]
  • Thader A [43]
  • Graham BS [42]
  • Mills DJ [42]
  • Zhang X [41]
  • Chen X [40]
  • Kollman JM [40]
  • Wang N [40]
  • Lyumkis D [39]
  • Zhang Y [39]
  • Fandrich M [38]
  • Glass B [38]
  • Mascola JR [38]
  • Ren J [38]
  • Schmidt M [38]
  • Turner HL [38]
  • Nogales E [37]
  • Zhou T [37]
  • Corbett KS [36]
  • Johnson MC [36]
  • Ricana CL [36]
  • Scheres SHW [36]
  • Vogt VM [36]
  • Doria-rose NA [35]
  • Langer J [35]
  • Murphy BJ [35]
  • Briggs JA [34]
  • Chen J [34]
  • Feathers JR [34]
  • Hagen WJ [34]
  • Kohler F [34]
  • Qu K [34]
  • Duyvesteyn HME [33]
  • Kirchdoerfer RN [33]
  • Shapiro L [33]
  • Torres JL [33]
  • Wilson IA [33]
  • Liu C [32]
  • Olia AS [32]
  • Potter CS [32]
  • Carragher B [31]
  • Chuang GY [31]
  • Feigl E [31]
  • Mattei S [31]
  • Rawi R [31]
  • Shen CH [31]
  • Wang S [31]
  • Diamond MS [29]
  • Faendrich M [29]
  • Grigorieff N [29]
  • Klusch N [29]
  • Yildiz O [29]
  • Zhou D [29]
  • Honemann MN [28]
  • Klanschnig M [28]
  • Li Z [28]
  • Mongkolsapaya J [28]
  • Nikulin N [28]
  • Screaton GR [28]
  • Yelshanskaya MV [28]
  • De Val N [28]
  • Liu Y [27]
  • Supasa P [27]
  • Tsybovsky Y [27]
  • Williamson JR [27]
  • Xiong X [27]
  • Clare DK [26]
  • Davis JH [26]
  • Dejnirattisai W [26]
  • Kotecha A [26]
  • Kube M [26]
  • Mentzer AJ [26]
  • Shi J [26]
  • Temperton N [26]
  • Wang J [26]
  • Yu H [26]
  • Chiu PL [25]
  • Moores CA [25]
  • Mueller AU [25]
  • Chen RE [24]
  • Funke JJ [24]

Author by ORCID

  • Briggs JAG [81]
  • Kwong PD [76]
  • Schur FKM [63]
  • Gorman J [53]
  • Mclellan JS [53]
  • Kuhlbrandt W [46]
  • Wrapp D [45]
  • Pallesen J [45]
  • Krausslich HG [44]
  • Darst SA [40]
  • Mills DJ [40]
  • Dietz H [37]
  • Scheres SHW [36]
  • Cottrell CA [36]
  • Ricana CL [36]
  • Murphy BJ [35]
  • Langer J [35]
  • Hagen WJ [34]
  • Kollman JM [34]
  • Briggs JA [34]
  • Qu K [33]
  • Torres JL [32]
  • Mattei S [31]
  • Ren J [30]
  • Grigorieff N [29]
  • Stuart DI [29]
  • Zhou D [29]
  • Klusch N [29]
  • Klanschnig M [28]
  • Kotecha A [26]
  • Mentzer AJ [26]
  • Xiong X [26]
  • Temperton N [26]
  • Davis JH [26]
  • Moores CA [25]
  • Chiu PL [25]
  • Wang N [25]
  • Mueller AU [25]
  • Nagel-yuksel B [24]
  • Willner EM [24]
  • Nguyen THD [23]
  • Zhou T [23]
  • Duyvesteyn HME [23]
  • Williamson JR [23]
  • Sobolevsky AI [22]
  • Li Z [22]
  • Nadezhdin KD [22]
  • Neuberger A [22]
  • Liu C [22]
  • Fry EE [21]
  • Nogales E [21]
  • Raunser S [20]
  • Ghanim GE [20]
  • Wang B [20]
  • Tan A [20]
  • Hall DR [20]
  • Howe A [20]
  • Paterson NG [20]
  • Stokes DL [19]
  • Vonck J [19]
  • Tan YZ [19]
  • Huiskonen JT [19]
  • Chen J [19]
  • Ciazynska KA [19]
  • Carter AP [18]
  • Nitz M [18]
  • Wong AHM [18]
  • Gilbert M [18]
  • Rini JM [18]
  • Chen X [18]
  • Yu H [18]
  • Boesen T [18]
  • Dick RA [18]
  • Jin M [18]
  • Walter TS [17]
  • Twomey EC [17]
  • Nissen P [17]
  • Korostelev AA [17]
  • Saibil HR [16]
  • Lu JM [16]
  • Cerutti G [16]
  • Wan W [16]
  • Molina N [16]
  • Ge J [15]
  • Campbell EA [15]
  • Goehring A [15]
  • Gouaux E [15]
  • Schmidt M [15]
  • Elferich J [15]
  • Yang H [15]
  • Meier-credo J [15]
  • Fandrich M [15]
  • Matsui A [15]
  • Chernikova D [15]
  • Hagen WJH [14]
  • Ward AB [14]
  • Loveland AB [14]
  • Brown A [14]
  • Grant T [14]
  • Ke Z [14]

Journal

  • NAT COMMUN [326]
  • PNAS [156]
  • NATURE [122]
  • TO BE PUBLISHED [120]
  • NAT STRUCT MOL BIOL [113]
  • SCIENCE [112]
  • ELIFE [95]
  • BIORXIV [88]
  • SCI ADV [87]
  • CELL [69]
  • STRUCTURE [56]
  • CELL REP [54]
  • COMMUN BIOL [46]
  • MOL CELL [46]
  • NUCLEIC ACIDS RES [36]
  • CELL HOST MICROBE [31]
  • SCI REP [27]
  • EMBO J [26]
  • J MOL BIOL [26]
  • PLOS PATHOG [24]
  • J BIOL CHEM [23]
  • J VIROL [18]
  • J STRUCT BIOL [16]
  • NAT MICROBIOL [13]
  • J EXP MED [11]
  • PROTEIN SCI [10]
  • CURR BIOL [9]
  • FRONT IMMUNOL [9]
  • ACTA CRYSTALLOGR D STRUCT BIOL [8]
  • CELL REP PHYS SCI [8]
  • NAT CHEM BIOL [8]
  • J CELL BIOL [7]
  • SCI TRANSL MED [7]
  • COMMUN CHEM [5]
  • IMMUNITY [5]
  • INT J MOL SCI [5]
  • NAT PLANTS [5]
  • RES SQ [5]
  • DEV CELL [4]
  • EMBO REP [4]
  • NAT MED [4]
  • NAT METHODS [4]
  • NAT NANOTECHNOL [4]
  • NEURON [4]
  • NPJ DRUG DISCOV [4]
  • SMALL [4]
  • ACS NANO [3]
  • BIOPHYS REV [3]
  • FEBS LETT [3]
  • MBIO [3]
  • METHODS [3]
  • NPJ BIOFILMS MICROBIOMES [3]
  • PROTEIN CELL [3]
  • BIOCHEM J [2]
  • BIOCHEMISTRY [2]
  • BIOMOLECULES [2]
  • BLOOD [2]
  • FRONT CELL INFECT MICROBIOL [2]
  • J.NEUROCHEM. [2]
  • MICROBIOL SPECTR [2]
  • NPJ VACCINES [2]
  • PLOS ONE [2]
  • SCI SIGNAL [2]
  • VIRUSES [2]
  • ACS CENT SCI [1]
  • ACS INFECT DIS. [1]
  • ACTA NEUROPATHOL [1]
  • ADV STRUCT CHEM IMAGING [1]
  • ANGEW CHEM INT ED ENGL [1]
  • AUTOPHAGY [1]
  • BBA ADV [1]
  • CANCER DISCOV [1]
  • CELL CHEM BIOL [1]
  • CELL DISCOV [1]
  • CELL REP MED [1]
  • COMPUT CRYST NEWSL [1]
  • EMERG MICROBES INFECT [1]
  • FRONT MICROBIOL [1]
  • FRONT MOL BIOSCI [1]
  • HUM MOL GENE [1]
  • J CELL SCI [1]
  • J GEN PHYSIOL [1]
  • J.INORG.BIOCHEM. [1]
  • JOULE [1]
  • MABS [1]
  • MOL BIOL CELL [1]
  • NAT CELL BIOL [1]
  • NAT CHEM [1]
  • NAT MATER [1]
  • PLOS BIOL [1]
  • PNAS NEXUS [1]
  • PROG BIOPHYS MOL BIOL [1]
  • RNA [1]
  • THERANOSTICS [1]

Software

  • RELION [779]
  • CRYOSPARC [619]
  • CTFFIND [175]
  • IMOD [103]
  • GCTF [100]
  • FREALIGN [81]
  • MATLAB [65]
  • AV3 [56]
  • CISTEM [46]
  • TOM TOOLBOX [44]
  • PHENIX [34]
  • DYNAMO [32]
  • APPION [24]
  • WARP [24]
  • CTFPHASEFLIP [21]
  • NOVACTF [21]
  • CTFTILT [19]
  • EMAN [17]
  • XMIPP [17]
  • SUBTOM [16]
  • TOMOALIGN [15]
  • TOM [14]
  • CTFFIND3 [10]
  • EMAN2 [10]
  • FREALIX [10]
  • SPHIRE [10]
  • AMIRA [9]
  • ETOMO [9]
  • SPIDER [9]
  • PEET [8]
  • AMIRAFPM [7]
  • UCSF CHIMERAX [7]
  • SPRING [6]
  • UCSF CHIMERA [6]
  • JSPR [5]
  • CTFFIND4 [4]
  • EMAN, IMAGIC, SPIDER [4]
  • XMIPP, FREALIGN [4]
  • COOT [3]
  • SPARX [3]
  • CHIMERA [2]
  • CRYOLO [2]
  • EMAN, IMAGIC, RELION [2]
  • EMAN2 SPARX [2]
  • GCTF/RELION [2]
  • IMAGIC [2]
  • RELION, CTFFIND3 [2]
  • TOM, AV3 [2]
  • BSOFT [1]
  • CHIMERA, COOT [1]
  • CHIMERA, MDFF [1]
  • CHIMERA, ROSETTA [1]
  • CHIMERA, VMD, MDFF [1]
  • DIREX [1]
  • E2HELIXBOXER.PY [1]
  • EMAN2, SPARX [1]
  • EMCLARITY [1]
  • FREALIGNX [1]
  • I-TASSER, CHIMERA, DIREX [1]
  • IMOD, AV3, TOM, DYNAMO [1]
  • MOTIONCORR2 [1]
  • RELION2.1 [1]
  • RSREF [1]
  • SCIPION [1]
  • SEGREFINETHREED [1]
  • XMIPP, AND, FREALIGN [1]

Microscope

  • FEI TITAN KRIOS [1332]
  • TFS KRIOS [173]
  • FEI TALOS ARCTICA [81]
  • FEI POLARA 300 [57]
  • TFS GLACIOS [57]
  • FEI TECNAI F20 [29]
  • FEI TITAN [20]
  • JEOL 3200FSC [13]
  • FEI TECNAI ARCTICA [12]
  • TFS TALOS [10]
  • TFS TALOS F200C [10]
  • FEI TECNAI 20 [8]
  • FEI TECNAI F30 [8]
  • JEOL CRYO ARM 300 [7]
  • JEOL 3200FS [5]
  • FEI TECNAI 12 [4]
  • JEOL 2010F [1]
  • JEOL 2200FSC [1]
  • JEOL 3000SFF [1]
  • TFS TUNDRA [1]

Electron Source

  • FIELD EMISSION GUN [1817]
  • LAB6 [8]
  • TUNGSTEN HAIRPIN [2]
  • OTHER [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [608]
  • GATAN K3 6K X 4K [405]
  • GATAN K3 BIOQUANTUM 6K X 4K [313]
  • GATAN K2 QUANTUM 4K X 4K [158]
  • FEI FALCON III 4K X 4K [132]
  • FEI FALCON IV 4K X 4K [100]
  • FEI FALCON II 4K X 4K [38]
  • GATAN ULTRASCAN 4000 4K X 4K [13]
  • FEI CETA 4K X 4K [12]
  • GATAN K2 BASE 4K X 4K [9]
  • GATAN K3 BIOCONTINUUM 6K X 4K [8]
  • DIRECT ELECTRON DE-20 5K X 3K [7]
  • GATAN MULTISCAN [5]
  • FEI EAGLE 2K X 2K [4]
  • GENERIC GATAN 4K X 4K [4]
  • TFS FALCON 4I 4K X 4K [4]
  • DIRECT ELECTRON DE-64 8K X 8K [3]
  • GATAN K2 4K X 4K [3]
  • DIRECT ELECTRON APOLLO 4K X 4K [2]
  • GENERIC TVIPS 4K X 4K [2]
  • OTHER [2]
  • TVIPS TEMCAM-F416 4K X 4K [2]
  • DECTRIS ELA 1K X 0.5K [1]
  • DIRECT ELECTRON DE-12 4K X 3K [1]
  • DIRECT ELECTRON DE-16 4K X 4K [1]
  • FEI FALCON I 4K X 4K [1]
  • TVIPS TEMCAM-F816 8K X 8K [1]

EMPIAR Experiment type

  • EMDB [3]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [3]

External links

  • UniProt [1327]
  • PDB [1257]
  • PDBe-Kb [1231]
  • AlphaFold DB [1037]
  • Pfam [997]
  • InterPro [966]
  • Gene Ontology [948]
  • ChEBI [794]
  • ChEMBL [731]
  • DrugBank [576]
  • Complex Portal [348]
  • EMPIAR [213]
  • CATH [39]
  • SCOP2 [37]
  • EMDB [3]
Sort by: Download
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EMD-70826
Composite map
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3D View
Cryo-EM structure of the PI4KA complex bound to an EFR3 interfering nanobody F3IN
Release date: Dec. 3, 2025
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 9ot6
Q-score: 0.347

Suresh S, Shaw AL, Akintola DK, Lunke M, Doerr S, Rohilla P, Balla T, Yip CK, Hansen SD, Cobb JA, Burke JE

J Biol Chem (2025) pp. 110886-110886 [ DOI: doi:10.1016/j.jbc.2025.110886 Pubmed: 41197736 ]

EMD-48183
Download Map
3D View
Antibody fragments from mAb475 and mAb824 bound to the adhesin protein FimH
Release date: Nov. 26, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9me4
Q-score: 0.517

Hvorecny KL, Kollman JM

To Be Published

EMD-48185
Download Map
3D View
Antibody fragments from mAb21, mAb475, and mAb824 bound to the adhesin protein FimH
Release date: Nov. 26, 2025
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9me6
Q-score: 0.573

Hvorecny KL, Kollman JM

To Be Published

EMD-48187
Download Map
3D View
Antibody fragments from mAb21 and mAb475 bound to the fimbrial tip protein, FimH
Release date: Nov. 26, 2025
Resolution: 5.8 Å
EM Method: Single-particle

Hvorecny KL, Kollman JM

To Be Published

EMD-52659
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3D View
A subunit of alpha-1 antitrypsin polymers isolated from ZZ explant liver tissue and decorated with conformationally nonselective Fab 9C5
Release date: Nov. 26, 2025
Resolution: 3.98 Å
EM Method: Single-particle

Aldobiyan I, Elliston ELK, Heyer-Chauhan N, Arold ST, Zhao L, Huntington B, Lowen SM, Orlova EV, Irving JA, Lomas DA

PNAS (2025) 122 pp. e2507535122-e2507535122 [ DOI: doi:10.1073/pnas.2507535122 Pubmed: 41231946 ]

EMD-70462
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3D View
Cryo-EM structure of human exportin-1 conjugated with selinexor and bound to human ASB8 R197A -ELOB/C
Release date: Nov. 26, 2025
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 9ogd
Q-score: 0.571

Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM

bioRxiv (2025) [ Pubmed: 39416201 DOI: doi:10.1101/2024.10.07.617049 ]

EMD-70463
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3D View
Cryo-EM structure of human exportin-1 conjugated with KPT-127 and bound to human ASB8-ELOB/C
Release date: Nov. 26, 2025
Resolution: 3.28 Å
EM Method: Single-particle
Fitted PDBs: 9oge
Q-score: 0.412

Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM

bioRxiv (2025) [ Pubmed: 39416201 DOI: doi:10.1101/2024.10.07.617049 ]

EMD-70464
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3D View
Cryo-EM structure of human exportin-1 conjugated with KPT-UTSW1 and bound to human ASB8-ELOB/C
Release date: Nov. 26, 2025
Resolution: 4.21 Å
EM Method: Single-particle
Fitted PDBs: 9ogf
Q-score: 0.241

Wing CE, Fung HYJ, Kwanten B, Cagatay T, Niesman AB, Jacquemyn M, Gharghabi M, Permentier B, Shakya B, Nandi R, Ready JM, Kashyap T, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM

bioRxiv (2025) [ Pubmed: 39416201 DOI: doi:10.1101/2024.10.07.617049 ]

EMD-71842
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Antibody fragment from mAb824 bound to the adhesin protein FimH.
Release date: Nov. 26, 2025
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9ptm
Q-score: 0.496

Hvorecny KL, Kollman JM

To Be Published

EMD-49373
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CryoEM Structure of De Novo Antibody Fragment scFv 6 with C. difficile Toxin B TcdB
Release date: Nov. 12, 2025
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9nfu
Q-score: 0.453

Bennett NR, Watson JL, Ragotte RJ, Borst AJ, See DL, Weidle C, Biswas R, Yu Y, Shrock EL, Ault R, Leung PJY, Huang B, Goreshnik I, Tam J, Carr KD, Singer B, Criswell C, Wicky BIM, Vafeados D, Garcia Sanchez M, Kim HM, Vazquez Torres S, Chan S, Sun SM, Spear TT, Sun Y, O'Reilly K, Maris JM, Sgourakis NG, Melnyk RA, Liu CC, Baker D

Nature (2025) [ Pubmed: 41193805 DOI: doi:10.1038/s41586-025-09721-5 ]

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Current Database

  • EMDB [1828]
  • EMPIAR [3]

Current status

  • REL [1831]

Sample type

  • Complex [1558]
  • Protein [1412]
  • Ligand [821]
  • Virus [193]
  • RNA [152]
  • DNA [149]
  • Cellular component [67]
  • Sample [27]
  • Cell [19]
  • Other [7]
  • Tissue [6]

Organism

  • Homo sapiens [600]
  • Escherichia coli [159]
  • Human immunodeficiency virus 1 [137]
  • Mus musculus [126]
  • Synthetic construct [122]
  • Severe acute respiratory syndrome coronavirus [112]
  • Escherichia coli [65]
  • Saccharomyces cerevisiae [47]
  • Oryctolagus cuniculus [39]
  • Rattus norvegicus [37]
  • Sus scrofa [35]
  • Arabidopsis thaliana [29]
  • Polytomella sp. pringsheim 198.80 [29]
  • Rous sarcoma virus [28]
  • Enterobacteria phage t4 [27]
  • Bos taurus [25]
  • Lama glama [24]
  • Saccharomyces cerevisiae [22]
  • Severe acute respiratory syndrome coronavirus [21]
  • Influenza a virus [18]
  • Human coronavirus hku1 [18]
  • Drosophila melanogaster [17]
  • Primate t-lymphotropic virus 1 [15]
  • Foot-and-mouth disease virus [15]
  • Spinacia oleracea [15]
  • Xenopus laevis [15]
  • Mycoplasma pneumoniae [14]
  • Equine infectious anemia virus [13]
  • Caenorhabditis elegans [13]
  • Zaire ebolavirus [12]
  • Middle east respiratory syndrome-related coronavirus [12]
  • Bacillus subtilis [12]
  • Squalus acanthias [12]
  • Gallus gallus [12]
  • Chlamydomonas reinhardtii [11]
  • Chaetomium thermophilum [11]
  • Enterobacteria phage m13 [10]
  • Photorhabdus luminescens [10]
  • Aquifex aeolicus [10]
  • Yarrowia lipolytica [9]
  • Escherichia coli [9]
  • Macaca mulatta [9]
  • Human cytomegalovirus [8]
  • Brome mosaic virus [7]
  • Staphylococcus epidermidis [7]
  • Rhodobacter capsulatus [7]
  • Escherichia virus qbeta [7]
  • Plasmodium falciparum [7]
  • Shewanella oneidensis [7]
  • Adeno-associated dependoparvovirus a [6]
  • Human metapneumovirus [6]
  • Aquifex aeolicus [6]
  • Vibrio cholerae [6]
  • Danio rerio [6]
  • Synechocystis sp. pcc 6803 [5]
  • Murine leukemia virus [5]
  • Staphylococcus epidermidis [5]
  • Thermococcus gammatolerans [5]
  • Dna molecule [5]
  • Acinetobacter baylyi [5]
  • (no species) [5]
  • Synechocystis sp. (strain pcc 6714) [4]
  • Simian immunodeficiency virus [4]
  • Barley stripe mosaic virus [4]
  • Mycobacterium tuberculosis [4]
  • Geobacter sulfurreducens [4]
  • Escherichia phage lambda [4]
  • Phage m13mp18 [4]
  • Thermus thermophilus [4]
  • Dictyostelium discoideum [4]
  • Schizosaccharomyces pombe [4]
  • (no species) [4]
  • Aequorea victoria [4]
  • Branchiostoma belcheri [4]
  • Staphylococcus aureus [4]
  • Pseudomonas phage phi6 [3]
  • (no species) [3]
  • Acidaminococcus sp. (strain bv3l6) [3]
  • Mason-pfizer monkey virus [3]
  • Enterovirus c [3]
  • Hepatovirus a [3]
  • Tobacco mosaic virus [3]
  • Chaetomium thermophilum [3]
  • Aliarcobacter butzleri [3]
  • Rotavirus a [3]
  • Influenza a virus [3]
  • Streptococcus pneumoniae [3]
  • Puccinia graminis [3]
  • Klebsiella pneumoniae [3]
  • Trichoplusia ni [3]
  • Xenopus tropicalis [3]
  • Desulfovibrio vulgaris [3]
  • Salmonella enterica [3]
  • Thauera chlorobenzoica [3]
  • Epstein-barr virus (strain gd1) [2]
  • Rabies lyssavirus [2]
  • Teetrevirus t3luria [2]
  • Japanese encephalitis virus [2]
  • Synechocystis sp. pcc 6803 [2]
  • Lassa mammarenavirus [2]

EM Method

  • Single-particle [1500]
  • Subtomogram averaging [140]
  • Helical reconstruction [121]
  • Tomography [67]

Resolution

  • < 2Å [4]
  • ≥ 2Å and < 3Å [244]
  • ≥ 3Å and < 4Å [767]
  • ≥ 4Å and < 5Å [265]
  • ≥ 5Å and < 6Å [68]
  • ≥ 6Å and < 8Å [157]
  • ≥ 8Å and < 12Å [134]
  • ≥ 12Å and < 16Å [35]
  • ≥ 16Å and < 20Å [35]
  • ≥ 20Å and < 30Å [34]
  • ≥ 30Å [17]

Model molecular weight

  • 0-50 kDa [22]
  • 50-100 kDa [51]
  • 100-250 kDa [343]
  • 250-500 kDa [447]
  • 500-1000 kDa [233]
  • 1-2 MDa [62]
  • 2-5 MDa [56]
  • 5-10 MDa [13]
  • > 10 MDa [23]

Release Date

  • 2025 [185]
  • 2024 [184]
  • 2023 [283]
  • 2022 [229]
  • 2021 [252]
  • 2020 [202]
  • 2019 [121]
  • 2018 [118]
  • 2017 [139]
  • 2016 [93]
  • 2015 [9]
  • 2014 [7]
  • 2013 [7]
  • 2011 [2]

Author by name

  • Briggs JAG [95]
  • Ward AB [85]
  • Kwong PD [79]
  • Schur FKM [76]
  • Dick RA [70]
  • Gorman J [59]
  • Cottrell CA [57]
  • Obr M [56]
  • Stuart DI [54]
  • Mclellan JS [53]
  • Krausslich HG [51]
  • Zhang B [51]
  • Sobolevsky AI [50]
  • Fry EE [48]
  • Kuhlbrandt W [46]
  • Darst SA [45]
  • Dietz H [45]
  • Pallesen J [45]
  • Wrapp D [45]
  • Liu T [43]
  • Thader A [43]
  • Graham BS [42]
  • Mills DJ [42]
  • Zhang X [41]
  • Chen X [40]
  • Kollman JM [40]
  • Wang N [40]
  • Lyumkis D [39]
  • Zhang Y [39]
  • Fandrich M [38]
  • Glass B [38]
  • Mascola JR [38]
  • Ren J [38]
  • Schmidt M [38]
  • Turner HL [38]
  • Nogales E [37]
  • Zhou T [37]
  • Corbett KS [36]
  • Johnson MC [36]
  • Ricana CL [36]
  • Scheres SHW [36]
  • Vogt VM [36]
  • Doria-rose NA [35]
  • Langer J [35]
  • Murphy BJ [35]
  • Briggs JA [34]
  • Chen J [34]
  • Feathers JR [34]
  • Hagen WJ [34]
  • Kohler F [34]
  • Qu K [34]
  • Duyvesteyn HME [33]
  • Kirchdoerfer RN [33]
  • Shapiro L [33]
  • Torres JL [33]
  • Wilson IA [33]
  • Liu C [32]
  • Olia AS [32]
  • Potter CS [32]
  • Carragher B [31]
  • Chuang GY [31]
  • Feigl E [31]
  • Mattei S [31]
  • Rawi R [31]
  • Shen CH [31]
  • Wang S [31]
  • Diamond MS [29]
  • Faendrich M [29]
  • Grigorieff N [29]
  • Klusch N [29]
  • Yildiz O [29]
  • Zhou D [29]
  • Honemann MN [28]
  • Klanschnig M [28]
  • Li Z [28]
  • Mongkolsapaya J [28]
  • Nikulin N [28]
  • Screaton GR [28]
  • Yelshanskaya MV [28]
  • De Val N [28]
  • Liu Y [27]
  • Supasa P [27]
  • Tsybovsky Y [27]
  • Williamson JR [27]
  • Xiong X [27]
  • Clare DK [26]
  • Davis JH [26]
  • Dejnirattisai W [26]
  • Kotecha A [26]
  • Kube M [26]
  • Mentzer AJ [26]
  • Shi J [26]
  • Temperton N [26]
  • Wang J [26]
  • Yu H [26]
  • Chiu PL [25]
  • Moores CA [25]
  • Mueller AU [25]
  • Chen RE [24]
  • Funke JJ [24]

Author by ORCID

  • Briggs JAG [81]
  • Kwong PD [76]
  • Schur FKM [63]
  • Gorman J [53]
  • Mclellan JS [53]
  • Kuhlbrandt W [46]
  • Wrapp D [45]
  • Pallesen J [45]
  • Krausslich HG [44]
  • Darst SA [40]
  • Mills DJ [40]
  • Dietz H [37]
  • Scheres SHW [36]
  • Cottrell CA [36]
  • Ricana CL [36]
  • Murphy BJ [35]
  • Langer J [35]
  • Hagen WJ [34]
  • Kollman JM [34]
  • Briggs JA [34]
  • Qu K [33]
  • Torres JL [32]
  • Mattei S [31]
  • Ren J [30]
  • Grigorieff N [29]
  • Stuart DI [29]
  • Zhou D [29]
  • Klusch N [29]
  • Klanschnig M [28]
  • Kotecha A [26]
  • Mentzer AJ [26]
  • Xiong X [26]
  • Temperton N [26]
  • Davis JH [26]
  • Moores CA [25]
  • Chiu PL [25]
  • Wang N [25]
  • Mueller AU [25]
  • Nagel-yuksel B [24]
  • Willner EM [24]
  • Nguyen THD [23]
  • Zhou T [23]
  • Duyvesteyn HME [23]
  • Williamson JR [23]
  • Sobolevsky AI [22]
  • Li Z [22]
  • Nadezhdin KD [22]
  • Neuberger A [22]
  • Liu C [22]
  • Fry EE [21]
  • Nogales E [21]
  • Raunser S [20]
  • Ghanim GE [20]
  • Wang B [20]
  • Tan A [20]
  • Hall DR [20]
  • Howe A [20]
  • Paterson NG [20]
  • Stokes DL [19]
  • Vonck J [19]
  • Tan YZ [19]
  • Huiskonen JT [19]
  • Chen J [19]
  • Ciazynska KA [19]
  • Carter AP [18]
  • Nitz M [18]
  • Wong AHM [18]
  • Gilbert M [18]
  • Rini JM [18]
  • Chen X [18]
  • Yu H [18]
  • Boesen T [18]
  • Dick RA [18]
  • Jin M [18]
  • Walter TS [17]
  • Twomey EC [17]
  • Nissen P [17]
  • Korostelev AA [17]
  • Saibil HR [16]
  • Lu JM [16]
  • Cerutti G [16]
  • Wan W [16]
  • Molina N [16]
  • Ge J [15]
  • Campbell EA [15]
  • Goehring A [15]
  • Gouaux E [15]
  • Schmidt M [15]
  • Elferich J [15]
  • Yang H [15]
  • Meier-credo J [15]
  • Fandrich M [15]
  • Matsui A [15]
  • Chernikova D [15]
  • Hagen WJH [14]
  • Ward AB [14]
  • Loveland AB [14]
  • Brown A [14]
  • Grant T [14]
  • Ke Z [14]

Journal

  • NAT COMMUN [326]
  • PNAS [156]
  • NATURE [122]
  • TO BE PUBLISHED [120]
  • NAT STRUCT MOL BIOL [113]
  • SCIENCE [112]
  • ELIFE [95]
  • BIORXIV [88]
  • SCI ADV [87]
  • CELL [69]
  • STRUCTURE [56]
  • CELL REP [54]
  • COMMUN BIOL [46]
  • MOL CELL [46]
  • NUCLEIC ACIDS RES [36]
  • CELL HOST MICROBE [31]
  • SCI REP [27]
  • EMBO J [26]
  • J MOL BIOL [26]
  • PLOS PATHOG [24]
  • J BIOL CHEM [23]
  • J VIROL [18]
  • J STRUCT BIOL [16]
  • NAT MICROBIOL [13]
  • J EXP MED [11]
  • PROTEIN SCI [10]
  • CURR BIOL [9]
  • FRONT IMMUNOL [9]
  • ACTA CRYSTALLOGR D STRUCT BIOL [8]
  • CELL REP PHYS SCI [8]
  • NAT CHEM BIOL [8]
  • J CELL BIOL [7]
  • SCI TRANSL MED [7]
  • COMMUN CHEM [5]
  • IMMUNITY [5]
  • INT J MOL SCI [5]
  • NAT PLANTS [5]
  • RES SQ [5]
  • DEV CELL [4]
  • EMBO REP [4]
  • NAT MED [4]
  • NAT METHODS [4]
  • NAT NANOTECHNOL [4]
  • NEURON [4]
  • NPJ DRUG DISCOV [4]
  • SMALL [4]
  • ACS NANO [3]
  • BIOPHYS REV [3]
  • FEBS LETT [3]
  • MBIO [3]
  • METHODS [3]
  • NPJ BIOFILMS MICROBIOMES [3]
  • PROTEIN CELL [3]
  • BIOCHEM J [2]
  • BIOCHEMISTRY [2]
  • BIOMOLECULES [2]
  • BLOOD [2]
  • FRONT CELL INFECT MICROBIOL [2]
  • J.NEUROCHEM. [2]
  • MICROBIOL SPECTR [2]
  • NPJ VACCINES [2]
  • PLOS ONE [2]
  • SCI SIGNAL [2]
  • VIRUSES [2]
  • ACS CENT SCI [1]
  • ACS INFECT DIS. [1]
  • ACTA NEUROPATHOL [1]
  • ADV STRUCT CHEM IMAGING [1]
  • ANGEW CHEM INT ED ENGL [1]
  • AUTOPHAGY [1]
  • BBA ADV [1]
  • CANCER DISCOV [1]
  • CELL CHEM BIOL [1]
  • CELL DISCOV [1]
  • CELL REP MED [1]
  • COMPUT CRYST NEWSL [1]
  • EMERG MICROBES INFECT [1]
  • FRONT MICROBIOL [1]
  • FRONT MOL BIOSCI [1]
  • HUM MOL GENE [1]
  • J CELL SCI [1]
  • J GEN PHYSIOL [1]
  • J.INORG.BIOCHEM. [1]
  • JOULE [1]
  • MABS [1]
  • MOL BIOL CELL [1]
  • NAT CELL BIOL [1]
  • NAT CHEM [1]
  • NAT MATER [1]
  • PLOS BIOL [1]
  • PNAS NEXUS [1]
  • PROG BIOPHYS MOL BIOL [1]
  • RNA [1]
  • THERANOSTICS [1]

Software

  • RELION [779]
  • CRYOSPARC [619]
  • CTFFIND [175]
  • IMOD [103]
  • GCTF [100]
  • FREALIGN [81]
  • MATLAB [65]
  • AV3 [56]
  • CISTEM [46]
  • TOM TOOLBOX [44]
  • PHENIX [34]
  • DYNAMO [32]
  • APPION [24]
  • WARP [24]
  • CTFPHASEFLIP [21]
  • NOVACTF [21]
  • CTFTILT [19]
  • EMAN [17]
  • XMIPP [17]
  • SUBTOM [16]
  • TOMOALIGN [15]
  • TOM [14]
  • CTFFIND3 [10]
  • EMAN2 [10]
  • FREALIX [10]
  • SPHIRE [10]
  • AMIRA [9]
  • ETOMO [9]
  • SPIDER [9]
  • PEET [8]
  • AMIRAFPM [7]
  • UCSF CHIMERAX [7]
  • SPRING [6]
  • UCSF CHIMERA [6]
  • JSPR [5]
  • CTFFIND4 [4]
  • EMAN, IMAGIC, SPIDER [4]
  • XMIPP, FREALIGN [4]
  • COOT [3]
  • SPARX [3]
  • CHIMERA [2]
  • CRYOLO [2]
  • EMAN, IMAGIC, RELION [2]
  • EMAN2 SPARX [2]
  • GCTF/RELION [2]
  • IMAGIC [2]
  • RELION, CTFFIND3 [2]
  • TOM, AV3 [2]
  • BSOFT [1]
  • CHIMERA, COOT [1]
  • CHIMERA, MDFF [1]
  • CHIMERA, ROSETTA [1]
  • CHIMERA, VMD, MDFF [1]
  • DIREX [1]
  • E2HELIXBOXER.PY [1]
  • EMAN2, SPARX [1]
  • EMCLARITY [1]
  • FREALIGNX [1]
  • I-TASSER, CHIMERA, DIREX [1]
  • IMOD, AV3, TOM, DYNAMO [1]
  • MOTIONCORR2 [1]
  • RELION2.1 [1]
  • RSREF [1]
  • SCIPION [1]
  • SEGREFINETHREED [1]
  • XMIPP, AND, FREALIGN [1]

Microscope

  • FEI TITAN KRIOS [1332]
  • TFS KRIOS [173]
  • FEI TALOS ARCTICA [81]
  • FEI POLARA 300 [57]
  • TFS GLACIOS [57]
  • FEI TECNAI F20 [29]
  • FEI TITAN [20]
  • JEOL 3200FSC [13]
  • FEI TECNAI ARCTICA [12]
  • TFS TALOS [10]
  • TFS TALOS F200C [10]
  • FEI TECNAI 20 [8]
  • FEI TECNAI F30 [8]
  • JEOL CRYO ARM 300 [7]
  • JEOL 3200FS [5]
  • FEI TECNAI 12 [4]
  • JEOL 2010F [1]
  • JEOL 2200FSC [1]
  • JEOL 3000SFF [1]
  • TFS TUNDRA [1]

Electron Source

  • FIELD EMISSION GUN [1817]
  • LAB6 [8]
  • TUNGSTEN HAIRPIN [2]
  • OTHER [1]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [608]
  • GATAN K3 6K X 4K [405]
  • GATAN K3 BIOQUANTUM 6K X 4K [313]
  • GATAN K2 QUANTUM 4K X 4K [158]
  • FEI FALCON III 4K X 4K [132]
  • FEI FALCON IV 4K X 4K [100]
  • FEI FALCON II 4K X 4K [38]
  • GATAN ULTRASCAN 4000 4K X 4K [13]
  • FEI CETA 4K X 4K [12]
  • GATAN K2 BASE 4K X 4K [9]
  • GATAN K3 BIOCONTINUUM 6K X 4K [8]
  • DIRECT ELECTRON DE-20 5K X 3K [7]
  • GATAN MULTISCAN [5]
  • FEI EAGLE 2K X 2K [4]
  • GENERIC GATAN 4K X 4K [4]
  • TFS FALCON 4I 4K X 4K [4]
  • DIRECT ELECTRON DE-64 8K X 8K [3]
  • GATAN K2 4K X 4K [3]
  • DIRECT ELECTRON APOLLO 4K X 4K [2]
  • GENERIC TVIPS 4K X 4K [2]
  • OTHER [2]
  • TVIPS TEMCAM-F416 4K X 4K [2]
  • DECTRIS ELA 1K X 0.5K [1]
  • DIRECT ELECTRON DE-12 4K X 3K [1]
  • DIRECT ELECTRON DE-16 4K X 4K [1]
  • FEI FALCON I 4K X 4K [1]
  • TVIPS TEMCAM-F816 8K X 8K [1]

EMPIAR Experiment type

  • EMDB [3]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [3]

External links

  • UniProt [1327]
  • PDB [1257]
  • PDBe-Kb [1231]
  • AlphaFold DB [1037]
  • Pfam [997]
  • InterPro [966]
  • Gene Ontology [948]
  • ChEBI [794]
  • ChEMBL [731]
  • DrugBank [576]
  • Complex Portal [348]
  • EMPIAR [213]
  • CATH [39]
  • SCOP2 [37]
  • EMDB [3]