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sample_name:"Tetrameric complex of RyR1 with FKBP12.6"

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Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Cellular component [12]
  • Complex [6]
  • Ligand [3]
  • Protein [3]

Organism

  • Oryctolagus cuniculus [18]
  • Homo sapiens [3]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [15]

Model molecular weight

  • 2-5 MDa [3]

Release Date

  • 2026 [16]
  • 2025 [2]

Author by name

  • Molinarolo SM [18]
  • Van Petegem F [18]
  • Molinarolo S [13]
  • Valdivia CR [13]
  • Valdivia HH [13]

Author by ORCID

  • Van Petegem F [18]
  • Molinarolo S [13]
  • Molinarolo SM [5]

Journal

  • NAT COMMUN [13]
  • TO BE PUBLISHED [5]

Software

  • CRYOSPARC [18]

Microscope

  • TFS KRIOS [18]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • FEI FALCON IV 4K X 4K [18]

External links

  • PDB [18]
  • AlphaFold DB [3]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [3]
  • Gene Ontology [3]
  • InterPro [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • Complex Portal [1]
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Showing 1 - 10 of 18. Page 1 of 2
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EMD-70584
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3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Consensus Map
CryoEM
Consensus map
Release date: March 25, 2026
Resolution: 3.37 Å
EM Method: Single-particle

Molinarolo SM, Van Petegem F

To Be Published

EMD-70585
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation N-terminal Domain Locally Refined Map
CryoEM
Focused map
Release date: March 25, 2026
Resolution: 3.1 Å
EM Method: Single-particle

Molinarolo SM, Van Petegem F

To Be Published

EMD-70586
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation BSol Locally Refined Map
CryoEM
Focused map
Release date: March 25, 2026
Resolution: 3.35 Å
EM Method: Single-particle

Molinarolo SM, Van Petegem F

To Be Published

EMD-70587
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation C-terminal Domain Locally Refined Map
CryoEM
Focused map
Release date: March 25, 2026
Resolution: 3.04 Å
EM Method: Single-particle

Molinarolo SM, Van Petegem F

To Be Published

EMD-70588
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Transmembrane Domain C4 Locally Refined Map
CryoEM
Focused map
Release date: March 25, 2026
Resolution: 2.97 Å
EM Method: Single-particle

Molinarolo SM, Van Petegem F

To Be Published

EMD-70589
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: Drug Bound Open Conformation Composite Map
Composite map
CryoEM
Release date: Jan. 28, 2026
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 9ol4
Q-score: 0.462
Similar entry percentile: 53%

Molinarolo S, Valdivia CR, Valdivia HH, Van Petegem F

Nat Commun (2025) 16 pp. 11508-11508 [ DOI: doi:10.1038/s41467-025-66522-0 Pubmed: 41266329 ]

EMD-70574
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: DMSO Control Consensus Map
Consensus map
CryoEM
Release date: Jan. 21, 2026
Resolution: 3.11 Å
EM Method: Single-particle

Molinarolo S, Valdivia CR, Valdivia HH, Van Petegem F

Nat Commun (2025) 16 pp. 11508-11508 [ DOI: doi:10.1038/s41467-025-66522-0 Pubmed: 41266329 ]

EMD-70575
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: DMSO Control N-terminal Domain Locally Refined Map
Focused map
CryoEM
Release date: Jan. 21, 2026
Resolution: 2.86 Å
EM Method: Single-particle

Molinarolo S, Valdivia CR, Valdivia HH, Van Petegem F

Nat Commun (2025) 16 pp. 11508-11508 [ DOI: doi:10.1038/s41467-025-66522-0 Pubmed: 41266329 ]

EMD-70576
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: DMSO Control BSol Locally Refined Map
CryoEM
Focused map
Release date: Jan. 21, 2026
Resolution: 3.29 Å
EM Method: Single-particle

Molinarolo S, Valdivia CR, Valdivia HH, Van Petegem F

Nat Commun (2025) 16 pp. 11508-11508 [ DOI: doi:10.1038/s41467-025-66522-0 Pubmed: 41266329 ]

EMD-70577
Download Map
3D View
Cryo-EM Structure of Ryanodine Receptor 1: DMSO Control C-terminal Domain Locally Refined Map
Focused map
CryoEM
Release date: Jan. 21, 2026
Resolution: 3.09 Å
EM Method: Single-particle

Molinarolo S, Valdivia CR, Valdivia HH, Van Petegem F

Nat Commun (2025) 16 pp. 11508-11508 [ DOI: doi:10.1038/s41467-025-66522-0 Pubmed: 41266329 ]

Sort by: Download
Showing 1 - 10 of 18. Page 1 of 2
Display:
Statistics
×

Download


Preview 10 entries View All Download file

Filter By

Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Cellular component [12]
  • Complex [6]
  • Ligand [3]
  • Protein [3]

Organism

  • Oryctolagus cuniculus [18]
  • Homo sapiens [3]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [15]

Model molecular weight

  • 2-5 MDa [3]

Release Date

  • 2026 [16]
  • 2025 [2]

Author by name

  • Molinarolo SM [18]
  • Van Petegem F [18]
  • Molinarolo S [13]
  • Valdivia CR [13]
  • Valdivia HH [13]

Author by ORCID

  • Van Petegem F [18]
  • Molinarolo S [13]
  • Molinarolo SM [5]

Journal

  • NAT COMMUN [13]
  • TO BE PUBLISHED [5]

Software

  • CRYOSPARC [18]

Microscope

  • TFS KRIOS [18]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • FEI FALCON IV 4K X 4K [18]

External links

  • PDB [18]
  • AlphaFold DB [3]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [3]
  • Gene Ontology [3]
  • InterPro [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • Complex Portal [1]