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sample_name:"Target of Rapamycin Complex 2"

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Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Complex [25]
  • Protein [24]
  • Ligand [17]
  • Sample [1]

Organism

  • Homo sapiens [19]
  • Saccharomyces cerevisiae [6]
  • Saccharomyces cerevisiae [1]

EM Method

  • Single-particle [25]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [6]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]
  • ≥ 8Å and < 12Å [1]
  • ≥ 20Å and < 30Å [1]

Model molecular weight

  • 500-1000 kDa [10]
  • 1-2 MDa [10]

Release Date

  • 2026 [14]
  • 2023 [1]
  • 2021 [3]
  • 2020 [5]
  • 2018 [1]
  • 2017 [1]
  • 2015 [1]

Author by name

  • Berneiser K [8]
  • Hall MN [8]
  • Imseng S [8]
  • Maier T [8]
  • Mangia F [8]
  • Stuttfeld E [8]
  • Ahsan B [7]
  • Anandapadamanaban M [7]
  • Bourguet M [7]
  • Hay IM [7]
  • Loewith R [7]
  • Perisic O [7]
  • Williams RL [7]
  • Ban N [5]
  • Bergmann A [5]
  • Boehringer D [5]
  • Gabus C [5]
  • Scaiola A [5]
  • Shimobayashi M [5]
  • Tafur L [5]
  • Tettamanti MG [5]
  • Zou L [5]
  • Craigie LM [3]
  • Waelchli M [3]
  • Walchli M [3]
  • Chen M [2]
  • Chu N [2]
  • Cole PA [2]
  • Congreve S [2]
  • Ficarro SB [2]
  • Freund D [2]
  • Gaubitz C [2]
  • Gray NS [2]
  • Groendyke BJ [2]
  • Hancock M [2]
  • Hennink M [2]
  • Karuppasamy M [2]
  • Kondo KT [2]
  • Lee JM [2]
  • Lee MJ [2]
  • Linde-garelli KY [2]
  • Marto JA [2]
  • Matas K [2]
  • Miller BD [2]
  • Mondal D [2]
  • O Meara Tr [2]
  • Oliveira TM [2]
  • Palanski BA [2]
  • Prouteau M [2]
  • Rogala KB [2]
  • Sabatini DM [2]
  • Sali A [2]
  • Schaffitzel C [2]
  • Shi Y [2]
  • Taylor MS [2]
  • Valenstein ML [2]
  • Wranik M [2]
  • Xiang Y [2]
  • Xibinaku K [2]
  • Van Eeuwen T [2]
  • Aebersold R [1]
  • Agard D [1]
  • Chen J [1]
  • Chen X [1]
  • Cheng Y [1]
  • Eltschinger S [1]
  • Gleason CE [1]
  • Huang M [1]
  • Jin M [1]
  • Joubert LM [1]
  • Konstantinidou G [1]
  • Kusmider B [1]
  • Leitner A [1]
  • Li C [1]
  • Li J [1]
  • Liu M [1]
  • Liu X [1]
  • Nowotny C [1]
  • Pearce D [1]
  • Qi Y [1]
  • Rispal D [1]
  • Robinson GC [1]
  • Saha B [1]
  • Tafir L [1]
  • Takagi E [1]
  • Thore S [1]
  • Tian Y [1]
  • Wang F [1]
  • Wang H [1]
  • Wang HW [1]
  • Wang J [1]
  • Wong CCL [1]
  • Wu Z [1]
  • Xu Y [1]
  • Yang H [1]
  • Yu Z [1]
  • Zhao D [1]

Author by ORCID

  • Mangia F [8]
  • Berneiser K [8]
  • Hall MN [8]
  • Maier T [8]
  • Boehringer D [5]
  • Shimobayashi M [5]
  • Ban N [5]
  • Scaiola A [5]
  • Walchli M [3]
  • Imseng S [3]
  • Stuttfeld E [3]
  • Craigie LM [3]
  • Gray NS [2]
  • Taylor MS [2]
  • Rogala KB [2]
  • Cole PA [2]
  • Valenstein ML [2]
  • Chu N [2]
  • Sabatini DM [2]
  • Ficarro SB [2]
  • Chen M [2]
  • Shi Y [2]
  • O'meara TR [2]
  • Palanski BA [2]
  • Mondal D [2]
  • Gaubitz C [2]
  • Xiang Y [2]
  • Sali A [2]
  • Van Eeuwen T [2]
  • Marto JA [2]
  • Oliveira TM [2]
  • Linde-garelli KY [2]
  • Hennink M [2]
  • Xibinaku K [2]
  • Congreve S [2]
  • Kondo KT [2]
  • Matas K [2]
  • Miller BD [2]
  • Freund D [2]
  • Lee MJ [2]
  • Thore S [1]
  • Wong CCL [1]
  • Yu Z [1]
  • Konstantinidou G [1]
  • Wang F [1]
  • Schaffitzel C [1]
  • Loewith R [1]
  • Takagi E [1]
  • Liu M [1]
  • Robinson GC [1]
  • Joubert LM [1]
  • Chen J [1]
  • Agard D [1]
  • Leitner A [1]
  • Jin M [1]
  • Kusmider B [1]

Journal

  • BIORXIV [7]
  • MOL CELL [7]
  • SCI ADV [5]
  • ELIFE [3]
  • SCIENCE [2]
  • CELL RES [1]
  • J BIOL CHEM [1]
  • NAT COMMUN [1]

Software

  • RELION [12]
  • CRYOSPARC [10]
  • CRYOLO [1]
  • XMIPP, RELION [1]

Microscope

  • TFS KRIOS [14]
  • FEI TITAN KRIOS [11]
  • FEI/PHILIPS CM120T [1]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [7]
  • TFS FALCON 4I 4K X 4K [7]
  • FEI FALCON IV 4K X 4K [5]
  • GATAN K3 6K X 4K [2]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]
  • FEI FALCON II 4K X 4K [1]
  • FEI FALCON III 4K X 4K [1]
  • GATAN K2 QUANTUM 4K X 4K [1]
  • TVIPS TEMCAM-F415 4K X 4K [1]

External links

  • PDB [26]
  • AlphaFold DB [23]
  • Complex Portal [23]
  • PDBe-Kb [23]
  • UniProt [23]
  • ChEBI [17]
  • ChEMBL [17]
  • DrugBank [17]
  • Gene Ontology [17]
  • Pfam [17]
  • InterPro [8]
  • SCOP2 [1]
Sort by: Download
Showing 1 - 10 of 26. Page 1 of 3
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Preview first 10
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EMD-54222
Download Map
3D View
Cryo-EM structure of the Target of Rapamycin Complex 2 TORC2 with the Avo1 PH domain monomer
Consensus map
CryoEM
Release date: May 6, 2026
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 9rsq
Q-score: 0.345

Zou L, Tettamanti MG, Gabus C, Bergmann A, Loewith R, Tafur L

Mol Cell (2026) 86 pp. 1560-1573.e5 [ DOI: doi:10.1016/j.molcel.2026.03.022 Pubmed: 41997113 ]

EMD-54223
Download Map
3D View
Cryo-EM structure of the Target of Rapamycin Complex 2 TORC2 with the Avo1 PH domain
CryoEM
Release date: May 6, 2026
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9rss
Q-score: 0.338

Zou L, Tettamanti MG, Gabus C, Bergmann A, Loewith R, Tafur L

Mol Cell (2026) 86 pp. 1560-1573.e5 [ DOI: doi:10.1016/j.molcel.2026.03.022 Pubmed: 41997113 ]

EMD-54224
Download Map
3D View
Cryo-EM structure of the Target of Rapamycin Complex 2 TORC2 in autoinhibted conformation monomer
CryoEM
Consensus map
Release date: May 6, 2026
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 9rst
Q-score: 0.343

Zou L, Tettamanti MG, Gabus C, Bergmann A, Loewith R, Tafur L

Mol Cell (2026) 86 pp. 1560-1573.e5 [ DOI: doi:10.1016/j.molcel.2026.03.022 Pubmed: 41997113 ]

EMD-54227
Download Map
3D View
Cryo-EM structure of the Target of Rapamycin Complex 2 TORC2 consensus refinement
CryoEM
Release date: May 6, 2026
Resolution: 2.4 Å
EM Method: Single-particle

Zou L, Tettamanti MG, Gabus C, Bergmann A, Loewith R, Tafur L

Mol Cell (2026) 86 pp. 1560-1573.e5 [ DOI: doi:10.1016/j.molcel.2026.03.022 Pubmed: 41997113 ]

EMD-54228
Download Map
3D View
Cryo-EM structure of the Target of Rapamycin Complex 2 TORC2 monomer focused
CryoEM
Release date: May 6, 2026
Resolution: 2.32 Å
EM Method: Single-particle

Zou L, Tettamanti MG, Gabus C, Bergmann A, Loewith R, Tafur L

Mol Cell (2026) 86 pp. 1560-1573.e5 [ DOI: doi:10.1016/j.molcel.2026.03.022 Pubmed: 41997113 ]

EMD-55637
Download Map
3D View
cryo-EM structure of AKT phosphorylated mTOR complex 2, overall refinement
Composite map
CryoEM
Release date: April 22, 2026
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9t7j
Q-score: 0.524

Hay IM, Bourguet M, Ahsan B, Perisic O, Anandapadamanaban M, Williams RL

bioRxiv (2026) [ DOI: doi:10.64898/2026.01.08.698367 ]

EMD-55714
Download Map
3D View
cryo-EM structure of autophosphorylated mTOR complex 2, overall refinement
Composite map
CryoEM
Release date: April 22, 2026
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9t92
Q-score: 0.486

Hay IM, Bourguet M, Ahsan B, Perisic O, Anandapadamanaban M, Williams RL

bioRxiv (2026) [ DOI: doi:10.64898/2026.01.08.698367 ]

EMD-55715
Download Map
3D View
cryo-EM structure of autophosphorylated mTOR complex 2, focused on a single protomer
CryoEM
Release date: April 22, 2026
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 9t93
Q-score: 0.562

Hay IM, Bourguet M, Ahsan B, Perisic O, Anandapadamanaban M, Williams RL

bioRxiv (2026) [ DOI: doi:10.64898/2026.01.08.698367 ]

EMD-55716
Download Map
3D View
cryo-EM structure of AKT phosphorylated mTOR complex 2, focused on a single protomer
CryoEM
Release date: April 22, 2026
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9t94
Q-score: 0.589

Hay IM, Bourguet M, Ahsan B, Perisic O, Anandapadamanaban M, Williams RL

bioRxiv (2026) [ DOI: doi:10.64898/2026.01.08.698367 ]

EMD-55803
Download Map
3D View
cryo-EM structure of dephosphorylated mTOR complex 2, overall refinement
Composite map
CryoEM
Release date: April 22, 2026
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9tds
Q-score: 0.475

Hay IM, Bourguet M, Ahsan B, Perisic O, Anandapadamanaban M, Williams RL

bioRxiv (2026) [ DOI: doi:10.64898/2026.01.08.698367 ]

Sort by: Download
Showing 1 - 10 of 26. Page 1 of 3
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [26]

Current status

  • REL [26]

Sample type

  • Complex [25]
  • Protein [24]
  • Ligand [17]
  • Sample [1]

Organism

  • Homo sapiens [19]
  • Saccharomyces cerevisiae [6]
  • Saccharomyces cerevisiae [1]

EM Method

  • Single-particle [25]
  • Subtomogram averaging [1]

Resolution

  • ≥ 2Å and < 3Å [6]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]
  • ≥ 8Å and < 12Å [1]
  • ≥ 20Å and < 30Å [1]

Model molecular weight

  • 500-1000 kDa [10]
  • 1-2 MDa [10]

Release Date

  • 2026 [14]
  • 2023 [1]
  • 2021 [3]
  • 2020 [5]
  • 2018 [1]
  • 2017 [1]
  • 2015 [1]

Author by name

  • Berneiser K [8]
  • Hall MN [8]
  • Imseng S [8]
  • Maier T [8]
  • Mangia F [8]
  • Stuttfeld E [8]
  • Ahsan B [7]
  • Anandapadamanaban M [7]
  • Bourguet M [7]
  • Hay IM [7]
  • Loewith R [7]
  • Perisic O [7]
  • Williams RL [7]
  • Ban N [5]
  • Bergmann A [5]
  • Boehringer D [5]
  • Gabus C [5]
  • Scaiola A [5]
  • Shimobayashi M [5]
  • Tafur L [5]
  • Tettamanti MG [5]
  • Zou L [5]
  • Craigie LM [3]
  • Waelchli M [3]
  • Walchli M [3]
  • Chen M [2]
  • Chu N [2]
  • Cole PA [2]
  • Congreve S [2]
  • Ficarro SB [2]
  • Freund D [2]
  • Gaubitz C [2]
  • Gray NS [2]
  • Groendyke BJ [2]
  • Hancock M [2]
  • Hennink M [2]
  • Karuppasamy M [2]
  • Kondo KT [2]
  • Lee JM [2]
  • Lee MJ [2]
  • Linde-garelli KY [2]
  • Marto JA [2]
  • Matas K [2]
  • Miller BD [2]
  • Mondal D [2]
  • O Meara Tr [2]
  • Oliveira TM [2]
  • Palanski BA [2]
  • Prouteau M [2]
  • Rogala KB [2]
  • Sabatini DM [2]
  • Sali A [2]
  • Schaffitzel C [2]
  • Shi Y [2]
  • Taylor MS [2]
  • Valenstein ML [2]
  • Wranik M [2]
  • Xiang Y [2]
  • Xibinaku K [2]
  • Van Eeuwen T [2]
  • Aebersold R [1]
  • Agard D [1]
  • Chen J [1]
  • Chen X [1]
  • Cheng Y [1]
  • Eltschinger S [1]
  • Gleason CE [1]
  • Huang M [1]
  • Jin M [1]
  • Joubert LM [1]
  • Konstantinidou G [1]
  • Kusmider B [1]
  • Leitner A [1]
  • Li C [1]
  • Li J [1]
  • Liu M [1]
  • Liu X [1]
  • Nowotny C [1]
  • Pearce D [1]
  • Qi Y [1]
  • Rispal D [1]
  • Robinson GC [1]
  • Saha B [1]
  • Tafir L [1]
  • Takagi E [1]
  • Thore S [1]
  • Tian Y [1]
  • Wang F [1]
  • Wang H [1]
  • Wang HW [1]
  • Wang J [1]
  • Wong CCL [1]
  • Wu Z [1]
  • Xu Y [1]
  • Yang H [1]
  • Yu Z [1]
  • Zhao D [1]

Author by ORCID

  • Mangia F [8]
  • Berneiser K [8]
  • Hall MN [8]
  • Maier T [8]
  • Boehringer D [5]
  • Shimobayashi M [5]
  • Ban N [5]
  • Scaiola A [5]
  • Walchli M [3]
  • Imseng S [3]
  • Stuttfeld E [3]
  • Craigie LM [3]
  • Gray NS [2]
  • Taylor MS [2]
  • Rogala KB [2]
  • Cole PA [2]
  • Valenstein ML [2]
  • Chu N [2]
  • Sabatini DM [2]
  • Ficarro SB [2]
  • Chen M [2]
  • Shi Y [2]
  • O'meara TR [2]
  • Palanski BA [2]
  • Mondal D [2]
  • Gaubitz C [2]
  • Xiang Y [2]
  • Sali A [2]
  • Van Eeuwen T [2]
  • Marto JA [2]
  • Oliveira TM [2]
  • Linde-garelli KY [2]
  • Hennink M [2]
  • Xibinaku K [2]
  • Congreve S [2]
  • Kondo KT [2]
  • Matas K [2]
  • Miller BD [2]
  • Freund D [2]
  • Lee MJ [2]
  • Thore S [1]
  • Wong CCL [1]
  • Yu Z [1]
  • Konstantinidou G [1]
  • Wang F [1]
  • Schaffitzel C [1]
  • Loewith R [1]
  • Takagi E [1]
  • Liu M [1]
  • Robinson GC [1]
  • Joubert LM [1]
  • Chen J [1]
  • Agard D [1]
  • Leitner A [1]
  • Jin M [1]
  • Kusmider B [1]

Journal

  • BIORXIV [7]
  • MOL CELL [7]
  • SCI ADV [5]
  • ELIFE [3]
  • SCIENCE [2]
  • CELL RES [1]
  • J BIOL CHEM [1]
  • NAT COMMUN [1]

Software

  • RELION [12]
  • CRYOSPARC [10]
  • CRYOLO [1]
  • XMIPP, RELION [1]

Microscope

  • TFS KRIOS [14]
  • FEI TITAN KRIOS [11]
  • FEI/PHILIPS CM120T [1]

Electron Source

  • FIELD EMISSION GUN [26]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [7]
  • TFS FALCON 4I 4K X 4K [7]
  • FEI FALCON IV 4K X 4K [5]
  • GATAN K3 6K X 4K [2]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]
  • FEI FALCON II 4K X 4K [1]
  • FEI FALCON III 4K X 4K [1]
  • GATAN K2 QUANTUM 4K X 4K [1]
  • TVIPS TEMCAM-F415 4K X 4K [1]

External links

  • PDB [26]
  • AlphaFold DB [23]
  • Complex Portal [23]
  • PDBe-Kb [23]
  • UniProt [23]
  • ChEBI [17]
  • ChEMBL [17]
  • DrugBank [17]
  • Gene Ontology [17]
  • Pfam [17]
  • InterPro [8]
  • SCOP2 [1]