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sample_name:"Structure of an antagonist-bound MRGPRX4-Gq complex"

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Author by name

  • Cao C [2]
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  • Liu Y [2]
  • Shen R [2]
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Author by ORCID

  • Lei X [2]
  • Fan J [2]
  • Yang J [2]
  • Li Y [2]
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  • NAT CHEM BIOL [2]

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  • CRYOSPARC [2]

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  • GATAN K3 6K X 4K [2]

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EMD-64829
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cryoEM structure of HEP-50768-bound MRGPRX4-Gq complex
CryoEM
Release date: May 6, 2026
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 9v81
Q-score: 0.592

Yang J, Shen R, Wang C, Zhu W, Ke H, Fan J, Zhang M, Liu Y, Li S, Li G, Wang X, Li Y, Cao C, Lei X

Nat Chem Biol (2026) [ DOI: doi:10.1038/s41589-026-02195-0 Pubmed: 41957282 ]

EMD-64830
Download Map
3D View
Local refine map of HEP-50768-bound MRGPRX4
CryoEM
Release date: May 6, 2026
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 9v82
Q-score: 0.599

Yang J, Shen R, Wang C, Zhu W, Ke H, Fan J, Zhang M, Liu Y, Li S, Li G, Wang X, Li Y, Cao C, Lei X

Nat Chem Biol (2026) [ DOI: doi:10.1038/s41589-026-02195-0 Pubmed: 41957282 ]

Sort by: Download
Showing 1 - 2 of 2. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [2]

Current status

  • REL [2]

Sample type

  • Complex [2]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [2]
  • Mus musculus [1]

EM Method

  • Single-particle [2]

Resolution

  • ≥ 2Å and < 3Å [2]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [1]

Release Date

  • 2026 [2]

Author by name

  • Cao C [2]
  • Fan J [2]
  • Ke H [2]
  • Lei X [2]
  • Li G [2]
  • Li S [2]
  • Li Y [2]
  • Liu Y [2]
  • Shen R [2]
  • Wang C [2]
  • Wang X [2]
  • Yang J [2]
  • Zhang M [2]
  • Zhu W [2]

Author by ORCID

  • Lei X [2]
  • Fan J [2]
  • Yang J [2]
  • Li Y [2]
  • Cao C [2]

Journal

  • NAT CHEM BIOL [2]

Software

  • CRYOSPARC [2]

Microscope

  • TFS KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [2]

Film or detector model

  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]
  • Complex Portal [1]