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sample_name:"Heteromeric GluA1A2 with positive allosteric modulator (R,R)-2b and agonist glutamate (Glu)"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [2]
  • Ligand [1]

Organism

  • Rattus norvegicus [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 250-500 kDa [1]

Release Date

  • 2026 [5]

Author by name

  • Aktolun M [5]
  • Clausen RP [5]
  • Gangwar SP [5]
  • Kurnikova MG [5]
  • Newton TP [5]
  • Sobolevsky AI [5]
  • Yelshanskaya MV [5]
  • Yen LY [5]

Author by ORCID

  • Sobolevsky AI [5]
  • Newton TP [5]
  • Aktolun M [5]
  • Kurnikova MG [5]
  • Gangwar SP [5]

Journal

  • NAT COMMUN [5]

Software

  • CRYOSPARC [4]

Microscope

  • TFS KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [5]

External links

  • AlphaFold DB [2]
  • Complex Portal [2]
  • PDBe-Kb [2]
  • UniProt [2]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
  • PDB [1]
  • Pfam [1]
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EMD-70913
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3D View
Heteromeric GluA1/A2 in the activated state, consensus refinement of ATD-LBD-TMD
CryoEM
Consensus map
Release date: April 8, 2026
Resolution: 3.3 Å
EM Method: Single-particle

Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI

Nat Commun (2026) [ Pubmed: 41904128 DOI: doi:10.1038/s41467-026-71063-1 ]

EMD-70914
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3D View
Heteromeric GluA1/A2 in the activated state, ligand binding domain LBD
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 3.13 Å
EM Method: Single-particle

Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI

Nat Commun (2026) [ Pubmed: 41904128 DOI: doi:10.1038/s41467-026-71063-1 ]

EMD-70915
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3D View
Heteromeric GluA1/A2 in the activated state, transmembrane domain TMD
CryoEM
Focused map
Release date: April 8, 2026
Resolution: 3.81 Å
EM Method: Single-particle

Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI

Nat Commun (2026) [ Pubmed: 41904128 DOI: doi:10.1038/s41467-026-71063-1 ]

EMD-70919
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3D View
Composite map of GluA1/A2 in the activated state, in complex with positive allosteric modulator R,R -2b and agonist glutamate ATD-LBD-TMD
Composite map
CryoEM
Release date: April 8, 2026
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9ovu
Q-score: 0.387

Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI

Nat Commun (2026) [ Pubmed: 41904128 DOI: doi:10.1038/s41467-026-71063-1 ]

EMD-75274
Download Map
3D View
Heteromeric GluA1/A2 in the activated state, amino-terminal domain ATD
CryoEM
Focused map
Release date: April 8, 2026
Resolution: 3.94 Å
EM Method: Single-particle

Yen LY, Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Clausen RP, Kurnikova MG, Sobolevsky AI

Nat Commun (2026) [ Pubmed: 41904128 DOI: doi:10.1038/s41467-026-71063-1 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [2]
  • Ligand [1]

Organism

  • Rattus norvegicus [5]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 250-500 kDa [1]

Release Date

  • 2026 [5]

Author by name

  • Aktolun M [5]
  • Clausen RP [5]
  • Gangwar SP [5]
  • Kurnikova MG [5]
  • Newton TP [5]
  • Sobolevsky AI [5]
  • Yelshanskaya MV [5]
  • Yen LY [5]

Author by ORCID

  • Sobolevsky AI [5]
  • Newton TP [5]
  • Aktolun M [5]
  • Kurnikova MG [5]
  • Gangwar SP [5]

Journal

  • NAT COMMUN [5]

Software

  • CRYOSPARC [4]

Microscope

  • TFS KRIOS [5]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [5]

External links

  • AlphaFold DB [2]
  • Complex Portal [2]
  • PDBe-Kb [2]
  • UniProt [2]
  • ChEBI [1]
  • ChEMBL [1]
  • DrugBank [1]
  • PDB [1]
  • Pfam [1]