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sample_name:"Complex of FBXO42-CCDC6-PP2Ac"

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Current Database

  • EMDB [20]

Current status

  • REL [20]

Sample type

  • Complex [20]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [20]

EM Method

  • Single-particle [20]

Resolution

  • ≥ 3Å and < 4Å [14]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [1]

Release Date

  • 2026 [20]

Author by name

  • Azumaya C [20]
  • Coassolo S [20]
  • Hsu PL [20]
  • Maculins T [20]
  • Michaelian N [20]
  • Yauch RL [20]
  • Dimitrova Y [19]
  • Azumaya CM [1]
  • Cheung TK [1]
  • Costa M [1]
  • Dimitrova YN [1]
  • Fortin JP [1]
  • Garner T [1]
  • Grimmer M [1]
  • Lau T [1]
  • Mau D [1]
  • Pahuja KB [1]
  • Rose CM [1]
  • Yin J [1]
  • Zilberleyb I [1]

Author by ORCID

  • Yauch RL [1]
  • Azumaya CM [1]
  • Maculins T [1]
  • Hsu PL [1]
  • Michaelian N [1]
  • Mau D [1]

Journal

  • TO BE PUBLISHED [19]
  • NATURE [1]

Software

  • CRYOSPARC [20]

Microscope

  • TFS KRIOS [20]

Electron Source

  • FIELD EMISSION GUN [20]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [20]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]
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Showing 1 - 10 of 20. Page 1 of 2
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EMD-49984
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3D View
Consensus refinement of the FBXO42-CCDC6-PP2Ac degradasome
CryoEM
Release date: April 29, 2026
Resolution: 3.9 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49991
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3D View
Focused refinement of PP2Ac repeat 1 of the FBXO42-CCDC6-PP2Ac degradasome
CryoEM
Release date: April 29, 2026
Resolution: 4.0 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49985
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3D View
Focused refinement of PP2Ac repeats 3 and 4 of the CCDC6-PP2Ac complex
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 4.5 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49986
Download Map
3D View
Focused refinement of PP2Ac repeat 4 of the CCDC6-PP2Ac complex
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 6.5 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49987
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3D View
Focused refinement of PP2Ac repeats 2 and 3 of the CCDC6-PP2Ac complex
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 3.9 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49988
Download Map
3D View
Focused refinement of PP2Ac repeat 3 of the CCDC6-PP2Ac complex
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 4.1 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49989
Download Map
3D View
Focused refinement of PP2Ac repeats 1 and 2 of the CCDC6-PP2Ac complex
CryoEM
Focused map
Release date: April 8, 2026
Resolution: 3.9 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49990
Download Map
3D View
Focused refinement of PP2Ac repeat 2 of the CCDC6-PP2Ac complex
Focused map
CryoEM
Release date: April 8, 2026
Resolution: 3.7 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

EMD-49966
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CryoEM structure of the FBXO42-CCDC6-PP2Ac degradasome
Composite map
CryoEM
Release date: Jan. 21, 2026
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9o04
Q-score: 0.396

Coassolo S, Michaelian N, Maculins T, Azumaya CM, Cheung TK, Yin J, Zilberleyb I, Pahuja KB, Garner T, Lau T, Mau D, Grimmer M, Fortin JP, Costa M, Dimitrova YN, Rose CM, Hsu PL, Yauch RL

Nature (2026) [ Pubmed: 41986709 DOI: doi:10.1038/s41586-026-10368-z ]

EMD-49974
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3D View
Focused refinement of FBXO42-CCDC6-PP2Ac degradasome PP2Ac repeat4
Focused map
CryoEM
Release date: Jan. 21, 2026
Resolution: 6.6 Å
EM Method: Single-particle

Hsu PL, Michaelian N, Azumaya C, Coassolo S, Yauch RL, Maculins T, Dimitrova Y

To Be Published

Sort by: Download
Showing 1 - 10 of 20. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [20]

Current status

  • REL [20]

Sample type

  • Complex [20]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [20]

EM Method

  • Single-particle [20]

Resolution

  • ≥ 3Å and < 4Å [14]
  • ≥ 4Å and < 5Å [3]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [2]

Model molecular weight

  • 250-500 kDa [1]
  • 500-1000 kDa [1]

Release Date

  • 2026 [20]

Author by name

  • Azumaya C [20]
  • Coassolo S [20]
  • Hsu PL [20]
  • Maculins T [20]
  • Michaelian N [20]
  • Yauch RL [20]
  • Dimitrova Y [19]
  • Azumaya CM [1]
  • Cheung TK [1]
  • Costa M [1]
  • Dimitrova YN [1]
  • Fortin JP [1]
  • Garner T [1]
  • Grimmer M [1]
  • Lau T [1]
  • Mau D [1]
  • Pahuja KB [1]
  • Rose CM [1]
  • Yin J [1]
  • Zilberleyb I [1]

Author by ORCID

  • Yauch RL [1]
  • Azumaya CM [1]
  • Maculins T [1]
  • Hsu PL [1]
  • Michaelian N [1]
  • Mau D [1]

Journal

  • TO BE PUBLISHED [19]
  • NATURE [1]

Software

  • CRYOSPARC [20]

Microscope

  • TFS KRIOS [20]

Electron Source

  • FIELD EMISSION GUN [20]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [20]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]