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primary_citation_author:"Bruni R"

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Current Database

  • EMDB [6]
  • EMPIAR [4]

Current status

  • REL [10]

Sample type

  • Protein [6]
  • Ligand [5]
  • Cellular component [4]
  • Complex [2]

Organism

  • Drosophila melanogaster [5]
  • Homo sapiens [1]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [2]
  • 250-500 kDa [3]

Release Date

  • 2025 [10]

Author by name

  • Cerutti G [9]
  • Bruni R [6]
  • Ahlsen G [5]
  • Arias R [5]
  • Bahna F [5]
  • Katsamba PS [5]
  • Kloss B [5]
  • Mannepalli S [5]
  • Shapiro L [5]
  • Tomlinson A [5]
  • Accardi A [1]
  • Alvarenga OE [1]
  • Chakraborty S [1]
  • Feng Z [1]
  • Gupta K [1]
  • Khelashvili G [1]
  • Lee S [1]
  • Panda A [1]
  • Zhang S [1]

Author by ORCID

  • Tomlinson A [5]
  • Cerutti G [5]
  • Katsamba PS [5]
  • Lee S [1]
  • Khelashvili G [1]
  • Chakraborty S [1]
  • Gupta K [1]
  • Feng Z [1]
  • Accardi A [1]

Journal

  • MOL CELL [9]
  • NAT COMMUN [1]

Microscope

  • FEI TITAN KRIOS [5]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [5]
  • GATAN K3 6K X 4K [1]

EMPIAR Experiment type

  • EMDB [4]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [4]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • UniProt [6]
  • ChEBI [5]
  • ChEMBL [5]
  • EMPIAR [5]
  • InterPro [5]
  • Pfam [5]
  • EMDB [4]
  • Complex Portal [1]
  • Gene Ontology [1]
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EMPIAR-12321
Related EMDB
EMD-44508 EMD-44507 EMD-44509
Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 4.6)
Release date: June 2, 2025
Dataset size: 1.5 TB
Experiment type: EMDB

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: 10.1016/j.molcel.2024.10.017 ]

Image sets:
  • Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 4.6)
EMPIAR-12169
Related EMDB
EMD-44502
Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 8)
Release date: May 30, 2025
Dataset size: 2.8 TB
Experiment type: EMDB

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: 10.1016/j.molcel.2024.10.017 ]

Image sets:
  • Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 8)
EMD-44744
Download Map
3D View
Structure of human Xk-related protein 4
CryoEM
Release date: May 14, 2025
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9boj
Q-score: 0.437

Chakraborty S, Feng Z, Lee S, Alvarenga OE, Panda A, Zhang S, Bruni R, Khelashvili G, Gupta K, Accardi A

Nat Commun (2025) 16 pp. 7317-7317 [ DOI: doi:10.1038/s41467-025-62739-1 Pubmed: 40781244 ]

EMPIAR-12320
Related EMDB
EMD-44503 EMD-44504
Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain in complex with Bride of Sevenless extracellular domain (pH 6.6)
Release date: April 7, 2025
Dataset size: 3.0 TB
Experiment type: EMDB

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: 10.1016/j.molcel.2024.10.017 ]

Image sets:
  • Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain in complex with Bride of Sevenless extracellular domain (pH 6.6)
EMPIAR-12304
Related EMDB
EMD-44505
Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 6.6)
Release date: March 21, 2025
Dataset size: 1.3 TB
Experiment type: EMDB

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: 10.1016/j.molcel.2024.10.017 ]

Image sets:
  • Single-particle cryo-EM unaligned micrographs of Sevenless extracellular domain (pH 8)
EMD-44502
Download Map
3D View
Raw data
EMPIAR-12169
Cryo-EM structure of Sevenless extracellular domain monomer
CryoEM
Release date: Jan. 29, 2025
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 9bfp
Q-score: 0.532

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: doi:10.1016/j.molcel.2024.10.017 ]

EMD-44503
Download Map
3D View
Raw data
EMPIAR-12320
Cryo-EM structure of Sevenless in complex with Bride of Sevenless
CryoEM
Release date: Jan. 29, 2025
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9bfq
Q-score: 0.496

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: doi:10.1016/j.molcel.2024.10.017 ]

EMD-44504
Download Map
3D View
Raw data
EMPIAR-12320
Cryo-EM structure of Bride of Sevenless extracellular domain dimer, Sevenless-bound form
CryoEM
Release date: Jan. 29, 2025
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 9bfr
Q-score: 0.451

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: doi:10.1016/j.molcel.2024.10.017 ]

EMD-44505
Download Map
3D View
Raw data
EMPIAR-12304
Cryo-EM structure of Sevenless extracellular domain dimer, pH 6.6
CryoEM
Release date: Jan. 29, 2025
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 9bfs
Q-score: 0.456

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: doi:10.1016/j.molcel.2024.10.017 ]

EMD-44507
Download Map
3D View
Raw data
EMPIAR-12321
Cryo-EM structure of Sevenless extracellular domain composite map of the dimer, pH 4.6
Composite map
CryoEM
Release date: Jan. 29, 2025
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 9bfu

Cerutti G, Arias R, Bahna F, Mannepalli S, Katsamba PS, Ahlsen G, Kloss B, Bruni R, Tomlinson A, Shapiro L

Mol Cell (2024) 84 pp. 4677-4690.e6 [ Pubmed: 39510067 DOI: doi:10.1016/j.molcel.2024.10.017 ]

Sort by: Download
Showing 1 - 10 of 10. Page 1 of 1
Display:
Statistics
×

Download












































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]
  • EMPIAR [4]

Current status

  • REL [10]

Sample type

  • Protein [6]
  • Ligand [5]
  • Cellular component [4]
  • Complex [2]

Organism

  • Drosophila melanogaster [5]
  • Homo sapiens [1]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [1]
  • ≥ 3Å and < 4Å [4]
  • ≥ 4Å and < 5Å [1]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [2]
  • 250-500 kDa [3]

Release Date

  • 2025 [10]

Author by name

  • Cerutti G [9]
  • Bruni R [6]
  • Ahlsen G [5]
  • Arias R [5]
  • Bahna F [5]
  • Katsamba PS [5]
  • Kloss B [5]
  • Mannepalli S [5]
  • Shapiro L [5]
  • Tomlinson A [5]
  • Accardi A [1]
  • Alvarenga OE [1]
  • Chakraborty S [1]
  • Feng Z [1]
  • Gupta K [1]
  • Khelashvili G [1]
  • Lee S [1]
  • Panda A [1]
  • Zhang S [1]

Author by ORCID

  • Tomlinson A [5]
  • Cerutti G [5]
  • Katsamba PS [5]
  • Lee S [1]
  • Khelashvili G [1]
  • Chakraborty S [1]
  • Gupta K [1]
  • Feng Z [1]
  • Accardi A [1]

Journal

  • MOL CELL [9]
  • NAT COMMUN [1]

Microscope

  • FEI TITAN KRIOS [5]
  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [5]
  • GATAN K3 6K X 4K [1]

EMPIAR Experiment type

  • EMDB [4]

EMPIAR Image category

  • MICROGRAPHS - MULTIFRAME [4]

External links

  • AlphaFold DB [6]
  • PDB [6]
  • PDBe-Kb [6]
  • UniProt [6]
  • ChEBI [5]
  • ChEMBL [5]
  • EMPIAR [5]
  • InterPro [5]
  • Pfam [5]
  • EMDB [4]
  • Complex Portal [1]
  • Gene Ontology [1]