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natural_source_ncbi_code:"652961"

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Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [10]
  • RNA [7]

Organism

  • Crimean-congo hemorrhagic fever orthonairovirus [18]
  • Homo sapiens [5]
  • Mus musculus [2]
  • Orthonairovirus haemorrhagiae [2]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [6]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [2]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [3]
  • 250-500 kDa [10]

Release Date

  • 2026 [9]
  • 2024 [8]
  • 2022 [1]

Author by name

  • Chang T [7]
  • Gui J [7]
  • Li J [7]
  • Pan H [7]
  • Xiong X [7]
  • Xue L [7]
  • Bakken RR [5]
  • Chandran K [5]
  • Herbert AS [5]
  • Kuehne AI [5]
  • Mclellan JS [5]
  • Monticelli SR [5]
  • Wang A [5]
  • Abelson D [4]
  • Balinandi S [4]
  • Barajas J [4]
  • Berrigan J [4]
  • Cao S [4]
  • Champney E [4]
  • Chong T [4]
  • Doyle M [4]
  • Dye JM [4]
  • Fu Y [4]
  • Hjorth CK [4]
  • Hornet V [4]
  • Lobel L [4]
  • Lutwama JJ [4]
  • Maurer DP [4]
  • Middlecamp M [4]
  • Mishra AK [4]
  • Pauli NT [4]
  • Rao G [4]
  • Shin OS [4]
  • Stuart L [4]
  • Walker LM [4]
  • Zeitlin L [4]
  • Deng F [3]
  • Hu Z [3]
  • Li L [3]
  • Liu J [3]
  • Liu Y [3]
  • Peng L [3]
  • Shen J [3]
  • Shu Y [3]
  • Wang M [3]
  • Xiao Q [3]
  • Yan B [3]
  • Liu B [2]
  • Wang D [2]
  • Yang G [2]
  • Batchelor TG [1]
  • Li N [1]
  • Li Z [1]
  • Mcfadden E [1]
  • Ramamohan AR [1]
  • Tian K [1]
  • Tse AL [1]
  • Yin J [1]

Author by ORCID

  • Wang A [5]
  • Mclellan JS [5]
  • Cao S [4]
  • Hornet V [4]
  • Wang M [3]
  • Liu B [2]
  • Wang D [2]

Journal

  • TO BE PUBLISHED [7]
  • CELL REP [4]
  • PLOS PATHOG [3]
  • NAT MICROBIOL [2]
  • ACTA CRYSTALLOGR D STRUCT BIOL [1]
  • BIORXIV [1]
  • CELL [1]
  • VIROL SIN [1]

Software

  • CRYOSPARC [13]

Microscope

  • TFS KRIOS [9]
  • FEI TITAN KRIOS [5]
  • JEOL CRYO ARM 300 [4]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • GATAN K3 6K X 4K [9]
  • TFS FALCON 4I 4K X 4K [7]
  • GATAN K3 BIOCONTINUUM 6K X 4K [2]

External links

  • AlphaFold DB [18]
  • PDB [18]
  • PDBe-Kb [18]
  • UniProt [18]
  • Pfam [15]
  • ChEBI [10]
  • ChEMBL [10]
  • DrugBank [9]
  • InterPro [6]
  • Complex Portal [4]
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Showing 1 - 10 of 18. Page 1 of 2
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EMD-66754
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Crimean-Congo hemorrhagic fever virus RNA polymerase
CryoEM
Release date: May 6, 2026
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 9xd4
Q-score: 0.443

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66755
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with the 5 vRNA
CryoEM
Release date: May 6, 2026
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 9xd5
Q-score: 0.474

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66756
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase in complex with the 3 vRNA
CryoEM
Release date: May 6, 2026
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 9xd6
Q-score: 0.513

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66783
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated 2FC
CryoEM
Release date: May 6, 2026
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 9xe6
Q-score: 0.4

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66784
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated cytidine
CryoEM
Release date: May 6, 2026
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 9xe7
Q-score: 0.408

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66785
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 15-bp RNA product
CryoEM
Release date: May 6, 2026
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 9xe9
Q-score: 0.441

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-66787
Download Map
3D View
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 9-bp RNA product
CryoEM
Release date: May 6, 2026
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 9xec
Q-score: 0.361

Xue L, Gui J, Pan H, Chang T, Xiong X

To Be Published

EMD-72752
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2.62A cryo-EM structure of RNA-directed RNA polymerase L of Crimean-Congo hemorrhagic fever virus Apo state
CryoEM
Release date: March 4, 2026
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 9ybm
Q-score: 0.537

Wang D, Yang G, Liu B

Nat Microbiol (2026) [ Pubmed: 41991608 DOI: doi:10.1038/s41564-026-02319-1 ]

EMD-72753
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2.53A cryo-EM structure of RNA-directed RNA polymerase L of Crimean-Congo hemorrhagic fever virus RNA bound
CryoEM
Release date: March 4, 2026
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 9ybn
Q-score: 0.561

Wang D, Yang G, Liu B

Nat Microbiol (2026) [ Pubmed: 41991608 DOI: doi:10.1038/s41564-026-02319-1 ]

EMD-44347
Download Map
3D View
GP38-GnH-DS-Gc in the pre-fusion conformation
CryoEM
Release date: Dec. 11, 2024
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 9b8j
Q-score: 0.474

McFadden E, Monticelli SR, Wang A, Ramamohan AR, Batchelor TG, Kuehne AI, Bakken RR, Tse AL, Chandran K, Herbert AS, McLellan JS

Cell (2025) 188 pp. 303-315.e13 [ Pubmed: 39701101 DOI: doi:10.1016/j.cell.2024.11.008 ]

Sort by: Download
Showing 1 - 10 of 18. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [10]
  • RNA [7]

Organism

  • Crimean-congo hemorrhagic fever orthonairovirus [18]
  • Homo sapiens [5]
  • Mus musculus [2]
  • Orthonairovirus haemorrhagiae [2]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [9]
  • ≥ 3Å and < 4Å [6]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [2]

Model molecular weight

  • 50-100 kDa [2]
  • 100-250 kDa [3]
  • 250-500 kDa [10]

Release Date

  • 2026 [9]
  • 2024 [8]
  • 2022 [1]

Author by name

  • Chang T [7]
  • Gui J [7]
  • Li J [7]
  • Pan H [7]
  • Xiong X [7]
  • Xue L [7]
  • Bakken RR [5]
  • Chandran K [5]
  • Herbert AS [5]
  • Kuehne AI [5]
  • Mclellan JS [5]
  • Monticelli SR [5]
  • Wang A [5]
  • Abelson D [4]
  • Balinandi S [4]
  • Barajas J [4]
  • Berrigan J [4]
  • Cao S [4]
  • Champney E [4]
  • Chong T [4]
  • Doyle M [4]
  • Dye JM [4]
  • Fu Y [4]
  • Hjorth CK [4]
  • Hornet V [4]
  • Lobel L [4]
  • Lutwama JJ [4]
  • Maurer DP [4]
  • Middlecamp M [4]
  • Mishra AK [4]
  • Pauli NT [4]
  • Rao G [4]
  • Shin OS [4]
  • Stuart L [4]
  • Walker LM [4]
  • Zeitlin L [4]
  • Deng F [3]
  • Hu Z [3]
  • Li L [3]
  • Liu J [3]
  • Liu Y [3]
  • Peng L [3]
  • Shen J [3]
  • Shu Y [3]
  • Wang M [3]
  • Xiao Q [3]
  • Yan B [3]
  • Liu B [2]
  • Wang D [2]
  • Yang G [2]
  • Batchelor TG [1]
  • Li N [1]
  • Li Z [1]
  • Mcfadden E [1]
  • Ramamohan AR [1]
  • Tian K [1]
  • Tse AL [1]
  • Yin J [1]

Author by ORCID

  • Wang A [5]
  • Mclellan JS [5]
  • Cao S [4]
  • Hornet V [4]
  • Wang M [3]
  • Liu B [2]
  • Wang D [2]

Journal

  • TO BE PUBLISHED [7]
  • CELL REP [4]
  • PLOS PATHOG [3]
  • NAT MICROBIOL [2]
  • ACTA CRYSTALLOGR D STRUCT BIOL [1]
  • BIORXIV [1]
  • CELL [1]
  • VIROL SIN [1]

Software

  • CRYOSPARC [13]

Microscope

  • TFS KRIOS [9]
  • FEI TITAN KRIOS [5]
  • JEOL CRYO ARM 300 [4]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • GATAN K3 6K X 4K [9]
  • TFS FALCON 4I 4K X 4K [7]
  • GATAN K3 BIOCONTINUUM 6K X 4K [2]

External links

  • AlphaFold DB [18]
  • PDB [18]
  • PDBe-Kb [18]
  • UniProt [18]
  • Pfam [15]
  • ChEBI [10]
  • ChEMBL [10]
  • DrugBank [9]
  • InterPro [6]
  • Complex Portal [4]